about
Alzheimer's disease as homeostatic responses to age-related myelin breakdownLRRK2 kinase regulates synaptic morphology through distinct substrates at the presynaptic and postsynaptic compartments of the Drosophila neuromuscular junctionPotential therapeutic interest of adenosine A2A receptors in psychiatric disorders.CSPĪ± knockout causes neurodegeneration by impairing SNAP-25 functionSynaptic defects in the spinal and neuromuscular circuitry in a mouse model of spinal muscular atrophyThe Spontaneous Ataxic Mouse Mutant Tippy is Characterized by a Novel Purkinje Cell Morphogenesis and Degeneration Phenotype.Axonal degeneration as a self-destructive defense mechanism against neurotropic virus infectionDisruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid betaMorphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathwayInhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinaseA central role for calcineurin in protein misfolding neurodegenerative diseases.Synaptic mutant huntingtin inhibits synapsin-1 phosphorylation and causes neurological symptoms.Local caspase activation interacts with Slit-Robo signaling to restrict axonal arborization.Sphingosine 1-phosphate lyase ablation disrupts presynaptic architecture and function via an ubiquitin- proteasome mediated mechanism.Expression of the neuroprotective slow Wallerian degeneration (WldS) gene in non-neuronal tissues.Dynamic remodelling of synapses can occur in the absence of the parent cell bodyApolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's diseaseA neurotoxic phosphoform of Elk-1 associates with inclusions from multiple neurodegenerative diseases.Caffeine consumption prevents diabetes-induced memory impairment and synaptotoxicity in the hippocampus of NONcZNO10/LTJ mice.Functional neuromuscular junctions formed by embryonic stem cell-derived motor neurons.Synaptic protection in the brain of WldS mice occurs independently of age but is sensitive to gene-dose.Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivoCHMP2B mutants linked to frontotemporal dementia impair maturation of dendritic spines.The intricate mechanisms of neurodegeneration in prion diseases.1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase CNMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.Molecular neuropathology of the synapse in sheep with CLN5 Batten diseaseDifferential proteomics analysis of synaptic proteins identifies potential cellular targets and protein mediators of synaptic neuroprotection conferred by the slow Wallerian degeneration (Wlds) gene.Modified cell cycle status in a mouse model of altered neuronal vulnerability (slow Wallerian degeneration; Wlds).Distinct regulation of cell cycle and survival in lymphocytes from patients with Alzheimer's disease and amyotrophic lateral sclerosisSpatiotemporal localization of injury potentials in DRG neurons during vincristine-induced axonal degeneration.Autophagy in neurite injury and neurodegeneration: in vitro and in vivo models.GDNF control of the glutamatergic cortico-striatal pathway requires tonic activation of adenosine A receptors.Bcl-x L increases mitochondrial fission, fusion, and biomass in neurons.Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease.NMNATs, evolutionarily conserved neuronal maintenance factors.Characterization of early pathogenesis in the SOD1(G93A) mouse model of ALS: part II, results and discussionNMJ-morph reveals principal components of synaptic morphology influencing structure-function relationships at the neuromuscular junction.Axonal transport defects in neurodegenerative diseases.Role of calcineurin in neurodegeneration produced by misfolded proteins and endoplasmic reticulum stress.
P2860
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P2860
description
2006 nĆ® lÅ«n-bĆ»n
@nan
2006幓ć®č«ę
@ja
2006幓č«ę
@yue
2006幓č«ę
@zh-hant
2006幓č«ę
@zh-hk
2006幓č«ę
@zh-mo
2006幓č«ę
@zh-tw
2006幓č®ŗę
@wuu
2006幓č®ŗę
@zh
2006幓č®ŗę
@zh-cn
name
Synaptic vulnerability in neurodegenerative disease.
@ast
Synaptic vulnerability in neurodegenerative disease.
@en
type
label
Synaptic vulnerability in neurodegenerative disease.
@ast
Synaptic vulnerability in neurodegenerative disease.
@en
prefLabel
Synaptic vulnerability in neurodegenerative disease.
@ast
Synaptic vulnerability in neurodegenerative disease.
@en
P1476
Synaptic vulnerability in neurodegenerative disease.
@en
P2093
Simon H Parson
P304
P356
10.1097/01.JNEN.0000228202.35163.C4
P577
2006-08-01T00:00:00Z