Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines.
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Mutations in the SBDS gene in acquired aplastic anemiaDisruptive chemicals, senescence and immortalityPlasmodium falciparum telomerase: de novo telomere addition to telomeric and nontelomeric sequences and role in chromosome healingTelomerase as a Cancer Target. Development of New MoleculesImmortality of cell lines: challenges and advantages of establishmentTelomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent mechanismsIn vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIsMyc activates telomeraseA highly selective telomerase inhibitor limiting human cancer cell proliferationIdentification of a quinoxaline derivative that is a potent telomerase inhibitor leading to cellular senescence of human cancer cells.Natural and pharmacological regulation of telomeraseTargeting human telomerase for cancer therapeutics.Role of telomerase in cellular proliferation and cancer.Telomerase. A target for anticancer therapy.Telomerase: therapeutic potential in cancer.Attachment of HeT-A sequences to chromosomal termini in Drosophila melanogaster may occur by different mechanisms.Aging and HIV/AIDS: pathogenetic role of therapeutic side effectsRAD50 function is essential for telomere maintenance in Arabidopsis.Alternative lengthening of telomeres in mammalian cells.HIV infection, inflammation, immunosenescence, and aging.Conversion of normal to malignant phenotype: telomere shortening, telomerase activation, and genomic instability during immortalization of human oral keratinocytes.Telomere maintenance mechanisms as a target for drug development.Leukocyte telomere length in HIV-infected and HIV-exposed uninfected children: shorter telomeres with uncontrolled HIV viremia.A small molecule inhibitor of Pot1 binding to telomeric DNA.Telomerase as a therapeutic target for malignant gliomas.Chromosome break-induced DNA replication leads to nonreciprocal translocations and telomere capture.Dynamics of telomeric DNA turnover in yeast.Tiptoeing to chromosome tips: facts, promises and perils of today's human telomere biology.Telomerase as a diagnostic and therapeutic target for cancer.Pharmacodynamics of telomerase inhibition and telomere shortening by noncytotoxic suramin.Phenyl 1,2,3-triazole-thymidine ligands stabilize G-quadruplex DNA, inhibit DNA synthesis and potentially reduce tumor cell proliferation over 3'-azido deoxythymidine.Molecular interactions of 'high risk' human papillomaviruses E6 and E7 oncoproteins: implications for tumour progression.Toward the design of a catalytic metallodrug: selective cleavage of G-quadruplex telomeric DNA by an anticancer copper-acridine-ATCUN complexTelomerase as a novel and potentially selective target for cancer chemotherapy.Telomere maintenance in childhood primitive neuroectodermal brain tumors.Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence.HIV Infection Is Associated with Shortened Telomere Length in Ugandans with Suspected TuberculosisTelomerase and its potential for therapeutic intervention.AZT as a telomerase inhibitor.3'-Azido-2',3'-dideoxynucleoside 5'-triphosphates inhibit telomerase activity in vitro, and the corresponding nucleosides cause telomere shortening in human HL60 cells.
P2860
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P2860
Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Effects of reverse transcripta ...... immortalized human cell lines.
@ast
Effects of reverse transcripta ...... immortalized human cell lines.
@en
type
label
Effects of reverse transcripta ...... immortalized human cell lines.
@ast
Effects of reverse transcripta ...... immortalized human cell lines.
@en
prefLabel
Effects of reverse transcripta ...... immortalized human cell lines.
@ast
Effects of reverse transcripta ...... immortalized human cell lines.
@en
P2860
P356
P1476
Effects of reverse transcripta ...... immortalized human cell lines.
@en
P2093
P2860
P356
10.1128/MCB.16.1.53
P407
P577
1996-01-01T00:00:00Z