Stop that cell! Beta-arrestin-dependent chemotaxis: a tale of localized actin assembly and receptor desensitization.
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G protein-coupled receptor kinase 2 positively regulates epithelial cell migrationFunctional specialization of beta-arrestin interactions revealed by proteomic analysisBeta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7Beta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transductionMoving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytesChemotactic migration of T cells towards dendritic cells promotes the detection of rare antigensThe type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42.beta-Arrestins scaffold cofilin with chronophin to direct localized actin filament severing and membrane protrusions downstream of protease-activated receptor-2.Phosphorylation of chemoattractant receptors regulates chemotaxis, actin reorganization and signal relay.Arrestins function in cAR1 GPCR-mediated signaling and cAR1 internalization in the development of Dictyostelium discoideum.βArrestin1 regulates the guanine nucleotide exchange factor RasGRF2 expression and the small GTPase Rac-mediated formation of membrane protrusion and cell motility.β-Arrestin 1 inhibits the GTPase-activating protein function of ARHGAP21, promoting activation of RhoA following angiotensin II type 1A receptor stimulation.A chemical biology approach demonstrates G protein βγ subunits are sufficient to mediate directional neutrophil chemotaxis.Prostaglandin E2 promotes lung cancer cell migration via EP4-betaArrestin1-c-Src signalsome.Beyond desensitization: physiological relevance of arrestin-dependent signaling.Identification of receptor binding-induced conformational changes in non-visual arrestins.Role for β-arrestin in mediating paradoxical β2AR and PAR2 signaling in asthma.Nonhematopoietic β-Arrestin-1 inhibits inflammation in a murine model of polymicrobial sepsis.Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).Apical and basolateral pools of proteinase-activated receptor-2 direct distinct signaling events in the intestinal epithelium.Heterotrimeric Gα(i) proteins are regulated by lipopolysaccharide and are anti-inflammatory in endotoxemia and polymicrobial sepsisActin dynamics is rapidly regulated by the PTEN and PIP2 signaling pathways leading to myocyte hypertrophy.β-arrestin2 in infiltrated macrophages inhibits excessive inflammation after myocardial infarctionRecent advances on the δ opioid receptor: from trafficking to function.S-nitrosylation-regulated GPCR signaling.Differential expression of arrestins is a predictor of breast cancer progression and survival.Cell, isoform, and environment factors shape gradients and modulate chemotaxisSystems biology approaches for understanding cellular mechanisms of immunity in lymph nodes during infectionGenetic Deletion of β-Arrestin-2 and the Mitigation of Established Airway Hyperresponsiveness in a Murine Asthma Modelβ-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway.Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activationTherapeutic potential of β-arrestin- and G protein-biased agonists.β-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivobeta-Arrestin 2: a Negative Regulator of Inflammatory Responses in Polymorphonuclear Leukocytes.Gene dosage-dependent negative regulatory role of β-arrestin-2 in polymicrobial infection-induced inflammation.Select G-protein-coupled receptors modulate agonist-induced signaling via a ROCK, LIMK, and β-arrestin 1 pathway.Proteoglycan signaling co-receptors: roles in cell adhesion, migration and invasion.beta-Adrenoceptor inverse agonists in asthmaThe complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targetsβ-Arrestins in the immune system
P2860
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P2860
Stop that cell! Beta-arrestin-dependent chemotaxis: a tale of localized actin assembly and receptor desensitization.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Stop that cell! Beta-arrestin- ...... and receptor desensitization.
@ast
Stop that cell! Beta-arrestin- ...... and receptor desensitization.
@en
type
label
Stop that cell! Beta-arrestin- ...... and receptor desensitization.
@ast
Stop that cell! Beta-arrestin- ...... and receptor desensitization.
@en
prefLabel
Stop that cell! Beta-arrestin- ...... and receptor desensitization.
@ast
Stop that cell! Beta-arrestin- ...... and receptor desensitization.
@en
P1476
Stop that cell! Beta-arrestin- ...... and receptor desensitization.
@en
P2093
Kathryn A DeFea
P304
P356
10.1146/ANNUREV.PHYSIOL.69.022405.154804
P577
2007-01-01T00:00:00Z