Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity.
about
Clinically significant drug-drug interactions involving opioid analgesics used for pain treatment in patients with cancer: a systematic reviewA review of pharmacological interactions between HIV or hepatitis C virus medications and opioid agonist therapy: implications and management for clinical practiceEthnic and genetic factors in methadone pharmacokinetics: a population pharmacokinetic studyEfflux transporters- and cytochrome P-450-mediated interactions between drugs of abuse and antiretrovirals.Automated radiochemical synthesis and biodistribution of [¹¹C]l-α-acetylmethadol ([¹¹C]LAAM).Drug interactions associated with methadone, buprenorphine, cocaine, and HIV medications: implications for pregnant women.Complex drug interactions of the HIV protease inhibitors 3: effect of simultaneous or staggered dosing of digoxin and ritonavir, nelfinavir, rifampin, or bupropionDrug interactions of clinical importance among the opioids, methadone and buprenorphine, and other frequently prescribed medications: a review.Cyclosporine-inhibitable cerebral drug transport does not influence clinical methadone pharmacodynamics.Methadone Pharmacogenetics: CYP2B6 Polymorphisms Determine Plasma Concentrations, Clearance, and MetabolismSensitivity of intravenous and oral alfentanil and pupillary miosis as minimal and noninvasive probes for hepatic and first-pass CYP3A induction.Perioperative pharmacokinetics of methadone in adolescents.Concurrent assessment of hepatic and intestinal cytochrome P450 3A activities using deuterated alfentanilLack of indinavir effects on methadone disposition despite inhibition of hepatic and intestinal cytochrome P4503A (CYP3A).Mechanism of efavirenz influence on methadone pharmacokinetics and pharmacodynamicsRole of cytochrome P4502B6 in methadone metabolism and clearance.Influence of drug transport proteins on the pharmacokinetics and drug interactions of HIV protease inhibitors.Methadone induces the expression of hepatic drug-metabolizing enzymes through the activation of pregnane X receptor and constitutive androstane receptor.Cytochrome P4503A does not mediate the interaction between methadone and ritonavir-lopinavir.Mechanism of autoinduction of methadone N-demethylation in human hepatocytes.Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects.Methadone, buprenorphine, and street drug interactions with antiretroviral medications'False-positive' and 'false-negative' test results in clinical urine drug testing.Methadone: a review of drug-drug and pathophysiological interactions.Metabolic and toxicological considerations of the opioid replacement therapy and analgesic drugs: methadone and buprenorphine.Pharmacogenomics of methadone maintenance treatment.Pharmacokinetics and analgesic effects of methadone in children and adults with sickle cell disease.Intraoperative methadone: rediscovery, reappraisal, and reinvigoration?Pharmacokinetic interactions between darunavir/ritonavir and opioid maintenance therapy using methadone or buprenorphine/naloxone.Current Concepts in Methadone Metabolism and Transport.Genetic polymorphisms in CYP3A4 are associated with withdrawal symptoms and adverse reactions in methadone maintenance patients.Drug interactions with methadone: Time to revise the product label.
P2860
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P2860
Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Methadone metabolism and clear ...... hrome P4503A (CYP3A) activity.
@ast
Methadone metabolism and clear ...... hrome P4503A (CYP3A) activity.
@en
type
label
Methadone metabolism and clear ...... hrome P4503A (CYP3A) activity.
@ast
Methadone metabolism and clear ...... hrome P4503A (CYP3A) activity.
@en
prefLabel
Methadone metabolism and clear ...... hrome P4503A (CYP3A) activity.
@ast
Methadone metabolism and clear ...... hrome P4503A (CYP3A) activity.
@en
P2093
P2860
P1476
Methadone metabolism and clear ...... hrome P4503A (CYP3A) activity.
@en
P2093
Alysa Walker
Christine Hoffer
Dale Whittington
Evan D Kharasch
Pamela Sheffels Bedynek
P2860
P304
P356
10.1016/J.DRUGALCDEP.2008.12.009
P577
2009-02-18T00:00:00Z