Glutamic acid 242 is a valve in the proton pump of cytochrome c oxidase.
about
Proton-pumping mechanism of cytochrome c oxidase: a kinetic master-equation approachSingle Enzyme Experiments Reveal a Long-Lifetime Proton Leak State in a Heme-Copper OxidaseA peroxide bridge between Fe and Cu ions in the O2 reduction site of fully oxidized cytochrome c oxidase could suppress the proton pumpRedox-Dependent Conformational Changes in Cytochrome c Oxidase Suggest a Gating Mechanism for Proton UptakeMolecular mechanisms for generating transmembrane proton gradientsProton-coupled electron transfer and the role of water molecules in proton pumping by cytochrome c oxidaseMicroscopic basis for kinetic gating in Cytochrome c oxidase: insights from QM/MM analysis.The alphabet of intrinsic disorder: II. Various roles of glutamic acid in ordered and intrinsically disordered proteins.Electrostatics, hydration, and proton transfer dynamics in the membrane domain of respiratory complex IExploration of the cytochrome c oxidase pathway puzzle and examination of the origin of elusive mutational effects.Cytochrome c oxidase: exciting progress and remaining mysteries.Insights into the mechanism of proton transport in cytochrome c oxidaseExpanding the view of proton pumping in cytochrome c oxidase through computer simulation.Interheme electron tunneling in cytochrome c oxidase.Theory of coupled electron and proton transfer reactions.Proton translocation in cytochrome c oxidase: insights from proton exchange kinetics and vibrational spectroscopy.Water molecule reorganization in cytochrome c oxidase revealed by FTIR spectroscopy.Glu-286 rotation and water wire reorientation are unlikely the gating elements for proton pumping in cytochrome C oxidase.Exploring the proton pump and exit pathway for pumped protons in cytochrome ba3 from Thermus thermophilus.Redox-induced activation of the proton pump in the respiratory complex I.Two tyrosyl radicals stabilize high oxidation states in cytochrome C oxidase for efficient energy conservation and proton translocation.Energetics and dynamics of proton transfer reactions along short water wires.EPR evidence of cyanide binding to the Mn(Mg) center of cytochrome c oxidase: support for Cu(A)-Mg involvement in proton pumpingProton transport pathway in the ClC Cl-/H+ antiporter.Kinetic gating of the proton pump in cytochrome c oxidase.Changing hydration level in an internal cavity modulates the proton affinity of a key glutamate in cytochrome c oxidase.Cytochrome c oxidase: Intermediates of the catalytic cycle and their energy-coupled interconversion.Coupled electron and proton transfer reactions during the O→E transition in bovine cytochrome c oxidase.Current advances in research of cytochrome c oxidase.Role of water and protein dynamics in proton pumping by respiratory complex I.B3LYP study on reduction mechanisms from O2 to H2O at the catalytic sites of fully reduced and mixed-valence bovine cytochrome c oxidases.Structural Changes and Proton Transfer in Cytochrome c Oxidase.Water exit pathways and proton pumping mechanism in B-type cytochrome c oxidase from molecular dynamics simulations.Proton transfer in the K-channel analog of B-type Cytochrome c oxidase from Thermus thermophilusRETRACTED: Protonation State-Dependent Communication in Cytochrome c Oxidase.Similarity of cytochrome c oxidases in different organisms.Molecular dynamics simulation of water in cytochrome c oxidase reveals two water exit pathways and the mechanism of transport.Elevated proton leak of the intermediate OH in cytochrome c oxidase.A structural and functional perspective on the evolution of the heme-copper oxidases.Understanding the essential proton-pumping kinetic gates and decoupling mutations in cytochrome c oxidase.
P2860
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P2860
Glutamic acid 242 is a valve in the proton pump of cytochrome c oxidase.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Glutamic acid 242 is a valve in the proton pump of cytochrome c oxidase.
@ast
Glutamic acid 242 is a valve in the proton pump of cytochrome c oxidase.
@en
type
label
Glutamic acid 242 is a valve in the proton pump of cytochrome c oxidase.
@ast
Glutamic acid 242 is a valve in the proton pump of cytochrome c oxidase.
@en
prefLabel
Glutamic acid 242 is a valve in the proton pump of cytochrome c oxidase.
@ast
Glutamic acid 242 is a valve in the proton pump of cytochrome c oxidase.
@en
P2860
P356
P1476
Glutamic acid 242 is a valve in the proton pump of cytochrome c oxidase
@en
P2093
Michael I Verkhovsky
Mårten Wikström
P2860
P304
P356
10.1073/PNAS.0800770105
P407
P577
2008-04-22T00:00:00Z