Nf2/Merlin: a coordinator of receptor signalling and intercellular contact
about
Neurofibromatosis type 2 protein, NF2: an uncoventional cell cycle regulator.New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomasModel membranes to shed light on the biochemical and physical properties of ezrin/radixin/moesinPar6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers.Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressorActin up for Hippo.Hippo/YAP pathway for targeted therapyMaternally expressed gene 3, an imprinted noncoding RNA gene, is associated with meningioma pathogenesis and progressionMerlin, a "magic" linker between extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survivalTumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivatorsQuantitative assessment of whole-body tumor burden in adult patients with neurofibromatosisChildhood neurofibromatosis type 2 (NF2) and related disorders: from bench to bedside and biologically targeted therapies.Genetic predisposition to peripheral nerve neoplasia: diagnostic criteria and pathogenesis of neurofibromatoses, Carney complex, and related syndromesPreclinical validation of AR42, a novel histone deacetylase inhibitor, as treatment for vestibular schwannomas.AR42, a novel histone deacetylase inhibitor, as a potential therapy for vestibular schwannomas and meningiomas.Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma.Merlin expression in pediatric anaplastic ependymomas real time PCR study.NHERF1/EBP50 is a new marker in colorectal cancer.The mTOR signaling pathway as a treatment target for intracranial neoplasmsCD43 promotes cells transformation by preventing merlin-mediated contact inhibition of growthDNA microarray analysis identifies CKS2 and LEPR as potential markers of meningioma recurrence.NF2 blocks Snail-mediated p53 suppression in mesothelioma.NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.Origins of magic: review of genetic and epigenetic effectsPersonalized comprehensive molecular profiling of high risk osteosarcoma: Implications and limitations for precision medicineOut, in and back again: PtdIns(4,5)P(2) regulates cadherin trafficking in epithelial morphogenesis.Cell density-dependent inhibition of epidermal growth factor receptor signaling by p38alpha mitogen-activated protein kinase via Sprouty2 downregulationErbin and the NF2 tumor suppressor Merlin cooperatively regulate cell-type-specific activation of PAK2 by TGF-beta.The aryl hydrocarbon receptor (AhR) in the regulation of cell-cell contact and tumor growth.Dermatological manifestations of inherited cancer syndromes in children.Mst1/2 signalling to Yap: gatekeeper for liver size and tumour development.Regulation of leg size and shape: involvement of the Dachsous-fat signaling pathway.Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation.Rac1 controls Schwann cell myelination through cAMP and NF2/merlin.Activation of multiple growth factor signalling pathways is frequent in meningiomas.Tumor suppressor function of ezrin-radixin-moesin-binding phosphoprotein-50 through β-catenin/E-cadherin pathway in human hepatocellular cancer.Overexpression of ezrin inactivates NF2 tumor suppressor in glioblastoma.Pak1 control of E-cadherin endocytosis regulates salivary gland lumen size and shape.Merlin in organ size control and tumorigenesis: Hippo versus EGFR?Neurofibromatosis: types 1 and 2.
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Nf2/Merlin: a coordinator of receptor signalling and intercellular contact
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Nf2/Merlin: a coordinator of receptor signalling and intercellular contact
@ast
Nf2/Merlin: a coordinator of receptor signalling and intercellular contact
@en
type
label
Nf2/Merlin: a coordinator of receptor signalling and intercellular contact
@ast
Nf2/Merlin: a coordinator of receptor signalling and intercellular contact
@en
prefLabel
Nf2/Merlin: a coordinator of receptor signalling and intercellular contact
@ast
Nf2/Merlin: a coordinator of receptor signalling and intercellular contact
@en
P2860
P921
P356
P1476
Nf2/Merlin: a coordinator of receptor signalling and intercellular contact
@en
P2093
A I McClatchey
P2860
P2888
P304
P356
10.1038/SJ.BJC.6604002
P407
P577
2007-10-30T00:00:00Z
2008-01-29T00:00:00Z
P5875
P6179
1031304160