Reduction in levels of the cyclin-dependent kinase inhibitor p27(kip-1) coupled with transforming growth factor beta neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells.
about
Hematopoietic stem cell: self-renewal versus differentiationThe role of Smad signaling in hematopoiesis.Fluorophore-conjugated iron oxide nanoparticle labeling and analysis of engrafting human hematopoietic stem cells.Transient inhibition of transforming growth factor-beta1 in human diabetic CD34+ cells enhances vascular reparative functions.In vivo biosafety model to assess the risk of adverse events from retroviral and lentiviral vectors.Label-retaining, quiescent globose basal cells are found in the olfactory epithelium.Gene therapy to protect haematopoietic cells from cytotoxic cancer drugs.Stable transduction of quiescent CD34(+)CD38(-) human hematopoietic cells by HIV-1-based lentiviral vectorsTransforming growth factor-beta signaling in normal and malignant hematopoiesis.Molecular mechanism of transforming growth factor beta-mediated cell-cycle modulation in primary human CD34(+) progenitors.Transient silencing of PTEN in human CD34(+) cells enhances their proliferative potential and ability to engraft immunodeficient miceCytokine and integrin stimulation synergize to promote higher levels of GATA-2, c-myb, and CD34 protein in primary human hematopoietic progenitors from bone marrow.Hematopoietic stem cells: transcriptional regulation, ex vivo expansion and clinical application.Cell cycle inhibitors in normal and tumor stem cells.Regulation of hematopoietic stem cell growth.Clinical strategies for expansion of haematopoietic stem cells.Hematopoiesis and thymic apoptosis are not affected by the loss of Cdk2.Changes in the proliferative activity of human hematopoietic stem cells in NOD/SCID mice and enhancement of their transplantability after in vivo treatment with cell cycle inhibitorsThe CDK inhibitors: potential targets for therapeutic stem cell manipulations?Directing mesenchymal stem cells to bone to augment bone formation and increase bone massThe TEL-AML1 leukemia fusion gene dysregulates the TGF-beta pathway in early B lineage progenitor cells.Albumin-expressing hepatocyte-like cells develop in the livers of immune-deficient mice that received transplants of highly purified human hematopoietic stem cells.Contribution of human hematopoietic stem cells to liver repair.Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation.The role of Smad signaling in hematopoiesis and translational hematology.Stem cell bioengineering strategies to widen the therapeutic applications of haematopoietic stem/progenitor cells from umbilical cord blood.Deconstructing the Complexity of TGFβ Signaling in Hematopoietic Stem Cells: Quiescence and Beyond.Proteasome activity restricts lentiviral gene transfer into hematopoietic stem cells and is down-regulated by cytokines that enhance transduction.Azacytidine (Vidaza(R)) in the treatment of myelodysplastic syndromes.Mesenchymal stem cells for trinucleotide repeat disordersIn vivo distribution of human adipose-derived mesenchymal stem cells in novel xenotransplantation models.The high proliferative potential-quiescent (HPP-Q) cell assay allows an optimized evaluation of gene transfer efficiency into primitive hematopoietic stem/progenitor cells.Silencing p21(Waf1/Cip1/Sdi1) expression increases gene transduction efficiency in primitive human hematopoietic cells.
P2860
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P2860
Reduction in levels of the cyclin-dependent kinase inhibitor p27(kip-1) coupled with transforming growth factor beta neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Reduction in levels of the cyc ...... ive human hematopoietic cells.
@ast
Reduction in levels of the cyc ...... ive human hematopoietic cells.
@en
type
label
Reduction in levels of the cyc ...... ive human hematopoietic cells.
@ast
Reduction in levels of the cyc ...... ive human hematopoietic cells.
@en
prefLabel
Reduction in levels of the cyc ...... ive human hematopoietic cells.
@ast
Reduction in levels of the cyc ...... ive human hematopoietic cells.
@en
P2093
P2860
P356
P1476
Reduction in levels of the cyc ...... ive human hematopoietic cells.
@en
P2093
P2860
P304
13006-13011
P356
10.1073/PNAS.95.22.13006
P407
P577
1998-10-01T00:00:00Z