Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism.
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TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblastsThe application of the comet assay to assess the genotoxicity of environmental pollutants in the nematode Caenorhabditis elegansInflammation-associated extracellular β-glucuronidase alters cellular responses to the chemical carcinogen benzo[a]pyrenePolycyclic aromatic hydrocarbons and cytochrome P450 in HIV pathogenesis.Effect of Polyaryl Hydrocarbons on Cytotoxicity in Monocytic Cells: Potential Role of Cytochromes P450 and Oxidative Stress Pathways.The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) miceMetabolic activation of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine and DNA adduct formation depends on p53: Studies in Trp53(+/+),Trp53(+/-) and Trp53(-/-) miceOral exposure to commercially available coal tar-based pavement sealcoat induces murine genetic damage and mutations.NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene.Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a]pyrene via its histone deacetylase activity in colon epithelial cell models.Development of In Silico Protocols to Predict Structural Insights into the Metabolic Activation Pathways of Xenobiotics.NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1.Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine.Transcriptional Profiling of Dibenzo[def,p]chrysene-induced Spleen Atrophy Provides Mechanistic Insights into its Immunotoxicity in MutaMouse.Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone.Benchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene.Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems.Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice.Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of "luminal" muscle-invasive bladder cancers.Carcinogens and DNA damage
P2860
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P2860
Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism.
description
2014 nî lūn-bûn
@nan
2014年の論文
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2014年論文
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2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
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2014年论文
@zh-cn
name
Carcinogenic polycyclic aromat ...... via a p53-dependent mechanism.
@ast
Carcinogenic polycyclic aromat ...... via a p53-dependent mechanism.
@en
type
label
Carcinogenic polycyclic aromat ...... via a p53-dependent mechanism.
@ast
Carcinogenic polycyclic aromat ...... via a p53-dependent mechanism.
@en
prefLabel
Carcinogenic polycyclic aromat ...... via a p53-dependent mechanism.
@ast
Carcinogenic polycyclic aromat ...... via a p53-dependent mechanism.
@en
P2093
P2860
P1476
Carcinogenic polycyclic aromat ...... via a p53-dependent mechanism
@en
P2093
Albrecht Seidel
Annette M Krais
Jill E Kucab
Julia Stertmann
Laura E Wohak
Steinar Øvrebø
P2860
P2888
P304
P356
10.1007/S00204-014-1409-1
P577
2014-11-15T00:00:00Z