Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation - Wikidata - awgldk - TriplyDB

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

http://www.wikidata.org/entity/Q36621970

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Human induced pluripotent stem cells for monogenic disease modelling and therapy Organoid Models of Human Gastrointestinal Development and Disease Liver-Regenerative Transplantation: Regrow and Reset Drug Discovery via Human-Derived Stem Cell Organoids Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modelling.Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury Genome engineering of stem cell organoids for disease modeling.Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells.Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion.Notch Signaling Coordinates Progenitor Cell-Mediated Biliary Regeneration Following Partial Hepatectomy.Role of β-catenin in development of bile ducts.Cell sources for in vitro human liver cell culture models.Development of a rapid screen for the endodermal differentiation potential of human pluripotent stem cell lines Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells.Kidney Organoids: A Translational Journey.Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids.Current strategies to generate mature human induced pluripotent stem cells derived cholangiocytes and future applications.Modeling Cystic Fibrosis Using Pluripotent Stem Cell-Derived Human Pancreatic Ductal Epithelial Cells Patient-derived induced pluripotent stem cells in cancer research and precision oncology.Three-dimensional pancreas organogenesis models.The role of hepatocyte nuclear factor 1β in disease and development.Expression kinetics of hepatic progenitor markers in cellular models of human liver development recapitulating hepatocyte and biliary cell fate commitment.Efficient and Controlled Generation of 2D and 3D Bile Duct Tissue from Human Pluripotent Stem Cell-Derived Spheroids.Modeling of Autism Using Organoid Technology.Induced pluripotent stem cell technology: a decade of progress.Regenerative Medicine and the Biliary Tree.Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis.Stem cell-derived organoids to model gastrointestinal facets of cystic fibrosis.Human hepatic organoids for the analysis of human genetic diseases.Alagille syndrome: Genetics and Functional Models.The long and winding road: stem cells for cystic fibrosis.Development and characterization of cholangioids from normal and diseased human cholangiocytes as an in vitro model to study primary sclerosing cholangitis.Bioengineering: Bile ducts regenerated.The Human Cell Atlas: Technical approaches and challenges.Rapid Screening of the Endodermal Differentiation Potential of Human Pluripotent Stem Cells.A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells.Modeling Inborn Errors of Hepatic Metabolism Using Induced Pluripotent Stem Cells.A single-cell transcriptomic analysis reveals precise pathways and regulatory mechanisms underlying hepatoblast differentiation.Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond.Direct Conversion of Mouse Fibroblasts into Cholangiocyte Progenitor Cells.

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Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

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Cholangiocytes derived from hu ...... e modeling and drug validation

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Cholangiocytes derived from hu ...... e modeling and drug validation

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Arthur Kaser

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Elisabeth Schrumpf

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Espen Melum

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Filipa A C Soares

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Fotios Sampaziotis

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Graeme J Alexander

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Miguel Cardoso de Brito

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Susan Davies

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P2860

Alagille syndrome: pathogenesis, diagnosis and management

Cystic fibrosis

Pathophysiology of cystic fibrosis and drugs used in associated digestive tract diseases

Polycystic liver disease: a clinical review

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

Cystic fibrosis

Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors

Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9

Cystic fibrosis related liver disease--another black box in hepatology.

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10.1038/NBT.3275

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8

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33

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Alessandro Bertero

Kourosh Saeb-Parsy

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Nicholas Hannan

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2015-07-13T00:00:00Z

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26167629

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Human Induced Pluripotent Stem Cells

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4768345

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