Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells - Wikidata - awgldk - TriplyDB

Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells

Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells

http://www.wikidata.org/entity/Q36558691

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Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases Vascular Remodelling and Mesenchymal Transition in Systemic Sclerosis Emerging Role and Therapeutic Implication of Wnt Signaling Pathways in Autoimmune Diseases MicroRNAs Regulating Signaling Pathways: Potential Biomarkers in Systemic Sclerosis Signaling in Fibrosis: TGF-β, WNT, and YAP/TAZ Converge Scleroderma pathogenesis: a pivotal role for fibroblasts as effector cells Dissecting the heterogeneity of skin gene expression patterns in systemic sclerosis Identification of cadherin 11 as a mediator of dermal fibrosis and possible role in systemic sclerosis.Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies.Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis.A Wnt-TGFβ2 axis induces a fibrogenic program in muscle stem cells from dystrophic mice.Sustained β-catenin activity in dermal fibroblasts promotes fibrosis by up-regulating expression of extracellular matrix protein-coding genes.Fibrosis in systemic sclerosis: common and unique pathobiology.Regulation of Matrix Remodeling by Peroxisome Proliferator-Activated Receptor-γ: A Novel Link Between Metabolism and Fibrogenesis.Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis.2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine is an anti-inflammatory TLR-2, -4 and -5 response mediator in human monocytes.Targeting miR-155 to Treat Experimental Scleroderma Adiponectin inhibits Wnt co-receptor, Lrp6, phosphorylation and β-catenin signaling.Role of endothelial to mesenchymal transition in the pathogenesis of the vascular alterations in systemic sclerosis.Morphogen pathways in systemic sclerosis.Molecular basis of organ fibrosis: potential therapeutic approaches.What does global gene expression profiling tell us about the pathogenesis of systemic sclerosis?Canonical Wnt signalling as a key regulator of fibrogenesis - implications for targeted therapies?Novel investigational agents for the treatment of scleroderma.Integrins and cadherins as therapeutic targets in fibrosis.Molecular and cellular basis of scleroderma.Stroma as an Active Player in the Development of the Tumor Microenvironment.Current frontiers in systemic sclerosis pathogenesis.Unfolding the pathogenesis of scleroderma through genomics and epigenomics.Critical Appraisal of the Utility and Limitations of Animal Models of Scleroderma.Canonical Wnt signaling in systemic sclerosis.Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of Systemic Sclerosis-associated pulmonary fibrosis and pulmonary arterial hypertension. Myth or reality?Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis.Hepatocellular Carcinoma-propagating Cells are Detectable by Side Population Analysis and Possess an Expression Profile Reflective of a Primitive Origin Activation of Wnt/β-catenin signalling is required for TGF-β/Smad2/3 signalling during myofibroblast proliferation.Cytoskeleton and nuclear lamina affection in recessive osteogenesis imperfecta: A functional proteomics perspective.Connective tissue disease: SSc-fibrosis takes flight with Wingless inhibition.Sustained β-catenin activity in dermal fibroblasts is sufficient for skin fibrosis.WNT/β-catenin signaling induces IL-1β expression by alveolar epithelial cells in pulmonary fibrosis.TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases.

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P2860

Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells

http://www.wikidata.org/entity/Q36558691

description

2012 nî lūn-bûn

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

Wnt/β-catenin signaling is hyp ...... responses in mesenchymal cells

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Wnt/β-catenin signaling is hyp ...... responses in mesenchymal cells

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type

label

Wnt/β-catenin signaling is hyp ...... responses in mesenchymal cells

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Wnt/β-catenin signaling is hyp ...... responses in mesenchymal cells

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prefLabel

Wnt/β-catenin signaling is hyp ...... responses in mesenchymal cells

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Wnt/β-catenin signaling is hyp ...... responses in mesenchymal cells

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Arthritis and Rheumatism

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Wnt/β-catenin signaling is hyp ...... responses in mesenchymal cells

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Anna P Lam

http://www.w3.org/2001/XMLSchema#string

Emily Hamburg

http://www.w3.org/2001/XMLSchema#string

Feng Fang

http://www.w3.org/2001/XMLSchema#string

Jennifer L Sargent

http://www.w3.org/2001/XMLSchema#string

John Varga

http://www.w3.org/2001/XMLSchema#string

Jun Wei

http://www.w3.org/2001/XMLSchema#string

Michael L Whitfield

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Monique E Hinchcliff

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Radhika Atit

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P2860

A deep investigation into the adipogenesis mechanism: profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/beta-catenin signaling pathway

WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis

Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice

Secreted antagonists of the Wnt signalling pathway

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

Role for ICAT in beta-catenin-dependent nuclear signaling and cadherin functions.

Idiopathic pulmonary fibrosis: aberrant recapitulation of developmental programs?

Transcriptional program induced by Wnt protein in human fibroblasts suggests mechanisms for cell cooperativity in defining tissue microenvironments.

Functional Wnt signaling is increased in idiopathic pulmonary fibrosis

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2734-2745

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10.1002/ART.34424

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8

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64

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Cara J Gottardi

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2012-08-01T00:00:00Z

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221826456

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22328118

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3553791

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