Aurora A regulates the activity of HURP by controlling the accessibility of its microtubule-binding domain.
about
Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora ANon-centrosomal TPX2-Dependent Regulation of the Aurora A Kinase: Functional Implications for Healthy and Pathological Cell DivisionTime-lapse imaging of neuroblastoma cells to determine cell fate upon gene knockdownAurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubulesMolecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2Inhibition of apoptosis by oncogenic hepatitis B virus X protein: Implications for the treatment of hepatocellular carcinomaAllosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2Microtubule-dependent regulation of mitotic protein degradation.Global gene expression profiling of human pleural mesotheliomas: identification of matrix metalloproteinase 14 (MMP-14) as potential tumour targetBinding partner switching on microtubules and aurora-B in the mitosis to cytokinesis transition.Abnormal kinetochore-generated pulling forces from expressing a N-terminally modified Hec1.Aurora A contributes to p150(glued) phosphorylation and function during mitosisFinding the middle ground: how kinetochores power chromosome congression.Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.HURP expression-assisted risk scores identify prognosis distinguishable subgroups in early stage liver cancer.Hepatoma upregulated protein expression is involved in the pathogenesis of human breast carcinogenesis.Tripolin A, a novel small-molecule inhibitor of aurora A kinase, reveals new regulation of HURP's distribution on microtubules.Hurp deficiency in mice leads to female infertility caused by an implantation defect.cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomesDefining NOTCH3 target genes in ovarian cancer.The nucleoporin ALADIN regulates Aurora A localization to ensure robust mitotic spindle formation.Aurora A kinase (AURKA) in normal and pathological cell division.Mitotic Stress and Chromosomal Instability in Cancer: The Case for TPX2.Hepatoma up-regulated protein is required for chromatin-induced microtubule assembly independently of TPX2mars and tousled-like kinase act in parallel to ensure chromosome fidelity in Drosophila.Cdk1-cyclin B1-mediated phosphorylation of tumor-associated microtubule-associated protein/cytoskeleton-associated protein 2 in mitosis.AURKA, DLGAP5, TPX2, KIF11 and CKAP5: Five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patients.Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins.Learning about cancer from frogs: analysis of mitotic spindles in Xenopus egg extracts.Substrate-specific regulation of ubiquitination by the anaphase-promoting complex.Regulated degradation of spindle assembly factors by the anaphase-promoting complex.FAM29A, a target of Plk1 regulation, controls the partitioning of NEDD1 between the mitotic spindle and the centrosomes.Evaluation of urinary HURP mRNA as a marker for detection of bladder cancer: relation to bilharziasis.The multifaceted allosteric regulation of Aurora kinase A.
P2860
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P2860
Aurora A regulates the activity of HURP by controlling the accessibility of its microtubule-binding domain.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Aurora A regulates the activit ...... ts microtubule-binding domain.
@ast
Aurora A regulates the activit ...... ts microtubule-binding domain.
@en
type
label
Aurora A regulates the activit ...... ts microtubule-binding domain.
@ast
Aurora A regulates the activit ...... ts microtubule-binding domain.
@en
prefLabel
Aurora A regulates the activit ...... ts microtubule-binding domain.
@ast
Aurora A regulates the activit ...... ts microtubule-binding domain.
@en
P2093
P2860
P356
P1476
Aurora A regulates the activit ...... ts microtubule-binding domain.
@en
P2093
Chang-Young Jang
Guowei Fang
Robert Lerrigo
P2860
P304
P356
10.1091/MBC.E07-10-1088
P577
2008-03-05T00:00:00Z