Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events.
about
CDO: an oncogene-, serum-, and anchorage-regulated member of the Ig/fibronectin type III repeat familyRole of the F-box protein Skp2 in adhesion-dependent cell cycle progressionCyclin A is a c-Jun target gene and is necessary for c-Jun-induced anchorage-independent growth in RAT1a cellsFra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcriptionCDO, a robo-related cell surface protein that mediates myogenic differentiationEpidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells.Oncogenic H-Ras V12 promotes anchorage-independent cytokinesis in human fibroblastsAccumulation of neoplastic traits prior to spontaneous in vitro transformation of rat cholangiocytes determines susceptibility to activated ErbB-2/Neu.The structural and mechanical complexity of cell-growth control.Ras-induced colony formation and anchorage-independent growth inhibited by elevated expression of Puralpha in NIH3T3 cells.A functional single nucleotide polymorphism at the promoter region of cyclin A2 is associated with increased risk of colon, liver, and lung cancers.Kras activation in p53-deficient myoblasts results in high-grade sarcoma formation with impaired myogenic differentiationAnchorage-dependent cell cycle progression.Dual stimulation of Ras/mitogen-activated protein kinase and RhoA by cell adhesion to fibronectin supports growth factor-stimulated cell cycle progression.PKCiota promotes ovarian tumor progression through deregulation of cyclin E.Control of cyclin D1, p27(Kip1), and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tensionModulation of the BRCA1 Protein and Induction of Apoptosis in Triple Negative Breast Cancer Cell Lines by the Polyphenolic Compound Curcumin.TALEN mediated targeted editing of GM2/GD2-synthase gene modulates anchorage independent growth by reducing anoikis resistance in mouse tumor cells.Silencing the mannose 6-phosphate/IGF-II receptor differentially affects tumorigenic properties of normal breast epithelial cells.Ras signals to the cell cycle machinery via multiple pathways to induce anchorage-independent growth.PI3K Acts in synergy with loss of PKC to elicit apoptosis via the UPR.The MCT-1 oncogene product impairs cell cycle checkpoint control and transforms human mammary epithelial cells.Long-term exposure to nicotine, via ras pathway, induces cyclin D1 to stimulate G1 cell cycle transition.Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3beta (GSK-3beta) in vitro.Matrix-independent activation of phosphatidylinositol 3-kinase, Stat3, and cyclin A-associated Cdk2 Is essential for anchorage-independent growth of v-Ros-transformed chicken embryo fibroblasts.Cyclin D1 overexpression in a model of human breast premalignancy: preferential stimulation of anchorage-independent but not anchorage-dependent growth is associated with increased cdk2 activity.Multiple stages and genetic alterations in immortalization, malignant transformation, and tumor progression of human skin keratinocytes.Extracellular ATP induces anchorage-independent expression of cyclin A and rescues the transformed phenotype of a ras-resistant mutant cell line.Geminin functions downstream of p53 in K-ras-induced gene amplification of dihydrofolate reductase.Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton.Establishment and characterization of cetuximab resistant head and neck squamous cell carcinoma cell lines: focus on the contribution of the AP-1 transcription factor.The effects of cell adhesion on the growth and protein productivity of animal cells.Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells.Changes in cell shape and anchorage in relation to the restriction point.Stat3 plays an important role in oncogenic Ros- and insulin-like growth factor I receptor-induced anchorage-independent growth.Retinoblastoma susceptibility gene product (pRb) and p107 functionally separate the requirements for serum and anchorage in the cell cycle G1-phase.Kinesin family member 14: an independent prognostic marker and potential therapeutic target for ovarian cancer.Chromium IV exposure, via Src/Ras signaling, promotes cell transformation.The Yeast Saccharomyces cerevisiae as a Model for Understanding RAS Proteins and their Role in Human Tumorigenesis.
P2860
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P2860
Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Ras induces anchorage-independ ...... n-regulated cell cycle events.
@ast
Ras induces anchorage-independ ...... n-regulated cell cycle events.
@en
type
label
Ras induces anchorage-independ ...... n-regulated cell cycle events.
@ast
Ras induces anchorage-independ ...... n-regulated cell cycle events.
@en
prefLabel
Ras induces anchorage-independ ...... n-regulated cell cycle events.
@ast
Ras induces anchorage-independ ...... n-regulated cell cycle events.
@en
P2860
P356
P1476
Ras induces anchorage-independ ...... n-regulated cell cycle events.
@en
P2093
P2860
P304
P356
10.1128/MCB.16.7.3370
P407
P577
1996-07-01T00:00:00Z