Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation
about
RINT-1, a novel Rad50-interacting protein, participates in radiation-induced G(2)/M checkpoint controlChk2 activation dependence on Nbs1 after DNA damageThe stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38gamma-independent pathwayBASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structuresStructure of a Second BRCT Domain Identified in the Nijmegen Breakage Syndrome Protein Nbs1 and its Function in an MDC1-Dependent Localization of Nbs1 to DNA Damage SitesRole of Nijmegen breakage syndrome protein in specific T-lymphocyte activation pathwaysThe MRE11-NBS1-RAD50 pathway is perturbed in SV40 large T antigen-immortalized AT-1, AT-2 and HL-1 cardiomyocytes.Enhanced CD95-mediated apoptosis contributes to radiation hypersensitivity of NBS lymphoblasts.The anti-proliferative effects of the CHFR depend on the forkhead associated domain, but not E3 ligase activity mediated by ring finger domain.The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response.Nijmegen breakage syndrome: consequences of defective DNA double strand break repair.Positional cloning and functional analysis of the gene responsible for Nijmegen breakage syndrome, NBS1.Requirement of ATM in phosphorylation of the human p53 protein at serine 15 following DNA double-strand breaks.Immunodeficiency associated with DNA repair defects.Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stressFine localization of the Nijmegen breakage syndrome gene to 8q21: evidence for a common founder haplotype.Genetic and epigenetic features in radiation sensitivity Part I: cell signalling in radiation response.Dual role of Nbs1 in the ataxia telangiectasia mutated-dependent DNA damage response.Cellular responses to ionising radiation of AT heterozygotes: differences between missense and truncating mutation carriers.Bcl-2 proteins in development, health, and disease of the hematopoietic system.The fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint.G2-phase radiation response in lymphoblastoid cell lines from Nijmegen breakage syndrome.ATM-dependent phosphorylation and accumulation of endogenous BLM protein in response to ionizing radiation.The p53 network.Positional cloning of the gene for Nijmegen breakage syndrome.AtATM is essential for meiosis and the somatic response to DNA damage in plants.Different roles of the Mre11 complex in the DNA damage response in Aspergillus nidulans.Meiotic localization of Mre11 and Rad50 in wild type, spo11-1, and MRN complex mutants of Coprinus cinereus.Mutant Nbs1 enhances cisplatin-induced DNA damage and cytotoxicity in head and neck cancer.
P2860
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P2860
Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Nijmegen breakage syndrome cel ...... exposure to ionizing radiation
@ast
Nijmegen breakage syndrome cel ...... exposure to ionizing radiation
@en
type
label
Nijmegen breakage syndrome cel ...... exposure to ionizing radiation
@ast
Nijmegen breakage syndrome cel ...... exposure to ionizing radiation
@en
prefLabel
Nijmegen breakage syndrome cel ...... exposure to ionizing radiation
@ast
Nijmegen breakage syndrome cel ...... exposure to ionizing radiation
@en
P2093
P2860
P356
P1476
Nijmegen breakage syndrome cel ...... exposure to ionizing radiation
@en
P2093
P2860
P304
P356
10.1128/MCB.17.9.5016
P407
P577
1997-09-01T00:00:00Z