Detecting and characterizing reactive metabolites by liquid chromatography/tandem mass spectrometry.
about
Metabolic activation of the antibacterial agent triclocarban by cytochrome P450 1A1 yielding glutathione adductsHigh-performance liquid chromatography-tandem mass spectrometry in the identification and determination of phase I and phase II drug metabolites.High-resolution chromatography/time-of-flight MSE with in silico data mining is an information-rich approach to reactive metabolite screening.Application of LC-high-resolution MS with 'intelligent' data mining tools for screening reactive drug metabolites.Mapping serum albumin adducts of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by data-dependent tandem mass spectrometry.Profiling the reactive metabolites of xenobiotics using metabolomic technologiesCYP3A4-mediated lopinavir bioactivation and its inhibition by ritonavir.Detection of reactive metabolites using isotope-labeled glutathione trapping and simultaneous neutral loss and precursor ion scanning with ultra-high-pressure liquid chromatography triple quadruple mass spectrometryIrreversible binding of an anticancer compound (BI-94) to plasma proteins.Modeling Reactivity to Biological Macromolecules with a Deep Multitask Network.A comprehensive workflow of mass spectrometry-based untargeted metabolomics in cancer metabolic biomarker discovery using human plasma and urineIn Vitro Enzyme Assay of CYP21A2 Mutation (R483Q) by A Novel Method Using Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry (LC-ESI-MS/MS).From known knowns to known unknowns: predicting in vivo drug metabolites.Bioactivation of herbal constituents: simple alerts in the complex system.Peptide and protein drugs: the study of their metabolism and catabolism by mass spectrometry.In vitro metabolic fate of alizapride: evidence for the formation of reactive metabolites based on liquid chromatography-tandem mass spectrometry.Assessing covalent binding of reactive drug metabolites by complete protein digestion and LC-MS analysis.Nucleophile addition of reduced glutathione on 2-methyl-2-nitroso compound: a combined electron paramagnetic resonance spectroscopy and electrospray tandem mass spectrometry study.Using electron induced dissociation (EID) on an LC time-scale to characterize a mixture of analogous small organic molecules.Phase I and phase II reductive metabolism simulation of nitro aromatic xenobiotics with electrochemistry coupled with high resolution mass spectrometry.Rapid screening and characterization of glutathione-trapped reactive metabolites using a polarity switch-based approach on a high-resolution quadrupole orbitrap mass spectrometer.Identification and characterization of vilazodone metabolites in rats and microsomes by ultrahigh-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry.Acebutolol and alprenolol metabolism predictions: comparative study of electrochemical and cytochrome P450-catalyzed reactions using liquid chromatography coupled to high-resolution mass spectrometry.
P2860
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P2860
Detecting and characterizing reactive metabolites by liquid chromatography/tandem mass spectrometry.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Detecting and characterizing r ...... aphy/tandem mass spectrometry.
@ast
Detecting and characterizing r ...... aphy/tandem mass spectrometry.
@en
type
label
Detecting and characterizing r ...... aphy/tandem mass spectrometry.
@ast
Detecting and characterizing r ...... aphy/tandem mass spectrometry.
@en
prefLabel
Detecting and characterizing r ...... aphy/tandem mass spectrometry.
@ast
Detecting and characterizing r ...... aphy/tandem mass spectrometry.
@en
P356
P1476
Detecting and characterizing r ...... aphy/tandem mass spectrometry.
@en
P2093
Raju Subramanian
Shuguang Ma
P304
P356
10.1002/JMS.1098
P577
2006-09-01T00:00:00Z