A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease. - Wikidata - awgldk - TriplyDB

A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease.

A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease.

http://www.wikidata.org/entity/Q36580714

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Genetic and Transcriptomic Profiles of Inflammation in Neurodegenerative Diseases: Alzheimer, Parkinson, Creutzfeldt-Jakob and Tauopathies The role of the immune system in neurodegenerative disorders: Adaptive or maladaptive?Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death Systems biology of neurodegenerative diseases Using Gene Ontology to describe the role of the neurexin-neuroligin-SHANK complex in human, mouse and rat and its relevance to autism A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy Autoimmune antibody decline in Parkinson's disease and Multiple System Atrophy; a step towards immunotherapeutic strategies.Pathways to Parkinsonism Redux: convergent pathobiological mechanisms in genetics of Parkinson's disease.Role of α-synuclein in inducing innate and adaptive immunity in Parkinson disease.STK39, But Not BST1, HLA-DQB1, and SPPL2B Polymorphism, Is Associated With Han-Chinese Parkinson's Disease in Taiwan.Parkinson's disease-associated genetic variation is linked to quantitative expression of inflammatory genes.Polygenic risk of Parkinson disease is correlated with disease age at onset.Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease.Inflammatory profile in LRRK2-associated prodromal and clinical PD Using the Gene Ontology to Annotate Key Players in Parkinson's Disease The Evolution of Genetics: Alzheimer's and Parkinson's Diseases.Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases.Association studies of sporadic Parkinson's disease in the genomic era.Parkinson's disease: an update on pathogenesis and treatment.The role of inflammation in sporadic and familial Parkinson's disease.Recent advances in Parkinson’s disease genetics.Neuropathology of α-synuclein propagation and braak hypothesis.Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases.Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model.Microglia and C9orf72 in neuroinflammation and ALS and frontotemporal dementia.NADPH oxidases in Parkinson's disease: a systematic review.Inflammatory profile discriminates clinical subtypes in LRRK2-associated Parkinson's disease.From Genomics to Omics Landscapes of Parkinson's Disease: Revealing the Molecular Mechanisms.Parkinson's disease: From human genetics to clinical trials.Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines.Abnormalities of age-related T cell senescence in Parkinson's disease.Linking Neuroinflammation and Neurodegeneration in Parkinson's Disease.A monocyte gene expression signature in the early clinical course of Parkinson's disease Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells The Challenge of the Pathogenesis of Parkinson's Disease: Is Autoimmunity the Culprit?

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P2860

A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease.

http://www.wikidata.org/entity/Q36580714

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

A pathway-based analysis provi ...... bility to Parkinson's disease.

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A pathway-based analysis provi ...... bility to Parkinson's disease.

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A pathway-based analysis provi ...... bility to Parkinson's disease.

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A pathway-based analysis provi ...... bility to Parkinson's disease.

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A pathway-based analysis provi ...... bility to Parkinson's disease.

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Human Molecular Genetics

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A pathway-based analysis provi ...... bility to Parkinson's disease.

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P2093

Alexey Vedernikov

http://www.w3.org/2001/XMLSchema#string

Dena Hernandez

http://www.w3.org/2001/XMLSchema#string

Francesco Bettella

http://www.w3.org/2001/XMLSchema#string

Hreinn Stefánsson

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J Raphael Gibbs

http://www.w3.org/2001/XMLSchema#string

Javier Simón-Sánchez

http://www.w3.org/2001/XMLSchema#string

Kari Majamaa

http://www.w3.org/2001/XMLSchema#string

Lesley Jones

http://www.w3.org/2001/XMLSchema#string

Manu Sharma

http://www.w3.org/2001/XMLSchema#string

Michael A Nalls

http://www.w3.org/2001/XMLSchema#string

P2860

A two-stage meta-analysis identifies several new loci for Parkinson's disease

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

A genomic pathway approach to a complex disease: axon guidance and Parkinson disease

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation

Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kappaB signaling

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

High-resolution whole-genome association study of Parkinson disease.

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1039-1049

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scholarly article

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10.1093/HMG/DDS492

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5

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22

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Claudia Schulte

Nicholas W. Wood

Andrew Singleton

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2012-12-07T00:00:00Z

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23223016

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P921

Parkinson's disease

P932

3561909

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