Computational design of water-soluble analogues of the potassium channel KcsA
about
Design of protein-ligand binding based on the molecular-mechanics energy modelMembrane proteins: always an insoluble problem?NMR studies of a channel protein without membranes: Structure and dynamics of water-solubilized KcsANMR structure and dynamics of a designed water-soluble transmembrane domain of nicotinic acetylcholine receptorComputational redesign of the lipid-facing surface of the outer membrane protein OmpA.Structure of anti-FLAG M2 Fab domain and its use in the stabilization of engineered membrane proteins.The Framework of Computational Protein Design.Achievements and Challenges in Computational Protein Design.Protein engineering methods applied to membrane protein targets.A computationally designed water-soluble variant of a G-protein-coupled receptor: the human mu opioid receptor.Statistical theory for protein ensembles with designed energy landscapes.Scalable production of highly sensitive nanosensors based on graphene functionalized with a designed G protein-coupled receptor.Solubilization of a membrane protein by combinatorial superchargingComputational protein design: engineering molecular diversity, nonnatural enzymes, nonbiological cofactor complexes, and membrane proteins.Computational design of membrane proteins.Coarse-grained molecular dynamics of tetrameric transmembrane peptide bundles within a lipid bilayer.RosettaRemodel: a generalized framework for flexible backbone protein design.Characterization of a computationally designed water-soluble human μ-opioid receptor variant using available structural informationMolecular Dynamics Simulation of WSK-3, a Computationally Designed, Water-Soluble Variant of the Integral Membrane Protein KcsADesign, purification and characterization of a soluble variant of the integral membrane protein MotB for structural studiesComputational protein design: Advances in the design and redesign of biomolecular nanostructuresComputational design and selections for an engineered, thermostable terpene synthase.Making water-soluble integral membrane proteins in vivo using an amphipathic protein fusion strategy.Fluorescence correlation spectroscopic study of serpin depolymerization by computationally designed peptides.In silico protein design by combinatorial assembly of protein building blocksComputational de novo design and characterization of a protein that selectively binds a highly hyperpolarizable abiological chromophore.X-ray vs. NMR structures as templates for computational protein design.Amino acid contribution to protein solubility: Asp, Glu, and Ser contribute more favorably than the other hydrophilic amino acids in RNase Sa.Synthetic and natural consensus design for engineering charge within an affibody targeting epidermal growth factor receptor.Computational design and experimental characterization of peptides intended for pH-dependent membrane insertion and pore formationModeling backbone flexibility to achieve sequence diversity: the design of novel alpha-helical ligands for Bcl-xL.Rational design of new binding specificity by simultaneous mutagenesis of calmodulin and a target peptideSolubilization and humanization of paraoxonase-1Recent Advances in the Application of Solution NMR Spectroscopy to Multi-Span Integral Membrane Proteins.Development of a rotamer library for use in beta-peptide foldamer computational design.Rational design of DNA sequence-specific zinc fingers.Cascaded walks in protein sequence space: use of artificial sequences in remote homology detection between natural proteins.A water-soluble DsbB variant that catalyzes disulfide-bond formation in vivo.Production of Computationally Designed Small Soluble- and Membrane-Proteins: Cloning, Expression, and Purification.De novo design of a pentameric coiled-coil: decoding the motif for tetramer versus pentamer formation in water-soluble phospholamban.
P2860
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P2860
Computational design of water-soluble analogues of the potassium channel KcsA
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Computational design of water-soluble analogues of the potassium channel KcsA
@ast
Computational design of water-soluble analogues of the potassium channel KcsA
@en
type
label
Computational design of water-soluble analogues of the potassium channel KcsA
@ast
Computational design of water-soluble analogues of the potassium channel KcsA
@en
prefLabel
Computational design of water-soluble analogues of the potassium channel KcsA
@ast
Computational design of water-soluble analogues of the potassium channel KcsA
@en
P2093
P2860
P356
P1476
Computational design of water-soluble analogues of the potassium channel KcsA
@en
P2093
Avram M Slovic
Hidetoshi Kono
James D Lear
P2860
P304
P356
10.1073/PNAS.0306417101
P407
P577
2004-02-06T00:00:00Z