Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection - Wikidata - awgldk - TriplyDB

Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection

Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection

http://www.wikidata.org/entity/Q36619693

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Mucosal-associated invariant T cells from induced pluripotent stem cells: A novel approach for modeling human diseases Mucosal-associated invariant T cells in autoimmunity, immune-mediated diseases and airways disease Mucosal-Associated Invariant T Cells in Multiple Sclerosis: The Jury is Still Out Regulation of Lipid Specific and Vitamin Specific Non-MHC Restricted T Cells by Antigen Presenting Cells and Their Therapeutic Potentials Early innate responses to pathogens: pattern recognition by unconventional human T-cells MR1-Restricted Mucosal-Associated Invariant T Cells and Their Activation during Infectious Diseases T cell recognition of non-peptidic antigens in infectious diseases Universal immunity to influenza must outwit immune evasion MAIT cells are activated during human viral infections Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells Recognition of vitamin B metabolites by mucosal-associated invariant T cells Complex adaptive immunity to enteric fevers in humans: lessons learned and the path forward MAIT cells: new guardians of the liver Innate-like lymphocytes in intestinal infections Check MAIT.Multiple layers of heterogeneity and subset diversity in human MAIT cell responses to distinct microorganisms and to innate cytokines.Circulating mucosal associated invariant T cells are activated in Vibrio cholerae O1 infection and associated with lipopolysaccharide antibody responses.Mucosal-associated invariant T-cells: new players in anti-bacterial immunity Reduced mucosal associated invariant T-cells are associated with increased disease severity and Pseudomonas aeruginosa infection in cystic fibrosis.Innate mucosal-associated invariant T (MAIT) cells are activated in inflammatory bowel diseases.CD161+ MAIT cells are severely reduced in peripheral blood and lymph nodes of HIV-infected individuals independently of disease progression Persistent immune activation in chronic HIV infection: do any interventions work?MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets.Persistent changes in circulating and intestinal γδ T cell subsets, invariant natural killer T cells and mucosal-associated invariant T cells in children and adults with coeliac disease.Altered CD161 bright CD8+ mucosal associated invariant T (MAIT)-like cell dynamics and increased differentiation states among juvenile type 1 diabetics.Low levels of peripheral CD161++CD8+ mucosal associated invariant T (MAIT) cells are found in HIV and HIV/TB co-infection.Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients.Involvement of a C-terminal motif in the interference of primate lentiviral Vpu proteins with CD1d-mediated antigen presentation.Attrition of TCR Vα7.2+ CD161++ MAIT cells in HIV-tuberculosis co-infection is associated with elevated levels of PD-1 expression.Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection.Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites.Mucosal-associated invariant T cell-rich congenic mouse strain allows functional evaluation.MAIT cells are activated and accumulated in the inflamed mucosa of ulcerative colitis.Mucosal-Associated Invariant T (MAIT) Cells Are Impaired in Th17 Associated Primary and Secondary Immunodeficiencies.Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy Activation, Impaired Tumor Necrosis Factor-α Production, and Deficiency of Circulating Mucosal-Associated Invariant T Cells in Patients with Scrub Typhus.HIV-Infected Children Have Lower Frequencies of CD8+ Mucosal-Associated Invariant T (MAIT) Cells that Correlate with Innate, Th17 and Th22 Cell Subsets.Molecular Analyses Define Vα7.2-Jα33+ MAIT Cell Depletion in HIV Infection: A Case-Control Study.Silymarin suppresses basal and stimulus-induced activation, exhaustion, differentiation, and inflammatory markers in primary human immune cells MAIT cells are reduced in frequency and functionally impaired in human T lymphotropic virus type 1 infection: Potential clinical implications.

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P2860

Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection

http://www.wikidata.org/entity/Q36619693

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2012年论文

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Activation, exhaustion, and pe ...... ion in chronic HIV-1 infection

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Anupama Ganesh

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Jan Andersson

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Jeffrey N Martin

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Ma Somsouk

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Máire F Quigley

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Peter W Hunt

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P2860

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

The non-conventional MHC class I MR1 molecule controls infection by Klebsiella pneumoniae in mice

Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor

MR1 presents microbial vitamin B metabolites to MAIT cells

Cutting edge: lectin-like transcript 1 is a ligand for the CD161 receptor

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

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Johan K Sandberg

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Anders Sönnerborg

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