Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism.
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Regulation of stearoyl coenzyme A desaturase expression in human retinal pigment epithelial cells by retinoic acidMouse P450RAI (CYP26) expression and retinoic acid-inducible retinoic acid metabolism in F9 cells are regulated by retinoic acid receptor gamma and retinoid X receptor alphaThe transcriptional corepressor TPA-inducible sequence 7 regulates adult axon growth through cellular retinoic acid binding protein II expressionSignalling Through Retinoic Acid Receptors is Required for Reprogramming of Both Mouse Embryonic Fibroblast Cells and Epiblast Stem Cells to Induced Pluripotent Stem CellsRetinoic acid induces expression of the interleukin-1beta gene in cultured normal human mammary epithelial cells and in human breast carcinoma lines.Retinoic acids potentiate BMP9-induced osteogenic differentiation of mesenchymal progenitor cells.Coordinated gene expression during gilthead sea bream skeletogenesis and its disruption by nutritional hypervitaminosis APhosphorylation of activation functions AF-1 and AF-2 of RAR alpha and RAR gamma is indispensable for differentiation of F9 cells upon retinoic acid and cAMP treatment.All-trans retinoic acid directs urothelial specification of murine embryonic stem cells via GATA4/6 signaling mechanisms.Reexpression of retinoic acid receptor (RAR) gamma or overexpression of RAR alpha or RAR beta in RAR gamma-null F9 cells reveals a partial functional redundancy between the three RAR types.Transcriptional regulation of laminin gene expression.Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinaseRetinoid regulated association of transcriptional co-regulators and the polycomb group protein SUZ12 with the retinoic acid response elements of Hoxa1, RARbeta(2), and Cyp26A1 in F9 embryonal carcinoma cells.Gene expression profiling elucidates a specific role for RARgamma in the retinoic acid-induced differentiation of F9 teratocarcinoma stem cellsCommon themes in the pathogenesis of acute myeloid leukemia.Cyclin proteolysis as a retinoid cancer prevention mechanism.Identification of a novel non-retinoid pan inverse agonist of the retinoic acid receptorsEpigenetic regulation by RARα maintains ligand-independent transcriptional activity.RXRalpha-null F9 embryonal carcinoma cells are resistant to the differentiation, anti-proliferative and apoptotic effects of retinoids.Retinoic acid receptor alpha function in vertebrate limb skeletogenesis: a modulator of chondrogenesis.Specific and redundant functions of retinoid X Receptor/Retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells.The effect pathway of retinoic acid through regulation of retinoic acid receptor alpha in gastric cancer cells.Cancer stem cells and differentiation therapy.Retardation of skeletal development and cervical abnormalities in transgenic mice expressing a dominant-negative retinoic acid receptor in chondrogenic cells.Synergistic activation of retinoic acid (RA)-responsive genes and induction of embryonal carcinoma cell differentiation by an RA receptor alpha (RAR alpha)-, RAR beta-, or RAR gamma-selective ligand in combination with a retinoid X receptor-specificDistinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cells.SNF2beta-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells.RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cellsCDK1 interacts with RARγ and plays an important role in treatment response of acute myeloid leukemiaPolycomb recruitment attenuates retinoic acid-induced transcription of the bivalent NR2F1 gene.Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RAR beta 2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts.Retinoic acid receptor γ (Rarg) and nuclear receptor subfamily 5, group A, member 2 (Nr5a2) promote conversion of fibroblasts to functional neurons.Differences in gene expression between wild type and Hoxa1 knockout embryonic stem cells after retinoic acid treatment or leukemia inhibitory factor (LIF) removal.Murine laminin B1 gene regulation during the retinoic acid- and dibutyryl cyclic AMP-induced differentiation of embryonic F9 teratocarcinoma stem cells.Radiolabeling and initial biological evaluation of [18F]KBM-1 for imaging RAR-α receptors in neuroblastoma.Retinoic acid receptor gamma1 (RARgamma1) levels control RARbeta2 expression in SK-N-BE2(c) neuroblastoma cells and regulate a differentiation-apoptosis switch.Retinoic acid receptor isotype specificity in F9 teratocarcinoma stem cells results from the differential recruitment of coregulators to retinoic response elements.Conservation of Bmp2 post-transcriptional regulatory mechanisms.Alterations in cellular retinol metabolism contribute to differential retinoid responsiveness in normal human mammary epithelial cells versus breast cancer cells.4HPR triggers apoptosis but not differentiation in retinoid sensitive and resistant human embryonal carcinoma cells through an RARgamma independent pathway.
P2860
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P2860
Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Targeted disruption of retinoi ...... and retinoic acid metabolism.
@ast
Targeted disruption of retinoi ...... and retinoic acid metabolism.
@en
type
label
Targeted disruption of retinoi ...... and retinoic acid metabolism.
@ast
Targeted disruption of retinoi ...... and retinoic acid metabolism.
@en
prefLabel
Targeted disruption of retinoi ...... and retinoic acid metabolism.
@ast
Targeted disruption of retinoi ...... and retinoic acid metabolism.
@en
P2093
P2860
P356
P1476
Targeted disruption of retinoi ...... and retinoic acid metabolism.
@en
P2093
P2860
P304
P356
10.1128/MCB.15.2.843
P407
P577
1995-02-01T00:00:00Z