The Gordon Wilson lecture. Mutations in type I procollagen genes. An explanation for brittle bones and a paradigm for other diseases of connective tissue.

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The Gordon Wilson lecture. Mutations in type I procollagen genes. An explanation for brittle bones and a paradigm for other diseases of connective tissue.

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1989 nî lūn-bûn

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1989年の論文

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1989年論文

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1989年論文

@zh-hant

1989年論文

@zh-hk

1989年論文

@zh-mo

1989年論文

@zh-tw

1989年论文

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1989年论文

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1989年论文

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name

The Gordon Wilson lecture. Mut ...... diseases of connective tissue.

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The Gordon Wilson lecture. Mut ...... diseases of connective tissue.

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The Gordon Wilson lecture. Mut ...... diseases of connective tissue.

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The Gordon Wilson lecture. Mut ...... diseases of connective tissue.

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The Gordon Wilson lecture. Mut ...... diseases of connective tissue.

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The Gordon Wilson lecture. Mut ...... diseases of connective tissue.

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P1476

The Gordon Wilson lecture. Mut ...... diseases of connective tissue

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P2093

D J Prockop

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P2860

Cloning a cDNA for the pro-alpha 2 chain of human type I collagen

Perinatal lethal osteogenesis imperfecta (OI type II): a biochemically heterogeneous disorder usually due to new mutations in the genes for type I collagen.

Reduced secretion of structurally abnormal type I procollagen in a form of osteogenesis imperfecta.

The clinical features of homozygous alpha 2(I) collagen deficient osteogenesis imperfecta.

A substitution of cysteine for glycine 748 of the alpha 1 chain produces a kink at this site in the procollagen I molecule and an altered N-proteinase cleavage site over 225 nm away.

Nucleotide sequences of complementary deoxyribonucleic acids for the pro alpha 1 chain of human type I procollagen. Statistical evaluation of structures that are conserved during evolution.

Cleavage of type I and type II procollagens by type I/II procollagen N-proteinase. Correlation of kinetic constants with the predicted conformations of procollagen substrates.

Synthesis and processing of a type I procollagen containing shortened pro-alpha 1(I) chains by fibroblasts from a patient with osteogenesis imperfecta

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70-80

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scholarly article

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100

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1989-01-01T00:00:00Z

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3269104

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connective tissue

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2376450

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