A "string-of-beads" vaccine, comprising linked minigenes, confers protection from lethal-dose virus challenge.
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Advanced vaccine candidates for Lassa feverHIV-1 Vaccine Trials: Evolving Concepts and DesignsFunctional analysis of amino acid residues encompassing and surrounding two neighboring H-2Db-restricted cytotoxic T-lymphocyte epitopes in simian virus 40 tumor antigen.High throughput T epitope mapping and vaccine developmentDNA vaccination against Theiler's murine encephalomyelitis virus leads to alterations in demyelinating disease.An Approach for a Synthetic CTL Vaccine Design against Zika Flavivirus Using Class I and Class II Epitopes Identified by Computer ModelingDNA immunization with minigenes: low frequency of memory cytotoxic T lymphocytes and inefficient antiviral protection are rectified by ubiquitination.Immunization with a single major histocompatibility complex class I-restricted cytotoxic T-lymphocyte recognition epitope of herpes simplex virus type 2 confers protective immunity.Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model.Delivery of multiple epitopes by recombinant detoxified adenylate cyclase of Bordetella pertussis induces protective antiviral immunity.Minimal epitopes expressed in a recombinant polyepitope protein are processed and presented to CD8+ cytotoxic T cells: implications for vaccine design.Molecular anatomy and number of antigen specific CD8 T cells required to cause type 1 diabetesA highly optimized DNA vaccine confers complete protective immunity against high-dose lethal lymphocytic choriomeningitis virus challenge.A recombinant minigene vaccine containing a nonameric cytotoxic-T-lymphocyte epitope confers limited protection against Listeria monocytogenes infectionVaccinia virus infection of mature dendritic cells results in activation of virus-specific naïve CD8+ T cells: a potential mechanism for direct presentation.HLA-A2-restricted protection against lethal lymphocytic choriomeningitis.Antiviral protective immunity induced by major histocompatibility complex class I molecule-restricted viral T-lymphocyte epitopes inserted in various positions in immunologically self and nonself proteins.Attenuated Mengo virus: a new vector for live recombinant vaccines.Emergence of virus escape mutants after immunization with epitope vaccine.CD8+ T-cell epitopes within the surface glycoprotein of a neurotropic coronavirus and correlation with pathogenicity.Neonatal DNA immunization with a plasmid encoding an internal viral protein is effective in the presence of maternal antibodies and protects against subsequent viral challenge.Changes in functional but not structural avidity during differentiation of CD8+ effector cells in vivo after virus infectionVirus-lymphoid cell interactions.Memory CD8+ T cells specific for a single immunodominant or subdominant determinant induced by peptide-dendritic cell immunization protect from an acute lethal viral disease.Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity.CD8 T cell memory in B cell-deficient mice.The search for animal models for Lassa fever vaccine developmentProtection against lethal lymphocytic choriomeningitis virus (LCMV) infection by immunization of mice with an influenza virus containing an LCMV epitope recognized by cytotoxic T lymphocytesSimian virus 40 T antigen as a carrier for the expression of cytotoxic T-lymphocyte recognition epitopes.An anti-lymphocytic choriomeningitis virus ribozyme expressed in tissue culture cells diminishes viral RNA levels and leads to a reduction in infectious virus yield.Protective anti-tumor immunity induced by vaccination with recombinant adenoviruses encoding multiple tumor-associated cytotoxic T lymphocyte epitopes in a string-of-beads fashionOptimized DNA vaccines to specifically induce therapeutic CD8 T cell responses against autochthonous breast tumors.High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion.T-cell vaccine strategies for human immunodeficiency virus, the virus with a thousand faces.Common antiviral cytotoxic t-lymphocyte epitope for diverse arenaviruses.CD4(+) T cells induced by a DNA vaccine: immunological consequences of epitope-specific lysosomal targeting.Two overlapping subdominant epitopes identified by DNA immunization induce protective CD8(+) T-cell populations with differing cytolytic activities.Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope.Immunodominance in virus-induced CD8(+) T-cell responses is dramatically modified by DNA immunization and is regulated by gamma interferon.Polymorphism within the herpes simplex virus (HSV) ribonucleotide reductase large subunit (ICP6) confers type specificity for recognition by HSV type 1-specific cytotoxic T lymphocytes.
P2860
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P2860
A "string-of-beads" vaccine, comprising linked minigenes, confers protection from lethal-dose virus challenge.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
A "string-of-beads" vaccine, c ...... m lethal-dose virus challenge.
@ast
A "string-of-beads" vaccine, c ...... m lethal-dose virus challenge.
@en
type
label
A "string-of-beads" vaccine, c ...... m lethal-dose virus challenge.
@ast
A "string-of-beads" vaccine, c ...... m lethal-dose virus challenge.
@en
prefLabel
A "string-of-beads" vaccine, c ...... m lethal-dose virus challenge.
@ast
A "string-of-beads" vaccine, c ...... m lethal-dose virus challenge.
@en
P2093
P2860
P1433
P1476
A "string-of-beads" vaccine, c ...... m lethal-dose virus challenge.
@en
P2093
J L Whitton
M B Oldstone
P2860
P304
P407
P577
1993-01-01T00:00:00Z