On the potential of thioredoxin reductase inhibitors for cancer therapy.
about
Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancerCisplatin and oxaliplatin toxicity: importance of cochlear kinetics as a determinant for ototoxicityMitochondrial Redox Signaling and Tumor ProgressionThioredoxin Reductase from Thermoplasma acidophilum : A New Twist on Redox Regulation † , ‡Crystal structure and catalysis of the selenoprotein thioredoxin reductase 1Crystal structure of the human thioredoxin reductase-thioredoxin complexGlutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agentsThioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingParadoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health ImplicationsThe effects of di(2-ethylhexyl)phthalate on rat liver in relation to selenium statusIn vitro and in vivo activity of an organic tellurium compound on Leishmania (Leishmania) chagasiThe Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry InhibitionChemical Reactivity Window Determines Prodrug Efficiency toward Glutathione Transferase Overexpressing Cancer CellsIndolin-2-one compounds targeting thioredoxin reductase as potential anticancer drug leadsTargeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide.Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replicationCell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cellsPenultimate selenocysteine residue replaced by cysteine in thioredoxin reductase from selenium-deficient rat liver.Cisplatin and oxaliplatin are toxic to cochlear outer hair cells and both target thioredoxin reductase in organ of Corti culturesThioredoxin reductase-1 mediates curcumin-induced radiosensitization of squamous carcinoma cellsThe selenium-independent inherent pro-oxidant NADPH oxidase activity of mammalian thioredoxin reductase and its selenium-dependent direct peroxidase activities.Antiproliferative effect of gold(I) compound auranofin through inhibition of STAT3 and telomerase activity in MDA-MB 231 human breast cancer cells.Annatto constituent cis-bixin has selective antimyeloma effects mediated by oxidative stress and associated with inhibition of thioredoxin and thioredoxin reductaseGrowth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.Polymorphisms in thioredoxin reductase and selenoprotein K genes and selenium status modulate risk of prostate cancer.Novel insights into the synergistic interaction of a thioredoxin reductase inhibitor and TRAIL: the activation of the ASK1-ERK-Sp1 pathway.Alteration of thioredoxin reductase 1 levels in elucidating cancer etiology.Susceptibility of the antioxidant selenoenyzmes thioredoxin reductase and glutathione peroxidase to alkylation-mediated inhibition by anticancer acylfulvenesAntitumor indolequinones induced apoptosis in human pancreatic cancer cells via inhibition of thioredoxin reductase and activation of redox signaling.Redox effects and cytotoxic profiles of MJ25 and auranofin towards malignant melanoma cells.Thioredoxin reductase is inhibited by the carbamoylating activity of the anticancer sulfonylhydrazine drug laromustine.Thioredoxin reductase 1 deficiency enhances selenite toxicity in cancer cells via a thioredoxin-independent mechanismThioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis.Ruthenium(II) Complexes with 2-Phenylimidazo[4,5-f][1,10]phenanthroline Derivatives that Strongly Combat Cisplatin-Resistant Tumor CellsB5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy.Arsenic trioxide and auranofin inhibit selenoprotein synthesis: implications for chemotherapy for acute promyelocytic leukaemia.Redox activation of Fe(III)-thiosemicarbazones and Fe(III)-bleomycin by thioredoxin reductase: specificity of enzymatic redox centers and analysis of reactive species formation by ESR spin trappingNew trends for metal complexes with anticancer activityEF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells.Thiol chemistry in peroxidase catalysis and redox signaling.
P2860
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P2860
On the potential of thioredoxin reductase inhibitors for cancer therapy.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
On the potential of thioredoxin reductase inhibitors for cancer therapy.
@ast
On the potential of thioredoxin reductase inhibitors for cancer therapy.
@en
type
label
On the potential of thioredoxin reductase inhibitors for cancer therapy.
@ast
On the potential of thioredoxin reductase inhibitors for cancer therapy.
@en
prefLabel
On the potential of thioredoxin reductase inhibitors for cancer therapy.
@ast
On the potential of thioredoxin reductase inhibitors for cancer therapy.
@en
P1476
On the potential of thioredoxin reductase inhibitors for cancer therapy.
@en
P2093
Katja Becker
Sabine Urig
P304
P356
10.1016/J.SEMCANCER.2006.09.004
P577
2006-09-26T00:00:00Z