Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation. - Wikidata - awgldk - TriplyDB

Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation.

Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation.

http://www.wikidata.org/entity/Q36635311

about

Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies Telomere and Telomerase Therapeutics in Cancer Human Specific Regulation of the Telomerase Reverse Transcriptase Gene The NF-κB Pathway and Cancer Stem Cells Reactivation of telomerase in cancer IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance.The interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets The ETS family of oncogenic transcription factors in solid tumours.Association of telomerase reverse transcriptase promoter mutations with clinicopathological features and prognosis of thyroid cancer: a meta-analysis.Telomerase reactivation in cancers: Mechanisms that govern transcriptional activation of the wild-type vs. mutant TERT promoters Phosphoprotein network analysis of white adipose tissues unveils deregulated pathways in response to high-fat diet.Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression Activation of mutant TERT promoter by RAS-ERK signaling is a key step in malignant progression of BRAF-mutant human melanomas.Inhibition of NUCKS Facilitates Corneal Recovery Following Alkali Burn Association of TERT promoter mutations with telomerase expression in melanoma.Transcriptional Regulation of Telomerase Reverse Transcriptase (TERT) by MYC.Gene networks activated by specific patterns of action potentials in dorsal root ganglia neurons.Current Insights to Regulation and Role of Telomerase in Human Diseases.Treating Cancer by Targeting Telomeres and Telomerase.Understanding TERT Promoter Mutations: A Common Path to Immortality.An interaction proteomics survey of transcription factor binding at recurrent TERT promoter mutations.Altered TERT promoter and other genomic regulatory elements: occurrence and impact.Contemporary and potential future molecular diagnosis of melanoma.Wanted DEAD/H or Alive: Helicases Winding Up in Cancers.Repression of telomerase gene promoter requires human-specific genomic context and is mediated by multiple HDAC1-containing corepressor complexes.TERT promoter mutations in melanoma survival.Mass spectrometry-based assay for the molecular diagnosis of glioma: concomitant detection of chromosome 1p/19q codeletion, and IDH1, IDH2, and TERT mutation status.Ikk2 regulates cytokinesis during vertebrate development.Thyroid transcription factor FOXE1 interacts with ETS factor ELK1 to co-regulate TERT.TERT promoter mutations in melanoma render TERT expression dependent on MAPK pathway activation.Functional dissection of breast cancer risk-associated TERT promoter variants.TERT Promoter Mutations Enhance Telomerase Activation by Long-Range Chromatin Interactions.NFκB drives TERT promoter reactivation in cancer.ETS1, nucleolar and non-nucleolar TERT expression in nevus to melanoma progression.Prognostic impact and concordance of TERT promoter mutation and protein expression in matched primary and metastatic cutaneous melanoma.Telomerase reverse transcriptase (TERT) - enhancer of zeste homolog 2 (EZH2) network regulates lipid metabolism and DNA damage responses in glioblastoma.Stabilization of NF-κB-Inducing Kinase Suppresses MLL-AF9-Induced Acute Myeloid Leukemia.Insights about genome function from spatial organization of the genome.Multispectral optoacoustic and MRI coregistration for molecular imaging of orthotopic model of human glioblastoma.

