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Related Mechanisms of Antibody Somatic Hypermutation and Class Switch RecombinationIgH chain class switch recombination: mechanism and regulationActivation-induced deoxycytidine deaminase (AID) co-transcriptional scanning at single-molecule resolution.Emerging concepts of epigenetic dysregulation in hematological malignanciesRNA Exosome Regulates AID DNA Mutator Activity in the B Cell GenomeAn Epigenetics-Inspired DNA-Based Data Storage SystemNew paradigms for functional HIV-specific nonneutralizing antibodiesProgression from IgD+ IgM+ to isotype-switched B cells is site specific during coronavirus-induced encephalomyelitis.DNA repair mechanisms and their biological roles in the malaria parasite Plasmodium falciparum.Receptor revision in CD4 T cells is influenced by follicular helper T cell formation and germinal-center interactions.Overlapping hotspots in CDRs are critical sites for V region diversificationTargeting of somatic hypermutation by immunoglobulin enhancer and enhancer-like sequences.miR-182 is largely dispensable for adaptive immunity: lack of correlation between expression and function.Noncoding RNA transcription targets AID to divergently transcribed loci in B cells.MicroRNA 155 control of p53 activity is context dependent and mediated by Aicda and Socs1.Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm.Local DNA dynamics shape mutational patterns of mononucleotide repeats in human genomesActivation-induced cytidine deaminase in B cells of hepatits C virus-related cryoglobulinaemic vasculitis.Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolutionCXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis.A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch RecombinationE3-ubiquitin ligase Nedd4 determines the fate of AID-associated RNA polymerase II in B cells.Theory and strategy for Pneumococcal vaccines in the elderly.Somatic inactivation of Tp53 in hematopoietic stem cells or thymocytes predisposes mice to thymic lymphomas with clonal translocations.Transgenic mouse model of IgM+ lymphoproliferative disease mimicking Waldenström macroglobulinemia.Human apurinic/apyrimidinic endonuclease 1.Waldenström macroglobulinemia: clinical and immunological aspects, natural history, cell of origin, and emerging mouse modelsUbiquitination events that regulate recombination of immunoglobulin Loci gene segments.Control of Transposon-Mediated Directed Mutation by the Escherichia coli Phosphoenolpyruvate:Sugar Phosphotransferase System.Programmed DNA breaks in lymphoid cells: repair mechanisms and consequences in human diseaseHistone H3.3 promotes IgV gene diversification by enhancing formation of AID-accessible single-stranded DNA.RNA Exosome and Non-coding RNA-Coupled Mechanisms in AID-Mediated Genomic Alterations.Recent advances in the study of immunodeficiency and DNA damage response.DNA repair and systemic lupus erythematosus.miRNAs in B Cell Development and Lymphomagenesis.Blimp-1-dependent and -independent natural antibody production by B-1 and B-1-derived plasma cells.Binding of estrogen receptors to switch sites and regulatory elements in the immunoglobulin heavy chain locus of activated B cells suggests a direct influence of estrogen on antibody expression.Hodgkin Lymphoma Cells Have a Specific Long Noncoding RNA Expression Pattern.Understanding the multiple biological aspects leading to myelomaT Follicular Helper Cells and B Cell Dysfunction in Aging and HIV-1 Infection.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Regulation of AID, the B-cell genome mutator.
@ast
Regulation of AID, the B-cell genome mutator.
@en
type
label
Regulation of AID, the B-cell genome mutator.
@ast
Regulation of AID, the B-cell genome mutator.
@en
prefLabel
Regulation of AID, the B-cell genome mutator.
@ast
Regulation of AID, the B-cell genome mutator.
@en
P2093
P2860
P356
P1433
P1476
Regulation of AID, the B-cell genome mutator.
@en
P2093
Celia Keim
David Kazadi
Gerson Rothschild
Uttiya Basu
P2860
P356
10.1101/GAD.200014.112
P577
2013-01-01T00:00:00Z