Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein. - Wikidata - awgldk - TriplyDB

Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein.

Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein.

http://www.wikidata.org/entity/Q36640417

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The role of oxidative stress in Parkinson's disease The complex relationships between microglia, alpha-synuclein, and LRRK2 in Parkinson's disease Seeking a mechanism for the toxicity of oligomeric α-synuclein MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration Towards translational therapies for multiple system atrophy Evidence of inflammatory system involvement in Parkinson's disease.Understanding the addiction cycle: a complex biology with distinct contributions of genotype vs. sex at each stage.Pathways to Parkinsonism Redux: convergent pathobiological mechanisms in genetics of Parkinson's disease.Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies.Lithium prevents parkinsonian behavioral and striatal phenotypes in an aged parkin mutant transgenic mouse model.Fractalkine over expression suppresses α-synuclein-mediated neurodegeneration Dopaminergic Toxin 1-Methyl-4-Phenylpyridinium, Proteins α-Synuclein and Glia Maturation Factor Activate Mast Cells and Release Inflammatory Mediators.Can the disease course in Parkinson's disease be slowed?Derivation, Characterization, and Neural Differentiation of Integration-Free Induced Pluripotent Stem Cell Lines from Parkinson's Disease Patients Carrying SNCA, LRRK2, PARK2, and GBA Mutations Alpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T Mutant Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders.Suppression of MAPK attenuates neuronal cell death induced by activated glia-conditioned medium in alpha-synuclein overexpressing SH-SY5Y cells.Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases.Nrf2--a therapeutic target for the treatment of neurodegenerative diseases.Microglial-neuronal interactions during neurodegenerative diseases.Repurposing the NRF2 Activator Dimethyl Fumarate as Therapy Against Synucleinopathy in Parkinson's Disease Toll-like receptor 2 is increased in neurons in Parkinson's disease brain and may contribute to alpha-synuclein pathology.Review: microglia in protein aggregation disorders: friend or foe?Neuropathology of multiple system atrophy: new thoughts about pathogenesis.Neuronal MHC-I expression and its implications in synaptic function, axonal regeneration and Parkinson's and other brain diseases Intranasal delivery of bone marrow-derived mesenchymal stem cells, macrophages, and microglia to the brain in mouse models of Alzheimer's and Parkinson's disease.Multiple system atrophy: pathogenic mechanisms and biomarkers.Neurotoxicity effects of atrazine-induced SH-SY5Y human dopaminergic neuroblastoma cells via microglial activation.l-DOPA-induced dyskinesia in Parkinson's disease: Are neuroinflammation and astrocytes key elements?Targeting Microglial Activation States as a Therapeutic Avenue in Parkinson's Disease.α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology.Early Alzheimer's and Parkinson's disease pathology in urban children: Friend versus Foe responses--it is time to face the evidence.Brain and Peripheral Atypical Inflammatory Mediators Potentiate Neuroinflammation and Neurodegeneration.Isolation of cortical microglia with preserved immunophenotype and functionality from murine neonates.The Mechanisms of Traditional Chinese Medicine Underlying the Prevention and Treatment of Parkinson's Disease.α-Mangostin Inhibits α-Synuclein-Induced Microglial Neuroinflammation and Neurotoxicity.Ceruloplasmin potentiates nitric oxide synthase activity and cytokine secretion in activated microglia.The neuropathology of multiple system atrophy and its therapeutic implications.NADPH oxidases in Parkinson's disease: a systematic review.Glia activation and its role in oxidative stress.

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P2860

Microglial activation and antioxidant responses induced by the Parkinson's disease protein α-synuclein.

http://www.wikidata.org/entity/Q36640417

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Microglial activation and anti ...... s disease protein α-synuclein.

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Microglial activation and anti ...... s disease protein α-synuclein.

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Microglial activation and anti ...... s disease protein α-synuclein.

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S11481-012-9401-0

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Journal of Neuroimmune Pharmacology

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Microglial activation and anti ...... s disease protein α-synuclein.

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Dawn Béraud

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Delinda A Johnson

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Howard J Federoff

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Jeffrey A Johnson

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Jordan Trecki

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Kathleen A Maguire-Zeiss

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Mika Shimoji

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Sergey Chasovskikh

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Timothy R Mhyre

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P2860

Parkinson's disease: from monogenic forms to genetic susceptibility factors

Mutant and wild-type alpha-synuclein interact with mitochondrial cytochrome C oxidase

Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy

A progressive mouse model of Parkinson's disease: the Thy1-aSyn ("Line 61") mice

alpha-Synuclein locus triplication causes Parkinson's disease

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s11481-012-9401-0

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94-117

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1

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8

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Hannah A Hathaway

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2012-10-10T00:00:00Z

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232231010

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23054368

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Parkinson's disease

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3582877

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