DNA immunization circumvents deficient induction of T helper type 1 and cytotoxic T lymphocyte responses in neonates and during early life
about
CpG DNA can induce strong Th1 humoral and cell-mediated immune responses against hepatitis B surface antigen in young miceRSV fusion (F) protein DNA vaccine provides partial protection against viral infectionProtective T-cell-based immunity induced in neonatal mice by a single replicative cycle of herpes simplex virusDevelopment of neonatal Th1/Th2 function.Cellular immune responses in neonates.Vaccination in the neonatal period and early infancy.DNA vaccination and the immune responsiveness of neonates.Neonatal immunity and somatic mutation.Characterization of immune responses induced by intramuscular vaccination with DNA vaccines encoding measles virus hemagglutinin and/or fusion proteins.Extending the CD4(+) T-cell epitope specificity of the Th1 immune response to an antigen using a Salmonella enterica serovar typhimurium delivery vehicle.Yersinia enterocolitica promotes robust mucosal inflammatory T-cell immunity in murine neonatesUnbalanced Neonatal CD4(+) T-Cell ImmunityDevelopment of interleukin-12-producing capacity throughout childhoodDendritic cell immaturity during infancy restricts the capacity to express vaccine-specific T-cell memory.Neonates mount robust and protective adult-like CD8(+)-T-cell responses to DNA vaccines.Maternal vaccination: moving the science forward.Attenuated Salmonella enterica serovar Typhi and Shigella flexneri 2a strains mucosally deliver DNA vaccines encoding measles virus hemagglutinin, inducing specific immune responses and protection in cotton rats.CD4+ T lymphocytes are critical mediators of tumor immunity to simian virus 40 large tumor antigen induced by vaccination with plasmid DNA.Sublingual immunization of trivalent human papillomavirus DNA vaccine in baculovirus nanovector for protection against vaginal challenge.Low maternal viral loads and reduced granulocyte-macrophage colony-stimulating factor levels characterize exposed, uninfected infants who develop protective human immunodeficiency virus type 1-specific responses.Coxsackievirus B3 and the neonatal CNS: the roles of stem cells, developing neurons, and apoptosis in infection, viral dissemination, and disease.Protracted course of lymphocytic choriomeningitis virus WE infection in early life: induction but limited expansion of CD8+ effector T cells and absence of memory CD8+ T cells.Immunization of pregnant women: Future of early infant protection.Mucosally delivered Salmonella live vector vaccines elicit potent immune responses against a foreign antigen in neonatal mice born to naive and immune mothers.Rapid Evolution of the CD8+ TCR Repertoire in Neonatal MiceMurine neonates develop vigorous in vivo cytotoxic and Th1/Th2 responses upon exposure to low doses of NIMA-like alloantigens.Murine neonatal recent thymic emigrants are phenotypically and functionally distinct from adult recent thymic emigrants.Immune adjuvants in early life: targeting the innate immune system to overcome impaired adaptive response.Progress in the development of DNA vaccines against foot-and-mouth disease.Gene-based neonatal immune priming potentiates a mucosal adenoviral vaccine encoding mycobacterial Ag85B.Immune responses following neonatal DNA vaccination are long-lived, abundant, and qualitatively similar to those induced by conventional immunization.Intranasal immunization with pneumococcal conjugate vaccines with LT-K63, a nontoxic mutant of heat-Labile enterotoxin, as adjuvant rapidly induces protective immunity against lethal pneumococcal infections in neonatal mice.Pulmonary Dendritic Cell Subsets Shape the Respiratory Syncytial Virus-Specific CD8+ T Cell Immunodominance Hierarchy in Neonates.The key regulators of adult T helper cell responses, STAT6 and T-bet, are established in early life in miceExperimental infection of neonatal foals with Rhodococcus equi triggers adult-like gamma interferon induction.Cellular immune response of fetuses to cytomegalovirus.Infection of mice with respiratory syncytial virus during neonatal life primes for enhanced antibody and T cell responses on secondary challenge.Development of mixed Th1/Th2 type immune response and protection against Mycobacterium tuberculosis after rectal or subcutaneous immunization of newborn and adult mice with Mycobacterium bovis BCG.Combining DNA and protein vaccines for early life immunization against respiratory syncytial virus in mice.Safety and Immunogenicity of Malaria Vectored Vaccines Given with Routine Expanded Program on Immunization Vaccines in Gambian Infants and Neonates: A Randomized Controlled Trial.
P2860
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P2860
DNA immunization circumvents deficient induction of T helper type 1 and cytotoxic T lymphocyte responses in neonates and during early life
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
DNA immunization circumvents d ...... neonates and during early life
@ast
DNA immunization circumvents d ...... neonates and during early life
@en
type
label
DNA immunization circumvents d ...... neonates and during early life
@ast
DNA immunization circumvents d ...... neonates and during early life
@en
prefLabel
DNA immunization circumvents d ...... neonates and during early life
@ast
DNA immunization circumvents d ...... neonates and during early life
@en
P2093
P2860
P356
P1476
DNA immunization circumvents d ...... neonates and during early life
@en
P2093
Lambert PH
Martinez X
Saddallah F
Siegrist CA
P2860
P304
P356
10.1073/PNAS.94.16.8726
P407
P577
1997-08-01T00:00:00Z