A 5' differentially methylated sequence and the 3'-flanking region are necessary for H19 transgene imprinting
about
CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locusThe many roles of the transcriptional regulator CTCFLoss of the maternal H19 gene induces changes in Igf2 methylation in both cis and transA silencer element identified in Drosophila is required for imprinting of H19 reporter transgenes in mice.Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2-H19 domain.Maintenance of paternal methylation and repression of the imprinted H19 gene requires MBD3Postnatal survival of mice with maternal duplication of distal chromosome 7 induced by a Igf2/H19 imprinting control region lacking insulator functionGenomic imprinting and chromatin insulation in Beckwith-Wiedemann syndrome.Characterization of novel parent-specific epigenetic modifications upstream of the imprinted mouse H19 gene.Competition--a common motif for the imprinting mechanism?Parental allele-specific chromatin configuration in a boundary-imprinting-control element upstream of the mouse H19 geneInvestigation of elements sufficient to imprint the mouse Air promoter.The absence of enhancer competition between Igf2 and H19 following transfer into differentiated cells.Analysis of sequence upstream of the endogenous H19 gene reveals elements both essential and dispensable for imprintingDNA methylation in genomic imprinting, development, and disease.Comparative genomic sequencing identifies novel tissue-specific enhancers and sequence elements for methylation-sensitive factors implicated in Igf2/H19 imprintingH19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19.A transcriptional insulator at the imprinted H19/Igf2 locus.Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2.Analysis of the H19ICR insulatorIdentification of a silencing element in the human 15q11-q13 imprinting center by using transgenic Drosophila.Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7.The role of DMDs in the maintenance of epigenetic states.A randomly integrated transgenic H19 imprinting control region acquires methylation imprinting independently of its establishment in germ cells.The H19 differentially methylated region marks the parental origin of a heterologous locus without gametic DNA methylation.Matrix-attachment regions in the mouse chromosome 7F imprinted domain.A 5' 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development.Genomic structure and parent-of-origin-specific methylation of Peg1.Tandem repeat hypothesis in imprinting: deletion of a conserved direct repeat element upstream of H19 has no effect on imprinting in the Igf2-H19 region.Chromatin conformation of the H19 epigenetic mark.The paternal methylation imprint of the mouse H19 locus is acquired in the gonocyte stage during foetal testis development.Establishment and maintenance of H19 imprinting in the germline and preimplantation embryo.Imprinted expression of the Igf2r gene depends on an intronic CpG island.An imprinting element from the mouse H19 locus functions as a silencer in Drosophila.The imprinting box of the mouse Igf2r gene
P2860
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P2860
A 5' differentially methylated sequence and the 3'-flanking region are necessary for H19 transgene imprinting
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
A 5' differentially methylated ...... y for H19 transgene imprinting
@ast
A 5' differentially methylated ...... y for H19 transgene imprinting
@en
type
label
A 5' differentially methylated ...... y for H19 transgene imprinting
@ast
A 5' differentially methylated ...... y for H19 transgene imprinting
@en
prefLabel
A 5' differentially methylated ...... y for H19 transgene imprinting
@ast
A 5' differentially methylated ...... y for H19 transgene imprinting
@en
P2860
P356
P1476
A 5' differentially methylated ...... y for H19 transgene imprinting
@en
P2093
M S Bartolomei
P2860
P304
P356
10.1128/MCB.17.1.309
P407
P577
1997-01-01T00:00:00Z