CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging - Wikidata - awgldk - TriplyDB

CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging

CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging

http://www.wikidata.org/entity/Q36598397

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The choroid plexus-cerebrospinal fluid interface in Alzheimer's disease: more than just a barrier How do immune cells support and shape the brain in health, disease, and aging?Role of microglial m1/m2 polarization in relapse and remission of psychiatric disorders and diseases 'As above, so below' examining the interplay between emotion and the immune system.Ageing, neurodegeneration and brain rejuvenation Friend or foe: the dichotomous impact of T cells on neuro-de/re-generation during aging An in silico approach for modelling T-helper polarizing iNKT cell agonists Lymphatics in Neurological Disorders: A Neuro-Lympho-Vascular Component of Multiple Sclerosis and Alzheimer's Disease?Central Nervous System: (Immunological) Ivory Tower or Not?Interactions of innate and adaptive immunity in brain development and function.MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4.Brain antigen-reactive CD4+ T cells are sufficient to support learning behavior in mice with limited T cell repertoire.Learning and memory ... and the immune system.Ionizing Radiation-Induced Immune and Inflammatory Reactions in the Brain.Acrylamide exposure impairs blood-cerebrospinal fluid barrier function Altered activation of innate immunity associates with white matter volume and diffusion in first-episode psychosis.The Association of Cytokine Levels With Cognitive Function in Children With Sickle Cell Disease and Normal MRI Studies of the Brain Breaking immune tolerance by targeting Foxp3(+) regulatory T cells mitigates Alzheimer's disease pathology Complement and Humoral Adaptive Immunity in the Human Choroid Plexus: Roles for Stromal Concretions, Basement Membranes, and Epithelium Age-Associated Resident Memory CD8 T Cells in the Central Nervous System Are Primed To Potentiate Inflammation after Ischemic Brain Injury.Aging. Aging-induced type I interferon response at the choroid plexus negatively affects brain function.MCP-1 and eotaxin-1 selectively and negatively associate with memory in MCI and Alzheimer's disease dementia phenotypes.CD4(+) T Cell-Receptor Repertoire Diversity is Compromised in the Spleen but Not in the Bone Marrow of Aged Mice Due to Private and Sporadic Clonal Expansions.T Lymphocytes and Inflammatory Mediators in the Interplay between Brain and Blood in Alzheimer's Disease: Potential Pools of New Biomarkers.The choroid plexus as a site of damage in hemorrhagic and ischemic stroke and its role in responding to injury.The resolution of neuroinflammation in neurodegeneration: leukocyte recruitment via the choroid plexus.T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases.Regulation of the Neurodegenerative Process Associated to Parkinson's Disease by CD4+ T-cells.Pathological differences between white and grey matter multiple sclerosis lesions.The Choroid Plexus in Healthy and Diseased Brain.Immunosenescence of microglia and macrophages: impact on the ageing central nervous system.The effect of aging on brain barriers and the consequences for Alzheimer's disease development.Advances in understanding the pathogenesis of CNS acute lymphoblastic leukaemia and potential for therapy.Microbial Immuno-Communication in Neurodegenerative Diseases Cytokines in Machado Joseph Disease/Spinocerebellar Ataxia 3.Encapsulated Choroid Plexus Epithelial Cells Actively Protect Against Intrahippocampal Aβ-induced Long-Term Memory Dysfunction; Upregulation of Effective Neurogenesis with the Abrogated Apoptosis and Neuroinflammation.Insights into psychosis risk from leukocyte microRNA expression.CCL11 is increased in the CNS in chronic traumatic encephalopathy but not in Alzheimer's disease.IFN-γ-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair.The systemic environment: at the interface of aging and adult neurogenesis.

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CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging

http://www.wikidata.org/entity/Q36598397

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Proceedings of the National Academy of Sciences of the United States of America

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CNS-specific immunity at the c ...... h2 inflammation in brain aging

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Aleksandra Deczkowska

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Fernando Gomez-Pinilla

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Hilah Gal

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Ilan Vaknin

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Liora Cahalon

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Mark P Mattson

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Michal Cardon

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Michal Schwartz

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Nataly Mirlas-Neisberg

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Nir Friedman

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P2860

Lung epithelial barrier function and wound healing are decreased by IL-4 and IL-13 and enhanced by IFN-gamma

T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions.

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

From inflammation to sickness and depression: when the immune system subjugates the brain

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

Arginase and pulmonary diseases

IL-4 attenuates the neuroinflammation induced by amyloid-beta in vivo and in vitro

Central memory and effector memory T cell subsets: function, generation, and maintenance

Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

Inflammation is detrimental for neurogenesis in adult brain

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2264-2269

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Aleksandra Deczkowska

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2013-01-18T00:00:00Z

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234704303

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23335631

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