Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest
about
Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcriptionIdentification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phaseNPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcriptionExpression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entryThe cyclin E/Cdk2 substrate p220(NPAT) is required for S-phase entry, histone gene expression, and Cajal body maintenance in human somatic cellsNPAT expression is regulated by E2F and is essential for cell cycle progressionThe histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cyclesThe role of nuclear bodies in gene expression and disease.Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition.Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development.Coordinating cell cycle-regulated histone gene expression through assembly and function of the Histone Locus Body.Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos.
P2860
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P2860
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest
@ast
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest
@en
type
label
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest
@ast
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest
@en
prefLabel
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest
@ast
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest
@en
P2093
P2860
P1476
Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest
@en
P2093
B C Vanderhyden
M Di Fruscio
R Jaenisch
P2860
P304
P407
P577
1997-07-01T00:00:00Z