Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
about
LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6Oxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's diseaseErythropoietin: new directions for the nervous systemTargeting disease through novel pathways of apoptosis and autophagyUncovering novel actors in astrocyte-neuron crosstalk in Parkinson's disease: the Wnt/β-catenin signaling cascade as the common final pathway for neuroprotection and self-repairThe regulation and deregulation of Wnt signaling by PARK genes in health and diseaseWnt your brain be inflamed? Yes, it Wnt!GSK-3β dysregulation contributes to parkinson's-like pathophysiology with associated region-specific phosphorylation and accumulation of tau and α-synucleinSpatio-temporal expression pattern of frizzled receptors after contusive spinal cord injury in adult ratsDiversity matters - heterogeneity of dopaminergic neurons in the ventral mesencephalon and its relation to Parkinson's DiseaseThe importance of Wnt signalling for neurodegeneration in Parkinson's diseaseNovel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of AssaysA Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotectionDepletion of canonical Wnt signaling components has a neuroprotective effect on midbrain dopaminergic neurons in an MPTP-induced mouse model of Parkinson's diseaseProtective LRRK2 R1398H Variant Enhances GTPase and Wnt Signaling Activity.Activated astrocytes enhance the dopaminergic differentiation of stem cells and promote brain repair through bFGFA yeast two-hybrid screen reveals that osteopontin associates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain.ERKed by LRRK2: a cell biological perspective on hereditary and sporadic Parkinson's disease.Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease.Pentazocine Protects SN4741 Cells Against MPP+-Induced Cell Damage via Up-Regulation of the Canonical Wnt/β-Catenin Signaling Pathway.Differential expression of Wnts after spinal cord contusion injury in adult rats.WISP1: Clinical insights for a proliferative and restorative member of the CCN familyEnhancing Beta-Catenin Activity via GSK3beta Inhibition Protects PC12 Cells against Rotenone Toxicity through Nurr1 Induction.EPO relies upon novel signaling of Wnt1 that requires Akt1, FoxO3a, GSK-3β, and β-catenin to foster vascular integrity during experimental diabetes.Activation of Wnt/β-catenin signaling in Muller glia protects photoreceptors in a mouse model of inherited retinal degeneration.Progranulin gene delivery protects dopaminergic neurons in a mouse model of Parkinson's disease.Erythropoietin and Wnt1 govern pathways of mTOR, Apaf-1, and XIAP in inflammatory microglia.Wnt1 inducible signaling pathway protein 1 (WISP1) blocks neurodegeneration through phosphoinositide 3 kinase/Akt1 and apoptotic mitochondrial signaling involving Bad, Bax, Bim, and Bcl-xLPrevention of β-amyloid degeneration of microglia by erythropoietin depends on Wnt1, the PI 3-K/mTOR pathway, Bad, and Bcl-xL.WISP1 (CCN4) autoregulates its expression and nuclear trafficking of β-catenin during oxidant stress with limited effects upon neuronal autophagy.GSK-3β-induced Tau pathology drives hippocampal neuronal cell death in Huntington's disease: involvement of astrocyte-neuron interactionsWnt Signaling Alteration in the Spinal Cord of Amyotrophic Lateral Sclerosis Transgenic Mice: Special Focus on Frizzled-5 Cellular Expression PatternG-protein-coupled receptors in adult neurogenesis.Increased blood-cerebrospinal fluid transfer of albumin in advanced Parkinson's disease.Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascadePrimary cultures of astrocytes: their value in understanding astrocytes in health and disease.Plasticity of subventricular zone neuroprogenitors in MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease involves cross talk between inflammatory and Wnt/β-catenin signaling pathways: functional consequences for nAging-induced Nrf2-ARE pathway disruption in the subventricular zone drives neurogenic impairment in parkinsonian mice via PI3K-Wnt/β-catenin dysregulation.Nurr1-Based Therapies for Parkinson's Disease.LRRK2: an éminence grise of Wnt-mediated neurogenesis?
P2860
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P2860
Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Reactive astrocytes and Wnt/β- ...... model of Parkinson's disease.
@ast
Reactive astrocytes and Wnt/β- ...... model of Parkinson's disease.
@en
type
label
Reactive astrocytes and Wnt/β- ...... model of Parkinson's disease.
@ast
Reactive astrocytes and Wnt/β- ...... model of Parkinson's disease.
@en
prefLabel
Reactive astrocytes and Wnt/β- ...... model of Parkinson's disease.
@ast
Reactive astrocytes and Wnt/β- ...... model of Parkinson's disease.
@en
P2093
P2860
P1476
Reactive astrocytes and Wnt/β- ...... model of Parkinson's disease.
@en
P2093
A E C Ihekwaba
B Marchetti
C Cossetti
D Franciotta
F L'Episcopo
L Andreoni
M C Morale
P2860
P304
P356
10.1016/J.NBD.2010.10.023
P577
2010-11-05T00:00:00Z