Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method.
about
Small toxic protein encoded on chromosome VII of Saccharomyces cerevisiaeThe Carboxy-Terminal Tails of Septins Cdc11 and Shs1 Recruit Myosin-II Binding Factor Bni5 to the Bud Neck in Saccharomyces cerevisiae.Purifying Selection Maintains Dosage-Sensitive Genes during Degeneration of the Threespine Stickleback Y ChromosomePremature termination of GAT1 transcription explains paradoxical negative correlation between nitrogen-responsive mRNA, but constitutive low-level protein productionElectrostatic mis-interactions cause overexpression toxicity of proteins in E. coliEvaluating the fitness cost of protein expression in Saccharomyces cerevisiae.Evaluation of the lower protein limit in the budding yeast Saccharomyces cerevisiae using TIPI-gTOW.Aneuploid proliferation defects in yeast are not driven by copy number changes of a few dosage-sensitive genes.Dosage compensation can buffer copy-number variation in wild yeastHigh-Throughput Identification of Adaptive Mutations in Experimentally Evolved Yeast Populations.Post-Translational Dosage Compensation Buffers Genetic Perturbations to Stoichiometry of Protein Complexes.Quantitative nature of overexpression experiments.Chromosome-Specific and Global Effects of Aneuploidy in Saccharomyces cerevisiaeTransient protein-protein interactions perturb E. coli metabolome and cause gene dosage toxicity.Accumulation of Deleterious Mutations on the Neo-Y Chromosome of Japan Sea Stickleback (Gasterosteus nipponicus).Engineering tolerance to industrially relevant stress factors in yeast cell factories.Network analyses based on comprehensive molecular interaction maps reveal robust control structures in yeast stress response pathways.The inhibitory mechanism of Hal3 on the yeast Ppz1 phosphatase: A mutagenesis analysisCellular growth defects triggered by an overload of protein localization processes.Dosage-sensitive genes in evolution and disease.A Concentration-Dependent Liquid Phase Separation Can Cause Toxicity upon Increased Protein Expression.Genome-wide construction of a series of designed segmental aneuploids in Saccharomyces cerevisiae.Partial dispensability of Djp1's J domain in peroxisomal protein import in Saccharomyces cerevisiae results from genetic redundancy with another class II J protein, Caj1.Modeling the contributions of chromosome segregation errors and aneuploidy to Saccharomyces hybrid sterility.Fitness Effects of Cis-Regulatory Variants in the Saccharomyces cerevisiae TDH3 Promoter.Novel tRNA function in amino acid sensing of yeast Tor complex1.Hsp70-associated chaperones have a critical role in buffering protein production costs.Assessing phagotrophy in the mixotrophic ciliate Paramecium bursaria using GFP-expressing yeast cells.Functional diversification accompanies gene family expansion of MED2 homologs in Candida albicans.Stoichiometric balance of protein copy numbers is measurable and functionally significant in a protein-protein interaction network for yeast endocytosis.Rapid regulatory evolution of a nonrecombining autosome linked to divergent behavioral phenotypes.High-dimensional single-cell phenotyping reveals extensive haploinsufficiency.Estimating the protein burden limit of yeast cells by measuring the expression limits of glycolytic proteinsReaching the limit
P2860
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P2860
Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Identification of dosage-sensi ...... the genetic tug-of-war method.
@ast
Identification of dosage-sensi ...... the genetic tug-of-war method.
@en
type
label
Identification of dosage-sensi ...... the genetic tug-of-war method.
@ast
Identification of dosage-sensi ...... the genetic tug-of-war method.
@en
prefLabel
Identification of dosage-sensi ...... the genetic tug-of-war method.
@ast
Identification of dosage-sensi ...... the genetic tug-of-war method.
@en
P2093
P2860
P356
P1433
P1476
Identification of dosage-sensi ...... the genetic tug-of-war method.
@en
P2093
Hiroaki Kitano
Koji Makanae
Reiko Kintaka
P2860
P304
P356
10.1101/GR.146662.112
P577
2012-12-28T00:00:00Z