Transmitted/founder and chronic HIV-1 envelope proteins are distinguished by differential utilization of CCR5.
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Identifying Recent HIV Infections: From Serological Assays to GenomicsHIV-1 envelope-receptor interactions required for macrophage infection and implications for current HIV-1 cure strategiesOrigin of the transmitted virus in HIV infection: infected cells versus cell-free virusBottlenecks in HIV-1 transmission: insights from the study of founder virusesDifferences in the Selection Bottleneck between Modes of Sexual Transmission Influence the Genetic Composition of the HIV-1 Founder VirusCellular superspreaders: an epidemiological perspective on HIV infection inside the bodyRecent Insights into the HIV/AIDS Pandemic.Induction of a Tier-1-like Phenotype in Diverse Tier-2 Isolates by Agents that Guide HIV-1 Env to Perturbation-sensitive, Non-native States.A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity.Antigenicity-defined conformations of an extremely neutralization-resistant HIV-1 envelope spike.Which Antibody Functions are Important for an HIV Vaccine?Broadly neutralizing antibody VRC01 prevents HIV-1 transmission from plasmacytoid dendritic cells to CD4 T lymphocytes.Defining differential genetic signatures in CXCR4- and the CCR5-utilizing HIV-1 co-linear sequences.Mucosal immunity in the female genital tract, HIV/AIDSPhenotypic properties of transmitted founder HIV-1Distinct HIV-1 entry phenotypes are associated with transmission, subtype specificity, and resistance to broadly neutralizing antibodies.Characterization of HIV-1 envelopes in acutely and chronically infected injection drug usersSelection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteinsMacrophage infection via selective capture of HIV-1-infected CD4+ T cells.Immune evasion activities of accessory proteins Vpu, Nef and Vif are conserved in acute and chronic HIV-1 infection.Production of Mucosally Transmissible SHIV Challenge Stocks from HIV-1 Circulating Recombinant Form 01_AE env SequencesAnalysis of Viral Diversity in Relation to the Recency of HIV-1C Infection in BotswanaDelineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality.Accurate predictions of population-level changes in sequence and structural properties of HIV-1 Env using a volatility-controlled diffusion model.Signatures in Simian Immunodeficiency Virus SIVsmE660 Envelope gp120 Are Associated with Mucosal Transmission but Not Vaccination Breakthrough in Rhesus MacaquesA Novel Role for the Receptor of the Complement Cleavage Fragment C5a, C5aR1, in CCR5-Mediated Entry of HIV into Macrophages.Use of G-protein-coupled and -uncoupled CCR5 receptors by CCR5 inhibitor-resistant and -sensitive human immunodeficiency virus type 1 variants.Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design.Lack of prophylactic efficacy of oral maraviroc in macaques despite high drug concentrations in rectal tissuesLinkages between HIV-1 specificity for CCR5 or CXCR4 and in vitro usage of alternative coreceptors during progressive HIV-1 subtype C infection.Frequency and Env determinants of HIV-1 subtype C strains from antiretroviral therapy-naive subjects that display incomplete inhibition by maraviroc.HIV-1 envelope replication and α4β7 utilization among newly infected subjects and their corresponding heterosexual partners.Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitnessQuantifying CD4/CCR5 Usage Efficiency of HIV-1 Env Using the Affinofile System.Establishment of mouse leukemia cell lines expressing human CD4/CCR5 using lentiviral vectors.Development of SHIVs with circulating, transmitted HIV-1 variants.The HIV-1 transmission bottleneck.Nonhuman Primate Models and Understanding the Pathogenesis of HIV Infection and AIDS.HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G.Evolutionary view of the AIDS process
P2860
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P2860
Transmitted/founder and chronic HIV-1 envelope proteins are distinguished by differential utilization of CCR5.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Transmitted/founder and chroni ...... ferential utilization of CCR5.
@ast
Transmitted/founder and chroni ...... ferential utilization of CCR5.
@en
type
label
Transmitted/founder and chroni ...... ferential utilization of CCR5.
@ast
Transmitted/founder and chroni ...... ferential utilization of CCR5.
@en
prefLabel
Transmitted/founder and chroni ...... ferential utilization of CCR5.
@ast
Transmitted/founder and chroni ...... ferential utilization of CCR5.
@en
P2093
P2860
P50
P356
P1433
P1476
Transmitted/founder and chroni ...... ferential utilization of CCR5.
@en
P2093
Chuka A Didigu
Fang-Hua Lee
John P Moore
Kelechi C Chikere
Per Johan Klasse
Reem Berro
Robert W Doms
Shilpa S Iyer
Zahra F Parker
P2860
P304
P356
10.1128/JVI.02964-12
P407
P577
2012-12-26T00:00:00Z