Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells
about
DNA damage, homology-directed repair, and DNA methylationThe SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repairOverexpression of human RAD51 and RAD52 reduces double-strand break-induced homologous recombination in mammalian cellsThe BRCA2-interacting protein BCCIP functions in RAD51 and BRCA2 focus formation and homologous recombinational repairXRCC3 promotes homology-directed repair of DNA damage in mammalian cellsDeficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joiningATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2Recombinational DNA Repair in Cancer and Normal Cells: The Challenge of Functional AnalysisThe accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cellsOrigins of chromosomal rearrangement hotspots in the human genome: evidence from the AZFa deletion hotspotsGene conversion and deletion frequencies during double-strand break repair in human cells are controlled by the distance between direct repeatsIn vivo selection of engineered homing endonucleases using double-strand break induced homologous recombinationNovel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET RadiationTowards a new era in medicine: therapeutic genome editingMolecular basis of engineered meganuclease targeting of the endogenous human RAG1 locusRepair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cellsCapture of DNA sequences at double-strand breaks in mammalian chromosomesInterchromosomal gene conversion at an endogenous human cell locusNuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damageTriplex-induced recombination in human cell-free extracts. Dependence on XPA and HsRad51.Targeted engineering of the Caenorhabditis elegans genome following Mos1-triggered chromosomal breaksEvidence for a fast, intrachromosomal conversion mechanism from mapping of nucleotide variants within a homogeneous alpha-satellite DNA array.Regulation of double-strand break-induced mammalian homologous recombination by UBL1, a RAD51-interacting proteinRosa26-GFP direct repeat (RaDR-GFP) mice reveal tissue- and age-dependence of homologous recombination in mammals in vivo.Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cellsChromosome breaks and genomic instability.Promiscuous patching of broken chromosomes in mammalian cells with extrachromosomal DNA.Multiple pathways for repair of DNA double-strand breaks in mammalian chromosomesA double-strand break in a chromosomal LINE element can be repaired by gene conversion with various endogenous LINE elements in mouse cellsGene conversion tracts from double-strand break repair in mammalian cells.DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination.miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase.BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair.Triplex technology in studies of DNA damage, DNA repair, and mutagenesisManipulating the mammalian genome by homologous recombinationTranscription of a donor enhances its use during double-strand break-induced gene conversion in human cellsGenomic deletions of the Drosophila melanogaster Hsp70 genesMultiple heterologies increase mitotic double-strand break-induced allelic gene conversion tract lengths in yeast.Long inverted repeats are an at-risk motif for recombination in mammalian cells.Homologous recombinational repair of double-strand breaks in yeast is enhanced by MAT heterozygosity through yKU-dependent and -independent mechanisms.
P2860
Q21092492-DACB79EF-A52F-4D69-BBB4-09DFC786044FQ24298284-28E6AE39-8F27-4E27-ABE7-7AC8E5960EFEQ24555124-5C5E10B7-D882-42AD-BF7E-DA0F185DF97DQ24556631-4D20641D-BABE-41D1-A622-8D7222883A9BQ24597771-8F16F84C-46A3-4C04-B2EE-EC07DA489F5AQ24630418-2D775596-5AAF-40AE-B089-85AC0A54ACAFQ24647310-A61A6ECD-B67B-4B28-A94E-D3A47DF9F85CQ24680716-B5181B23-4265-404F-B09C-703389063893Q24794005-3C524F47-6969-490B-9DE4-6C3BE7C87219Q24797585-DBB5B949-4EEE-4A9D-82C9-94696049A236Q24803093-5C2DDC81-65F8-47D9-8A5C-6940F5FCD58CQ24811303-C0FDF15C-AF1F-4592-AE71-19F33CE9BE76Q26742111-91FE0DAD-E57F-4BAD-B24B-59EE12E44670Q26773287-C25CEA6A-E063-4C87-B1EA-B7BACB1FFCC5Q27664531-6164BC8F-1B60-4F0E-A2CD-B5BD96527169Q28209896-D26055EB-5830-4D93-B3D3-084E07DD5ECBQ28346450-0149B8F1-59F8-43B3-8FDB-60C8D02279D0Q28366744-5BFDA477-F5B9-487E-AD16-6920DE84F330Q28610023-4772AC39-B186-4164-9EF6-1518B37870EFQ30661706-14F86206-992B-4DD1-8FB8-745DC3275DA6Q30828323-4AA30100-90D6-4141-8429-2FE56708CDF7Q30872875-ABCF02E2-FD41-4E23-9F1E-AE70C67BF6CCQ33615409-09120687-A5AE-46BC-A059-D4E8D336E01EQ33716551-2CC7E2E7-572B-42CA-B012-7A606FE3884CQ33774945-92C66BA5-562E-41E5-9299-271BC37B1A33Q33853722-A16F77D8-8163-45E8-8D1B-FFBBFB732C52Q33948430-BF137D25-336E-4C01-B7C4-71AF00225DE2Q33960694-CA8C861A-C215-4717-B37A-B365016CBC56Q33961192-07CD3757-38E4-4EC1-8BB0-9408A6665343Q33995776-037890A6-940C-49AA-94C8-29971C535D23Q34020119-14D74142-1B95-4372-9299-C2B4FB27F118Q34043212-E5F7EAE7-F881-4260-B0CB-1EEB8438D549Q34110729-B708B97D-7ECE-4908-8DCC-BF756BEA714AQ34179182-69AD60C4-B72C-4BE7-A6F5-8A1A2DAC7E36Q34311686-12C80E60-D2CC-4239-AA84-05D4CB72AB54Q34563172-D524868A-D408-4B31-8A50-45BFA3594F89Q34569662-82FA2D11-2D3C-4DEA-B8F1-38B7EE1B1D78Q34607778-030AB3C4-781B-450F-8EDD-AF847741AB41Q34608413-5C1238D5-BC62-4E53-992E-70315552E806Q34611935-862ED3FE-8CB4-4400-8C34-9B071D93443F
P2860
Chromosomal double-strand breaks induce gene conversion at high frequency in mammalian cells
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Chromosomal double-strand brea ...... h frequency in mammalian cells
@ast
Chromosomal double-strand brea ...... h frequency in mammalian cells
@en
type
label
Chromosomal double-strand brea ...... h frequency in mammalian cells
@ast
Chromosomal double-strand brea ...... h frequency in mammalian cells
@en
prefLabel
Chromosomal double-strand brea ...... h frequency in mammalian cells
@ast
Chromosomal double-strand brea ...... h frequency in mammalian cells
@en
P2860
P356
P1476
Chromosomal double-strand brea ...... h frequency in mammalian cells
@en
P2093
D G Taghian
J A Nickoloff
P2860
P304
P356
10.1128/MCB.17.11.6386
P407
P577
1997-11-01T00:00:00Z