P2860

Q26739925-14AD4257-69D2-45DF-B8D2-CC3B404F7455 Q26744271-94932E03-67A2-4C74-B400-850D15A2B6F9 Q26744808-BD762570-415F-4D57-9FA3-A165436BFFAA Q26745549-18F5E1EF-FA02-445F-9F41-808F6F2904C3 Q26750605-5A2255AF-DADE-43D8-883A-FA7100FBACF4 Q26769014-8838F71C-33C8-4C3B-85DE-C1120512D1AD Q33276239-6F0A69F9-2DF6-457D-B713-681F21765990 Q33566723-AC29DCB1-18AD-4E95-B6DE-D8A102CA3FA3 Q34555986-99A3E98A-FCE1-45B6-8346-3CE5F83F6583 Q36221232-FED8A5B0-00BB-4CBC-8979-179749557B84 Q36857933-A5000F84-D20B-4911-956D-3FC3D3044603 Q36903098-27640B83-B359-46BA-B046-AF9B0A27861B Q37395716-D448873E-2440-44F5-BF1C-418865B68AE5 Q37514988-B5F31694-7659-4396-A864-0085A07E89E8 Q37595322-5B40F624-7567-458B-BB0B-D73774618479 Q37596033-DF8F231B-C080-4C63-A55B-152553BFFBED Q37607116-CD530D77-6ADE-404F-A335-4A5C3D531224 Q37678884-9BD2A87B-2B47-4891-8CD0-C5CE269B2F21 Q37741228-3F3D3624-FB64-4886-85C6-57907F8F35E7 Q38288984-D61283F6-FDF0-4CB1-9A2F-1972F61F3BA7 Q38760235-ADF885CA-42AA-4248-B9F2-E8D721EE2BD4 Q38820649-6F1CDE35-8415-4C07-8612-C26B7E8C7925 Q38838144-91DD8B6A-1C90-4392-9EDA-C3F6365748D9 Q38847989-C8299F8D-F75F-4E44-B653-2C4B09F0D61F Q38998990-28A65B95-54D8-45DE-BDA7-D9AD5BA30762 Q39111698-A82C527E-DE0F-4484-8D6E-D0BC5AB7504B Q39998496-1F9D9A2F-5983-449C-A9FC-E4BE2C84612D Q41342863-AEBBFC8B-F342-4C5D-947F-CAE282468825 Q41387328-87610B23-7C72-4801-B7C2-B6EA859A4802 Q42016940-3E20772D-662D-4F1D-80CE-407AB2FE6C8B Q42324664-2438C42E-5DBC-479D-9DEF-0584672A4B91 Q42366538-33692521-3BA7-4B5A-AE76-F19582AC9B4E Q42748231-C335BC87-8821-477D-A317-7376FE4BD88F Q42910096-02075BD1-E195-46DB-9D20-707CCC3C8C67 Q47224965-3E3D5D3A-8C58-4B6E-A18D-E09066E4F1F7 Q47418685-F0CBBCFF-D821-477E-853D-5E3664BAFB03 Q47916801-72114BE2-96E9-4730-8B16-AC8C8354E2E1 Q49216080-700A0296-C77E-40BC-9F3E-A589EA6F3290 Q49843050-EC15F757-7172-4F7C-B6FF-05CADB8960BD Q52139277-B5542B16-583B-4CAF-9173-BB99641ED3FC

P2860

Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation.

http://www.wikidata.org/entity/Q36635311

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Non-canonical NF-κB signalling ...... tant TERT promoter activation.

@ast

Non-canonical NF-κB signalling ...... tant TERT promoter activation.

@en

type

label

Non-canonical NF-κB signalling ...... tant TERT promoter activation.

@ast

Non-canonical NF-κB signalling ...... tant TERT promoter activation.

@en

prefLabel

Non-canonical NF-κB signalling ...... tant TERT promoter activation.

@ast

Non-canonical NF-κB signalling ...... tant TERT promoter activation.

