Carbonyl reductases: the complex relationships of mammalian carbonyl- and quinone-reducing enzymes and their role in physiology.
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Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymesStructural basis for substrate specificity in human monomeric carbonyl reductasesGlutathione peroxidase inhibitory assay for electrophilic pollutants in diesel exhaust and tobacco smokeDetecting clusters of mutationsRoles of 3-nitrotyrosine- and 4-hydroxynonenal-modified brain proteins in the progression and pathogenesis of Alzheimer's disease.Biochemical characterization of TASSELSEED 2, an essential plant short-chain dehydrogenase/reductase with broad spectrum activities.Aging and luteinizing hormone effects on reactive oxygen species production and DNA damage in rat Leydig cells.Vasoactive Intestinal Peptide Knockout (VIP KO) mouse model of sulfite-sensitive asthma: up-regulation of novel lung carbonyl reductaseGlucose reintroduction triggers the activation of Nrf2 during experimental ischemia reperfusion.Hepatic response to oxidative injury in long-lived Ames dwarf miceTissue specific dysregulated protein subnetworks in type 2 diabetic bladder urothelium and detrusor muscleThe aldo-keto reductases (AKRs): Overview.Metabolism of doxorubicin to the cardiotoxic metabolite doxorubicinol is increased in a mouse model of chronic glutathione deficiency: A potential role for carbonyl reductase 3.A conserved antioxidant response element (ARE) in the promoter of human carbonyl reductase 3 (CBR3) mediates induction by the master redox switch Nrf2Metabolism of [6]-shogaol in mice and in cancer cells.SINGLET OXYGEN RESISTANT 1 links reactive electrophile signaling to singlet oxygen acclimation in Chlamydomonas reinhardtii.AS1DHRS4, a head-to-head natural antisense transcript, silences the DHRS4 gene cluster in cis and transSynthetic pathway for production of five-carbon alcohols from isopentenyl diphosphateOxidative stress contributes to liver damage in a murine model of alpha-1-antitrypsin deficiency.The JmjC domain histone demethylase Ndy1 regulates redox homeostasis and protects cells from oxidative stressMetabolism of ginger component [6]-shogaol in liver microsomes from mouse, rat, dog, monkey, and human.[10]-Gingerdiols as the major metabolites of [10]-gingerol in zebrafish embryos and in humans and their hematopoietic effects in zebrafish embryos.11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action.Pharmacokinetics of doxorubicin in pregnant women.High-throughput structural biology of metabolic enzymes and its impact on human diseases.4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: a toxic combination illuminated by redox proteomics studiesHuman microsomal carbonyl reducing enzymes in the metabolism of xenobiotics: well-known and promising members of the SDR superfamily.Carbonyl reduction pathways in drug metabolism.The modulation of carbonyl reductase 1 by polyphenols.Dysregulation of 11beta-hydroxysteroid dehydrogenases: implications during pregnancy and beyond.Prevalence of Non-Cytochrome P450-Mediated Metabolism in Food and Drug Administration-Approved Oral and Intravenous Drugs: 2006-2015.Phenotypic and metabolic investigation of a CSF-1R kinase receptor inhibitor (BLZ945) and its pharmacologically active metabolite.Mitochondria-targeted antioxidants protect pancreatic β-cells against oxidative stress and improve insulin secretion in glucotoxicity and glucolipotoxicity.Specificity of human aldo-keto reductases, NAD(P)H:quinone oxidoreductase, and carbonyl reductases to redox-cycle polycyclic aromatic hydrocarbon diones and 4-hydroxyequilenin-o-quinone.Transcriptional regulation of human and murine short-chain dehydrogenase/reductases (SDRs) - an in silico approach.The effectiveness of oracin in enhancing the cytotoxicity of doxorubicin through the inhibition of doxorubicin deactivation in breast cancer MCF7 cells.Effects of cigarette smoke, cessation and switching to a candidate modified risk tobacco product on the liver in Apoe -/- mice--a systems toxicology analysis.Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity.Identification of non-reported bupropion metabolites in human plasma.
P2860
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P2860
Carbonyl reductases: the complex relationships of mammalian carbonyl- and quinone-reducing enzymes and their role in physiology.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Carbonyl reductases: the compl ...... and their role in physiology.
@ast
Carbonyl reductases: the compl ...... and their role in physiology.
@en
type
label
Carbonyl reductases: the compl ...... and their role in physiology.
@ast
Carbonyl reductases: the compl ...... and their role in physiology.
@en
prefLabel
Carbonyl reductases: the compl ...... and their role in physiology.
@ast
Carbonyl reductases: the compl ...... and their role in physiology.
@en
P1476
Carbonyl reductases: the compl ...... and their role in physiology.
@en
P2093
Udo Oppermann
P304
P356
10.1146/ANNUREV.PHARMTOX.47.120505.105316
P577
2007-01-01T00:00:00Z