Alternative genetic pathways in colorectal carcinogenesis.
about
Mutations in APC, CTNNB1 and K-ras genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study.HPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancersElevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cellsAssociation between cigarette smoking, APC mutations and the risk of developing sporadic colorectal adenomas and carcinomas.Parallel routes of human carcinoma development: implications of the age-specific incidence dataDeregulation of apoptosis in colorectal carcinoma: theoretical and therapeutic implications.Colorectal cancer: molecules and populations.Allelotyping identification of genomic alterations in rectal chromosomally unstable tumors without preoperative treatment.Hyperplastic polyps and DNA microsatellite unstable cancers of the colorectum.Comethylation of p16 and MGMT genes in colorectal carcinoma: correlation with clinicopathological features and prognostic valueCarcinogenesis in the GI tract: from morphology to genetics and back again.Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas.Evolution of colorectal cancer: change of pace and change of direction.Are there two sides to colorectal cancer?Pathogenesis and clinical management of hereditary non-polyposis colorectal cancer.APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits"Genetic epidemiology of mutated K-ras proto-oncogene, altered suppressor genes, and microsatellite instability in colorectal adenomasNeoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum.APC mutation and tumour budding in colorectal cancer.Methylation patterns define two types of hyperplastic polyp associated with colorectal cancerFeatures of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesisAccumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences.Pancreatic adenocarcinomas with DNA replication errors (RER+) are associated with wild-type K-ras and characteristic histopathology. Poor differentiation, a syncytial growth pattern, and pushing borders suggest RER+Inverse relationship between microsatellite instability and K-ras and p53 gene alterations in colon cancerEffects of dietary intake and genetic factors on hypermethylation of the hMLH1 gene promoter in gastric cancer.Expression Profiles in Stage II Colon Cancer According to APC Gene Status.Hyperplastic polyps, serrated adenomas, and the serrated polyp neoplasia pathway.Molecular classification and correlates in colorectal cancerSynergy between docosahexaenoic acid and butyrate elicits p53-independent apoptosis via mitochondrial Ca(2+) accumulation in colonocytes.Epigenetic phenotypes distinguish microsatellite-stable and -unstable colorectal cancers.Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status.Extensive molecular screening for hereditary non-polyposis colorectal cancerContrasting molecular pathology of colorectal carcinoma in Egyptian and Western patientsActivity (transcription) of the genes for MLH1, MSH2 and p53 in sporadic colorectal tumours with micro-satellite instability.Clinicopathological and molecular characteristics of gastric and colorectal carcinomas in the elderly.Predictive and prognostic factors in colorectal cancer: a personalized approach.Mutational inactivation of the proapoptotic gene BAX confers selective advantage during tumor clonal evolution.Small bowel adenocarcinoma phenotyping, a clinicobiological prognostic study.Impact of chromosome 17q deletion in the primary lesion of colorectal cancer on liver metastasis.A unique profile of adenomatous polyposis coli gene mutations in Iranian patients suffering sporadic colorectal cancer.
P2860
Q21261222-C616A6F4-F4F3-427D-AC47-07114D578B69Q24546185-0987765A-2AAF-490E-927F-D49BE1B520EDQ28592033-E1A917BC-6C9A-4648-A213-0F2EA8E5848BQ33236882-D1605B67-5F1B-4A76-AB7D-3FC3148BF887Q33506089-02401BD1-7943-459C-A7C2-F5BD2D08A604Q33536031-56089356-5DEF-420D-9EC0-4EE1465F71A7Q33652932-6C391C0D-525F-4CE2-A519-C6336C63F1DBQ33721457-2AE1763F-372C-4D4C-9856-C51C02DE6CEBQ34049950-2650E252-BF01-46A2-ADD4-01104B64233FQ34099517-43BE16CC-4071-46FC-B3F8-E99916A9D0EEQ34194253-072F8489-9C3D-42E4-8AE1-9D31649B700DQ34355726-FF7F276F-48E4-486C-B63F-4F7B77EE8109Q34622521-0A61755A-322B-4F1E-9904-E051ACAC886BQ34822109-59FD62AF-164D-4628-B4B2-907667F4150BQ34975960-692920B6-8651-4599-B575-5D10040CDC5BQ35110017-1170232D-2F89-4A40-AB4E-65963F1E9854Q35355359-CFD2E172-AAAD-42BF-8F8C-844D164481EDQ35360361-DCCBB299-6F67-4FE1-8975-51B5EE9F4EFCQ35586573-F1B3A23E-809A-47CF-B148-7AF7F7DC46C3Q35596441-C1D477B7-C68D-48BA-9B7C-20D1E5FC4686Q35747184-D7B75FF6-0CA2-4A8C-9C50-8B0A119ECAF9Q35753544-E9C24CB5-57F0-43E5-97F0-C760C6EFA9E1Q35765148-D1F8A9FD-D76C-480F-B5D3-0AC0C4543AA4Q35842039-7F893E55-1D55-4848-900A-76D595811C0EQ35858963-0466F37D-C20F-4545-B8B0-D4958057138FQ35882231-73A07B23-2673-4C96-BA1A-829C939F1FA6Q35956892-A9A13BEA-3F62-4506-B2BD-B4AA6E01E228Q36329300-2A55EC7E-16DB-4F34-B63E-29A5E06879B4Q36346859-F510D25D-0299-4B63-9082-F4D5E285E44BQ36549885-CE637F32-6ACC-4072-B704-7B8C41AB01DBQ36641418-A8E52368-A4AC-4EF1-B862-A7D0BFF10870Q36641429-D122076C-73FD-4A48-B54D-280E748A7E57Q36643467-BA22FBA8-5827-411A-924C-85F98C323E0EQ36694101-944C4A29-6F68-4E80-BE93-EA6D880C8BE4Q36836007-27BA2E4E-98B2-47D5-968B-19EAB194DFD4Q37132653-AE04437E-4460-40F0-A1D5-68045D69F00EQ37264027-4AB322BD-1B35-40BB-8206-02FE9C59A801Q37385280-C4498FE6-C86C-4244-8AE0-EDBC92EDFE40Q37581942-9266AC73-EECA-4E82-AD9E-A7A1478744D3Q37600814-079FF221-9482-4FC1-8E4B-E39332E97EFD
P2860
Alternative genetic pathways in colorectal carcinogenesis.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Alternative genetic pathways in colorectal carcinogenesis.
@ast
Alternative genetic pathways in colorectal carcinogenesis.
@en
type
label
Alternative genetic pathways in colorectal carcinogenesis.
@ast
Alternative genetic pathways in colorectal carcinogenesis.
@en
prefLabel
Alternative genetic pathways in colorectal carcinogenesis.
@ast
Alternative genetic pathways in colorectal carcinogenesis.
@en
P2093
P2860
P356
P1476
Alternative genetic pathways in colorectal carcinogenesis
@en
P2093
R J Salmon
S Olschwang
Y De Rycke
P2860
P304
12122-12127
P356
10.1073/PNAS.94.22.12122
P407
P577
1997-10-01T00:00:00Z