@en

P1433

Q36635311-95DC36D3-7A86-48AC-A0A9-5DD72C769661

P1476

Q36635311-F2726E11-F14C-4048-9986-155AF5FB1261

P2093

Q36635311-0A181009-1CE3-4EA0-AA8B-5F5D67C0BCE7

Q36635311-1744ECCA-90C5-4B6B-B87A-FECCE6A7A8F2

Q36635311-258C833E-C528-4B5A-8C28-373121DA731F

Q36635311-713919BA-572C-42E1-9E64-E4E8DF1CE36F

Q36635311-788A2194-9472-4651-B861-7D31CBA7282A

Q36635311-8BD7D2F7-8469-40F7-B0B3-697562A623AE

Q36635311-AD42DA2D-126F-4AAC-A56C-39BB31C8F798

Q36635311-C1A707C2-544D-4E9D-BDED-A3E5210CC982

Q36635311-E14A7A02-E9D7-439A-8DEF-A797D329F17C

Q36635311-E6D5AE9C-D2E1-4F70-8AEE-5F35D1CFE93F

P2860

Q36635311-045B2A4D-AC1A-47BB-9FE0-1702C94904DB

Q36635311-0499D884-D370-4D1F-AA69-C58F5334DB5D

Q36635311-05CC9621-813C-41C8-8A5F-1F7EF23A7515

Q36635311-1428A5D4-8D52-46A8-A2B9-ABE75264833A

Q36635311-16CCEF2C-F53A-412F-9CEB-BC06EAF8772B

Q36635311-1C2C3FBE-AAAA-495A-AC5A-AA16D1DCECD3

Q36635311-1E02A58B-2173-4365-B9FB-DBC1CD1BAF35

Q36635311-1F7ACEA9-E463-43AE-90DC-2DA31ED401F7

Q36635311-20D2E2DC-A1F1-4B00-AE79-E8B01CAE665E

Q36635311-2966F2E6-95BE-47F5-8D17-81AA3550ABEC

P2888

Q36635311-576C52A9-AF8D-4824-821A-9FB64C5F24E6

P304

Q36635311-1C078302-8C02-4521-A1A2-6086724279C5

P31

Q36635311-8D930452-B04E-4FA8-8CBC-CC96622298F5

P356

Q36635311-4913DF89-4184-4477-977C-A9BCF1C36EF1

P433

Q36635311-ED59BAF5-188A-4FD6-8A8F-60F006A7470D

P478

Q36635311-A0C00997-7D2A-43BC-BBFB-B55311A0EF4D

P50

Q36635311-6CA10174-EE7F-4CFE-BCE5-F3145FFCDD4C

Q36635311-983A8710-0B7B-4FC0-9427-D609DDD0D5CF

P577

Q36635311-89AEDC9F-618A-43D9-BBAF-6941DA6B898C

P698

Q36635311-F0D8CB95-6DE4-48F0-B83C-99399B0DA0A1

P921

Q36635311-B0B2DE44-C6A0-47C3-B65C-E42033860AB1

P932

Q36635311-945DF103-FB25-4F54-91CB-5776251CF2C3

P356

P1433

Nature Cell Biology

P1476

Non-canonical NF-κB signalling ...... utant TERT promoter activation

@en

P2093

Anandhkumar Raju

http://www.w3.org/2001/XMLSchema#string

Daniel G Tenen

http://www.w3.org/2001/XMLSchema#string

Hui Shan Cheng

http://www.w3.org/2001/XMLSchema#string

Jun Li

http://www.w3.org/2001/XMLSchema#string

Manikandan Lakshmanan

http://www.w3.org/2001/XMLSchema#string

Mengfeng Li

http://www.w3.org/2001/XMLSchema#string

Qi-Ling Zhou

http://www.w3.org/2001/XMLSchema#string

Shi-Yuan Cheng

http://www.w3.org/2001/XMLSchema#string

Shyam Prabhakar

http://www.w3.org/2001/XMLSchema#string

Vinay Tergaonkar

http://www.w3.org/2001/XMLSchema#string

P2860

Genome engineering using the CRISPR-Cas9 system

An integrated encyclopedia of DNA elements in the human genome

Hallmarks of Cancer: The Next Generation

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

A NIK-IKKα module expands ErbB2-induced tumor-initiating cells by stimulating nuclear export of p27/Kip1

Human telomerase and its regulation

Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers

Physical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cells

Molecular mechanisms of ETS transcription factor-mediated tumorigenesis

Structural basis of Ets1 cooperative binding to palindromic sequences on stromelysin-1 promoter DNA

P2888

P304

1327-1338

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NCB3240

http://www.w3.org/2001/XMLSchema#string

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

17

http://www.w3.org/2001/XMLSchema#string

P50

Kai-Hsiang Chuang

Prashant Chandrasekharan

P577

2015-09-21T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

26389665

http://www.w3.org/2001/XMLSchema#string

P921

P932

4772727

http://www.w3.org/2001/XMLSchema#string