Single-neuron sequencing analysis of L1 retrotransposition and somatic mutation in the human brain.
about
Retrotransposition of gene transcripts leads to structural variation in mammalian genomesSingle cell genomics: advances and future perspectives'There and back again': revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic eraeuL1db: the European database of L1HS retrotransposon insertions in humansDissecting genomic diversity, one cell at a timeRestricting retrotransposons: a reviewGuardian of the Human Genome: Host Defense Mechanisms against LINE-1 RetrotranspositionPost-Transcriptional Control of LINE-1 Retrotransposition by Cellular Host Factors in Somatic CellsTransposable elements in the mammalian embryo: pioneers surviving through stealth and serviceRoles for retrotransposon insertions in human diseaseSingle-cell transcriptome sequencing: recent advances and remaining challengesGenetic changes shaping the human brainSomatic mosaicism in the human genomeThe Influence of LINE-1 and SINE Retrotransposons on Mammalian Genomes"Seq-ing" insights into the epigenetics of neuronal gene regulationAdvances and applications of single-cell sequencing technologiesThe mind-brain relationship as a mathematical problemSomatic mosaicism: implications for disease and transmission geneticsThe role of transposable elements in health and diseases of the central nervous systemChromothripsis from DNA damage in micronuclei.Molecular epigenetic switches in neurodevelopment in health and diseaseRetrotransposons shape species-specific embryonic stem cell gene expressionThe aging clock and circadian control of metabolism and genome stabilityRegulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at nightChanging genetic paradigms: creating next-generation genetic databases as tools to understand the emerging complexities of genotype/phenotype relationshipsSingle-cell transcriptogenomics reveals transcriptional exclusion of ENU-mutated allelesL1 retrotransposons, cancer stem cells and oncogenesisSomatic mutation, genomic variation, and neurological diseasePostzygotic single-nucleotide mosaicisms in whole-genome sequences of clinically unremarkable individualsActivation of individual L1 retrotransposon instances is restricted to cell-type dependent permissive lociLINE-1 activity as molecular basis for genomic instability associated with light exposure at nightGenomic DNA transposition induced by human PGBD5Retrotransposition in tumors and brainsTransposable elements as genetic regulatory substrates in early developmentThe Microprocessor controls the activity of mammalian retrotransposonsFunctional impact of the human mobilomeMapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotranspositionTransposable elements re-wire and fine-tune the transcriptomeThe Complete Genome Sequences, Unique Mutational Spectra, and Developmental Potency of Adult Neurons Revealed by Cloning.Single neuron transcriptome analysis can reveal more than cell type classification: Does it matter if every neuron is unique?
P2860
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P2860
Single-neuron sequencing analysis of L1 retrotransposition and somatic mutation in the human brain.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Single-neuron sequencing analy ...... c mutation in the human brain.
@ast
Single-neuron sequencing analy ...... c mutation in the human brain.
@en
type
label
Single-neuron sequencing analy ...... c mutation in the human brain.
@ast
Single-neuron sequencing analy ...... c mutation in the human brain.
@en
prefLabel
Single-neuron sequencing analy ...... c mutation in the human brain.
@ast
Single-neuron sequencing analy ...... c mutation in the human brain.
@en
P2093
P2860
P1433
P1476
Single-neuron sequencing analy ...... c mutation in the human brain.
@en
P2093
Annapurna Poduri
Christopher A Walsh
Edward C Gilmore
Eunjung Lee
Gilad D Evrony
Hillel S Lehmann
J J Parker
Kutay D Atabay
L Benjamin Hills
Peter J Park
P2860
P304
P356
10.1016/J.CELL.2012.09.035
P407
P577
2012-10-01T00:00:00Z