The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.
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Topical insulin accelerates wound healing in diabetes by enhancing the AKT and ERK pathways: a double-blind placebo-controlled clinical trialNitric oxide synthases: regulation and functionThe insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endotheliumCavin-3 dictates the balance between ERK and Akt signaling.Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's disease.Long-term high-fat consumption leads to downregulation of Akt phosphorylation of eNOS at Ser1177 and upregulation of Sirtuin-1 expression in rat cavernous tissue.Time is of the essence: vascular implications of the circadian clock.Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates.Endothelial nitric oxide synthase transgenic models of endothelial dysfunctionDimethylarginine dimethylaminohydrolase 1 modulates endothelial cell growth through nitric oxide and AktUp-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function.Endothelial ephrin-B2 is essential for arterial vasodilation in mice.Bone morphogenetic protein receptor II is a novel mediator of endothelial nitric-oxide synthase activation.Priming of hypoxia-inducible factor by neuronal nitric oxide synthase is essential for adaptive responses to severe anemia.Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2eNOS Gene Variant in Patients with Coronary Artery Disease.Changing standard chow diet promotes vascular NOS dysfunction in Dahl S rats.Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice.VEGF-mediated phosphorylation of eNOS regulates angioblast and embryonic endothelial cell proliferationC-reactive protein causes insulin resistance in mice through Fcγ receptor IIB-mediated inhibition of skeletal muscle glucose delivery.Stromal cell-derived factor 2 is critical for Hsp90-dependent eNOS activation.VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread.Regulation of retinal angiogenesis by endothelial nitric oxide synthase signaling pathway.eNOS-derived nitric oxide regulates endothelial barrier function through VE-cadherin and Rho GTPases.Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways.Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice.Interactions between nitric oxide and hypoxia-inducible factor signaling pathways in inflammatory diseaseUncoupling Caveolae From Intracellular Signaling In Vivo.Redox-sensitive mechanisms underlying vascular dysfunction in heart failure.Compartmentalized nitric oxide signaling in the resistance vasculatureeNOS phosphorylation on serine 1176 affects insulin sensitivity and adiposity.Requirement of phosphorylatable endothelial nitric oxide synthase at Ser-1177 for vasoinhibin-mediated inhibition of endothelial cell migration and proliferation in vitro.Nongenomic thyroid hormone signaling occurs through a plasma membrane-localized receptor.Protein kinase D activity controls endothelial nitric oxide synthesis.Erythropoietin enhances mitochondrial biogenesis in cardiomyocytes exposed to chronic hypoxia through Akt/eNOS signalling pathway.Regulation of arterial blood pressure by Akt1-dependent vascular relaxation.Lipoteichoic acid-deficientLactobacillus acidophilusregulates downstream signals
P2860
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P2860
The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.
@ast
The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.
@en
type
label
The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.
@ast
The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.
@en
prefLabel
The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.
@ast
The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.
@en
P2093
P2860
P1433
P1476
The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo.
@en
P2093
Annarita Di Lorenzo
Berhad Derakhshan
Dimitriy Atochin
Kenneth D Harrison
Michael Schleicher
Paul L Huang
Satoshi Kashiwagi
Takahisa Murata
P2860
P356
10.1126/SCISIGNAL.2000343
P577
2009-08-04T00:00:00Z