Plasticity of quaternary structure: twenty-two ways to form a LacI dimer.
about
Amino acid positions subject to multiple coevolutionary constraints can be robustly identified by their eigenvector network centrality scoresAlloRep: A Repository of Sequence, Structural and Mutagenesis Data for the LacI/GalR Transcription RegulatorsData on publications, structural analyses, and queries used to build and utilize the AlloRep database.Comparing the functional roles of nonconserved sequence positions in homologous transcription repressors: implications for sequence/function analyses.The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis.Engineering soluble monomeric streptavidin with reversible biotin binding capability.Allosteric transition pathways in the lactose repressor protein core domains: asymmetric motions in a homodimer.Fine-tuning function: correlation of hinge domain interactions with functional distinctions between LacI and PurRSubdividing repressor function: DNA binding affinity, selectivity, and allostery can be altered by amino acid substitution of nonconserved residues in a LacI/GalR homologue.Experimental identification of specificity determinants in the domain linker of a LacI/GalR protein: bioinformatics-based predictions generate true positives and false negatives.Engineering an allosteric transcription factor to respond to new ligands.Mispair-specific recruitment of the Mlh1-Pms1 complex identifies repair substrates of the Saccharomyces cerevisiae Msh2-Msh3 complex.Functional consequences of exchanging domains between LacI and PurR are mediated by the intervening linker sequence.Altering residues N125 and D149 impacts sugar effector binding and allosteric parameters in Escherichia coli lactose repressor.Deconstruction of complex protein signaling switches: a roadmap toward engineering higher-order gene regulators.Easy Identification of Residues Involved on Structural Differences Between Nonphosphorylated and Phosphorylated CDK2Cyclin A Complexes Using Two-Dimensional Networks.A novel molecular switchResmap: automated representation of macromolecular interfaces as two-dimensional networks.Structure-guided approach to site-specific fluorophore labeling of the lac repressor LacI.
P2860
Q30380675-F6E481C2-1593-4BD0-B536-2911644C74FDQ30998099-F085F658-6A7B-4335-9445-A8E8B5D52FBEQ31120856-BE072492-22C9-4752-A059-4A0E6C8107CEQ33618402-D7179904-FCF9-43FD-A420-8AB672D73543Q33952780-BCC99C32-6872-460E-89E1-AA0810C3E2C3Q34412508-19C994C4-3008-42F6-9231-731BA244380EQ36631435-23F3D148-AB59-4974-AA56-68A30D973B2FQ36639184-213EABCF-47F7-4AF3-98F1-B82C709E6099Q36923736-19E9761E-8F07-441C-88CC-3D71125250B9Q36978145-3B9FFD58-1587-48F6-B21F-4E97771C5EEEQ37002971-38350FB1-A5EB-4807-8800-12A59BD21570Q37691675-E30AD532-6639-4192-B367-388438334E6AQ38302702-C07D2083-8063-4CBF-9FFF-9FAB8EED7318Q38331796-510DF08A-2C22-4A3B-BFBC-70C72F06E804Q39129495-7BDF6638-426E-429A-9721-03EC7E4370EBQ39531357-88DFD78E-1798-40A8-814E-7CE87FD6BC36Q42640969-F30DB766-F67C-4375-9A84-E39601411E8AQ51972918-C87175A1-E16C-4202-AD23-64768E57548AQ55384281-7C41D48E-2D4C-49D4-B62D-004CBEAD67E0
P2860
Plasticity of quaternary structure: twenty-two ways to form a LacI dimer.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Plasticity of quaternary structure: twenty-two ways to form a LacI dimer.
@ast
Plasticity of quaternary structure: twenty-two ways to form a LacI dimer.
@en
type
label
Plasticity of quaternary structure: twenty-two ways to form a LacI dimer.
@ast
Plasticity of quaternary structure: twenty-two ways to form a LacI dimer.
@en
prefLabel
Plasticity of quaternary structure: twenty-two ways to form a LacI dimer.
@ast
Plasticity of quaternary structure: twenty-two ways to form a LacI dimer.
@en
P2093
P2860
P356
P1433
P1476
Plasticity of quaternary structure: twenty-two ways to form a LacI dimer.
@en
P2093
D R Wycuff
K Shive Matthews
L Swint-Kruse
P2860
P304
P356
10.1110/PS.35801
P577
2001-02-01T00:00:00Z