PBX3 is an important cofactor of HOXA9 in leukemogenesis. - Wikidata - awgldk - TriplyDB

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

http://www.wikidata.org/entity/Q36628305

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Role of HOXA9 in leukemia: dysregulation, cofactors and essential targets Targeting HOX transcription factors in prostate cancer miR-155 expression and correlation with clinical outcome in pediatric AML: A report from Children's Oncology Group.CBFB-MYH11 hypomethylation signature and PBX3 differential methylation revealed by targeted bisulfite sequencing in patients with acute myeloid leukemia.A pan-cancer modular regulatory network analysis to identify common and cancer-specific network components.The molecular mechanics of mixed lineage leukemia.PBX3 promotes migration and invasion of colorectal cancer cells via activation of MAPK/ERK signaling pathway.Two decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia.Fusion of the genes EWSR1 and PBX3 in retroperitoneal leiomyoma with t(9;22)(q33;q12).Tetraspanin 3 Is Required for the Development and Propagation of Acute Myelogenous Leukemia Identification of MLL-fusion/MYC⊣miR-26⊣TET1 signaling circuit in MLL-rearranged leukemia.PBX3 and MEIS1 Cooperate in Hematopoietic Cells to Drive Acute Myeloid Leukemias Characterized by a Core Transcriptome of the MLL-Rearranged Disease miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia.TET1 plays an essential oncogenic role in MLL-rearranged leukemia The fusion partner specifies the oncogenic potential of NUP98 fusion proteins MicroRNA-33a-3p suppresses cell migration and invasion by directly targeting PBX3 in human hepatocellular carcinoma.MicroRNA-497 suppresses cell proliferation and induces apoptosis through targeting PBX3 in human multiple myeloma.Downregulation of homeobox gene Barx2 increases gastric cancer proliferation and metastasis and predicts poor patient outcomes Hox gene dysregulation in acute myeloid leukemia.PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells.Deregulation of the HOXA9/MEIS1 axis in acute leukemia.PBX3 is overexpressed in gastric cancer and regulates cell proliferation.Targeting HOX/PBX dimers in cancer.The cohesin subunit Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9.The miR-17∼92 cluster contributes to MLL leukemia through the repression of MEIS1 competitor PKNOX1 The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia.RNA and protein expression of herpesvirus entry mediator (HVEM) is associated with molecular markers, immunity-related pathways and relapse-free survival of patients with AML.Upregulation of Flt3 is a passive event in Hoxa9/Meis1-induced acute myeloid leukemia in mice.Pbx3 and Meis1 cooperate through multiple mechanisms to support Hox-induced murine leukemia.MiR-320 inhibits the growth of glioma cells through downregulating PBX3.Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia.PBX3 promotes gastric cancer invasion and metastasis by inducing epithelial-mesenchymal transition.Dangerous liaisons: cooperation between Pbx3, Meis1 and Hoxa9 in leukemia.Screening and identification of critical transcription factors involved in the protection of cardiomyocytes against hydrogen peroxide-induced damage by Yixin-shu.HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy.Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells.High level of homeobox A9 and PBX homeobox 3 expression in gastric cancer correlates with poor prognosis.PBX3 is associated with proliferation and poor prognosis in patients with cervical cancer.High expression of FLT3 is a risk factor in leukemia.

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P2860

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

http://www.wikidata.org/entity/Q36628305

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

@zh-hk

2012年論文

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2012年論文

@zh-tw

2012年论文

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2012年论文

@zh

2012年论文

@zh-cn

name

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

@ast

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

@en

type

label

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

@ast

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

@en

prefLabel

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

@ast

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

@en

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BLOOD-2012-07-442004

P1433

P1476

PBX3 is an important cofactor of HOXA9 in leukemogenesis.

@en

P2093

Abdel G Elkahloun

http://www.w3.org/2001/XMLSchema#string

Chong-Zhi Wang

http://www.w3.org/2001/XMLSchema#string

Chun-Su Yuan

http://www.w3.org/2001/XMLSchema#string

Chunjiang He

http://www.w3.org/2001/XMLSchema#string

Gia-Ming Hong

http://www.w3.org/2001/XMLSchema#string

Hao Huang

http://www.w3.org/2001/XMLSchema#string

Haomin Ren

http://www.w3.org/2001/XMLSchema#string

Janet D Rowley

http://www.w3.org/2001/XMLSchema#string

Jianjun Chen

http://www.w3.org/2001/XMLSchema#string

Lars Bullinger

http://www.w3.org/2001/XMLSchema#string

P2860

PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1

HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells

Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization

Identification and characterization of Hoxa9 binding sites in hematopoietic cells

Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia

Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated gene- and microRNA-expression signatures: a Cancer and Leukemia Group B study.

A microRNA polycistron as a potential human oncogene

Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins

Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9.

Targeting HOX and PBX transcription factors in ovarian cancer.

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10.1182/BLOOD-2012-07-442004

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8

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121

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Konstanze Döhner

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2012-12-20T00:00:00Z

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233977632

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23264595

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3578957

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