Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis.
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Displayed correlation between gene expression profiles and submicroscopic alterations in response to cetuximab, gefitinib and EGF in human colon cancer cell lines.Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer.The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies.Inhibition of apoptosis by amphiregulin via an insulin-like growth factor-1 receptor-dependent pathway in non-small cell lung cancer cell lines.Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells.Integrin alpha5/beta1 mediates fibronectin-dependent epithelial cell proliferation through epidermal growth factor receptor activationIdentification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer.Rational identification of an optimal antibody mixture for targeting the epidermal growth factor receptor.Multiple personalities of neuregulin gene family members.Ret heterozygous mice have enhanced intestinal adaptation after massive small bowel resection.Conditional deletion of beta1 integrins in the intestinal epithelium causes a loss of Hedgehog expression, intestinal hyperplasia, and early postnatal lethality.Amphiregulin enhances intercellular adhesion molecule-1 expression and promotes tumor metastasis in human osteosarcomaMyofibroblast keratinocyte growth factor reduces tight junctional integrity and increases claudin-2 levels in polarized Caco-2 cells.Effect of blockade of the EGF system on wound healing in patients vaccinated with CIMAvax® EGF.The neoadjuvant therapy of colorectal hepatic metastases and the role of biologic sensitizing and resistance factors.In vitro combined treatment with cetuximab and trastuzumab inhibits growth of colon cancer cells.Nuclear translocation of pro-amphiregulin induces chemoresistance in gastric cancer.Identification of a novel mono-leucine basolateral sorting motif within the cytoplasmic domain of amphiregulin.Epidermal growth factor and/or growth hormone induce differential, side-specific signal transduction protein phosphorylation in enterocytes.Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation.DNA microarray analysis of vitamin D-induced gene expression in a human colon carcinoma cell line.Epidermal growth factor receptor mutation type III transfected into a small cell lung cancer cell line is predominantly localized at the cell surface and enhances the malignant phenotype.Medium-chain fatty acids stimulate interleukin-8 production in Caco-2 cells with different mechanisms from long-chain fatty acids.The proamphiregulin cytoplasmic domain is required for basolateral sorting, but is not essential for constitutive or stimulus-induced processing in polarized Madin-Darby canine kidney cells.Oncogenic KRAS desensitizes colorectal tumor cells to epidermal growth factor receptor inhibition and activation.Therapeutic efficacy of SYM004, a mixture of two anti-EGFR antibodies in human colorectal cancer with acquired resistance to cetuximab and MET activation.The invasive phenotype of Shigella flexneri directs a distinct gene expression pattern in the human intestinal epithelial cell line Caco-2.
P2860
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P2860
Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Amphiregulin acts as an autocr ...... tive EGF receptor mitogenesis.
@ast
Amphiregulin acts as an autocr ...... tive EGF receptor mitogenesis.
@en
type
label
Amphiregulin acts as an autocr ...... tive EGF receptor mitogenesis.
@ast
Amphiregulin acts as an autocr ...... tive EGF receptor mitogenesis.
@en
prefLabel
Amphiregulin acts as an autocr ...... tive EGF receptor mitogenesis.
@ast
Amphiregulin acts as an autocr ...... tive EGF receptor mitogenesis.
@en
P2093
P2860
P356
P1476
Amphiregulin acts as an autocr ...... ctive EGF receptor mitogenesis
@en
P2093
C J Hawkey
H S Poulsen
L Damstrup
P J Dempsey
R J Coffey
S K Kuwada
P2860
P2888
P304
P356
10.1038/SJ.BJC.6690456
P407
P50
P577
1999-06-01T00:00:00Z