Intricate interplay between astrocytes and motor neurons in ALS. - Wikidata - awgldk - TriplyDB

Intricate interplay between astrocytes and motor neurons in ALS.

Intricate interplay between astrocytes and motor neurons in ALS.

http://www.wikidata.org/entity/Q36637458

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Microglia centered pathogenesis in ALS: insights in cell interconnectivity Blood-CNS Barrier Impairment in ALS patients versus an animal model ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease Altered Metabolic Profiles Associate with Toxicity in SOD1G93A Astrocyte-Neuron Co-Cultures.CNS-targeted glucocorticoid reduces pathology in mouse model of amyotrophic lateral sclerosis Induction of COX-2-PGE2 synthesis by activation of the MAPK/ERK pathway contributes to neuronal death triggered by TDP-43-depleted microglia.ALS mutations in TLS/FUS disrupt target gene expression.Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration Signaling pathways regulating neuron-glia interaction and their implications in Alzheimer's disease.Postactivation depression of the Ia EPSP in motoneurons is reduced in both the G127X SOD1 model of amyotrophic lateral sclerosis and in aged mice.A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies The multifaceted role of glial cells in amyotrophic lateral sclerosis.Glial cells in amyotrophic lateral sclerosis Astrocytes in neurodegenerative disease.Translational potential of astrocytes in brain disorders.Glia-neuron interactions in neurological diseases: Testing non-cell autonomy in a dish.Exosomes from NSC-34 Cells Transfected with hSOD1-G93A Are Enriched in miR-124 and Drive Alterations in Microglia Phenotype.Single-cell topological RNA-seq analysis reveals insights into cellular differentiation and development.The non-cell-autonomous component of ALS: new in vitro models and future challenges.Extracellular wildtype and mutant SOD1 induces ER-Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells.Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1.Massive transcriptome sequencing of human spinal cord tissues provides new insights into motor neuron degeneration in ALS Biological markers of mesenchymal stromal cells as predictors of response to autologous stem cell transplantation in patients with amyotrophic lateral sclerosis: an investigator-initiated trial and in vivo study.Unpicking neurodegeneration in a dish with human pluripotent stem cells: one cell type at a time.Let's make microglia great again in neurodegenerative disorders.The Importance of Non-neuronal Cell Types in hiPSC-Based Disease Modeling and Drug Screening.Diversity of astroglial responses across human neurodegenerative disorders and brain aging.Distinct roles for motor neuron autophagy early and late in the SOD1G93A mouse model of ALS.Astroglial transcriptome dysregulation in early disease of an ALS mutant SOD1 mouse model.Senataxin Mutation Reveals How R-Loops Promote Transcription by Blocking DNA Methylation at Gene Promoters.Correlating serum micrornas and clinical parameters in amyotrophic lateral sclerosis.Exploring microRNA Biomarker for Amyotrophic Lateral Sclerosis.Safety and efficacy of human embryonic stem cell-derived astrocytes following intrathecal transplantation in SOD1G93A and NSG animal models.RNA-Seq Analysis of Spinal Cord Tissues from hPFN1 Transgenic Mouse Model of ALS at Pre-symptomatic and End-Stages of Disease Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons

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Intricate interplay between astrocytes and motor neurons in ALS.

http://www.wikidata.org/entity/Q36637458

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2013年论文

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2013年论文

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name

Intricate interplay between astrocytes and motor neurons in ALS.

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Intricate interplay between astrocytes and motor neurons in ALS.

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Intricate interplay between astrocytes and motor neurons in ALS.

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Intricate interplay between astrocytes and motor neurons in ALS.

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Intricate interplay between astrocytes and motor neurons in ALS.

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Intricate interplay between astrocytes and motor neurons in ALS.

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Chiamaka Nwakeze

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Florencia Pauli-Behn

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Hemali P Phatnani

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Juan Carlos Tapia

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Kimberly M Newberry

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Michael Muratet

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Monica A Carrasco

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Paolo Guarnieri

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Richard M Myers

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Sarah K Meadows

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P2860

Bioconductor: open software development for computational biology and bioinformatics

Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress

SMART, a simple modular architecture research tool: identification of signaling domains

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

Molecular dissection of reactive astrogliosis and glial scar formation

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

The role of astrocyte-secreted matricellular proteins in central nervous system development and function

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

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amyotrophic lateral sclerosis

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