Fluorescence-force spectroscopy maps two-dimensional reaction landscape of the holliday junction.
about
DNA replication at the single-molecule levelReal-time detection of cruciform extrusion by single-molecule DNA nanomanipulationSingle-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopyFrameshifting RNA pseudoknots: structure and mechanismClose encounters with DNAAllosteric ring assembly and chemo-mechanical melting by the interaction between 5'-phosphate and λ exonuclease.Structure of myosin filaments from relaxed Lethocerus flight muscle by cryo-EM at 6 Å resolution.Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics.Spider Silk Peptide Is a Compact, Linear Nanospring Ideal for Intracellular Tension Sensing.High-resolution optical tweezers for single-molecule manipulation.Single-molecule analysis reveals three phases of DNA degradation by an exonuclease.Mechanical unfolding of human telomere G-quadruplex DNA probed by integrated fluorescence and magnetic tweezers spectroscopy.Direct imaging of single UvrD helicase dynamics on long single-stranded DNAUltrahigh-resolution optical trap with single-fluorophore sensitivity.A practical guide to single-molecule FRETIn situ structure and dynamics of DNA origami determined through molecular dynamics simulations.DNA Y structure: a versatile, multidimensional single molecule assay.A programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI headsIOFF generally extends fluorophore longevity in the presence of an optical trap.Single-molecule three-color FRET with both negligible spectral overlap and long observation time.Minute negative superhelicity is sufficient to induce the B-Z transition in the presence of low tensionFolding and unfolding single RNA molecules under tension.Free energy calculations reveal rotating-ratchet mechanism for DNA supercoil relaxation by topoisomerase IB and its inhibition.A Coarse-Grained Model of Unstructured Single-Stranded DNA Derived from Atomistic Simulation and Single-Molecule Experiment.Robust processivity of myosin V under off-axis loads.Efficient preparation of internally modified single-molecule constructs using nicking enzymes.RNA reactions one molecule at a timeMapping of single-base differences between two DNA strands in a single molecule using holliday junction nanomechanicsSimultaneous single-molecule measurements of phage T7 replisome composition and function reveal the mechanism of polymerase exchangeSeeing a molecular machine self-renew.Revisiting the central dogma one molecule at a time.Do-it-yourself guide: how to use the modern single-molecule toolkitForcing a connection: impacts of single-molecule force spectroscopy on in vivo tension sensing.SSB functions as a sliding platform that migrates on DNA via reptation.Tethered fluorophore motion: studying large DNA conformational changes by single-fluorophore imagingAsymmetric unwrapping of nucleosomes under tension directed by DNA local flexibilityReal-time submillisecond single-molecule FRET dynamics of freely diffusing molecules with liposome tethering.Optical tweezers study life under tensionHexapeptides that inhibit processing of branched DNA structures induce a dynamic ensemble of Holliday junction conformations.Mechanical properties of DNA origami nanoassemblies are determined by Holliday junction mechanophores
P2860
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P2860
Fluorescence-force spectroscopy maps two-dimensional reaction landscape of the holliday junction.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Fluorescence-force spectroscop ...... cape of the holliday junction.
@ast
Fluorescence-force spectroscop ...... cape of the holliday junction.
@en
type
label
Fluorescence-force spectroscop ...... cape of the holliday junction.
@ast
Fluorescence-force spectroscop ...... cape of the holliday junction.
@en
prefLabel
Fluorescence-force spectroscop ...... cape of the holliday junction.
@ast
Fluorescence-force spectroscop ...... cape of the holliday junction.
@en
P2093
P2860
P356
P1433
P1476
Fluorescence-force spectroscop ...... cape of the holliday junction.
@en
P2093
David M J Lilley
Michelle K Nahas
Ruobo Zhou
Sungchul Hohng
Taekjip Ha
P2860
P304
P356
10.1126/SCIENCE.1146113
P407
P577
2007-10-01T00:00:00Z