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The vaccinia virus soluble alpha/beta interferon (IFN) receptor binds to the cell surface and protects cells from the antiviral effects of IFN.Deficiency in Th2 cytokine responses exacerbate orthopoxvirus infectionEvidence for Persistence of Ectromelia Virus in Inbred Mice, Recrudescence Following Immunosuppression and Transmission to Naïve MiceStructure and mechanism of IFN- antagonism by an orthopoxvirus IFN- -binding proteinImmune requirements of post-exposure immunization with modified vaccinia Ankara of lethally infected miceIdentification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccinesA role for NKG2D in NK cell-mediated resistance to poxvirus disease.Surviving mousepox infection requires the complement systemThe interferon-inducible chemokines MuMig and Crg-2 exhibit antiviral activity In vivo.CD8 T cells use IFN-γ to protect against the lethal effects of a respiratory poxvirus infection.Identification of nitric oxide synthase 2 as an innate resistance locus against ectromelia virus infection.Expression of mouse interleukin-4 by a recombinant ectromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox.Interferon function is not required for recovery from a secondary poxvirus infection.Ectromelia virus inhibitor of complement enzymes protects intracellular mature virus and infected cells from mouse complement.Age-dependent susceptibility to a viral disease due to decreased natural killer cell numbers and traffickingRapid expansion of CD8+ T cells in wild-type and type I interferon receptor-deficient mice correlates with protection after low-dose emergency immunization with modified vaccinia virus Ankara.Obligatory requirement for antibody in recovery from a primary poxvirus infectionN1L is an ectromelia virus virulence factor and essential for in vivo spread upon respiratory infection.Smallpox vaccines: targets of protective immunity.Polarized type 1 cytokine response and cell-mediated immunity determine genetic resistance to mousepox.Glycosaminoglycans mediate retention of the poxvirus type I interferon binding protein at the cell surface to locally block interferon antiviral responses.Fas/FasL pathway participates in regulation of antiviral and inflammatory response during mousepox infection of lungsPreferential replication of vaccinia virus in the ovaries is independent of immune regulation through IL-10 and TGF-βThe ectromelia virus SPI-2 protein causes lethal mousepox by preventing NK cell responsesIL-18 binding and inhibition of interferon gamma induction by human poxvirus-encoded proteins.Differential pathogenesis of lethal mousepox in congenic DBA/2 mice implicates natural killer cell receptor NKR-P1 in necrotizing hepatitis and the fifth component of complement in recruitment of circulating leukocytes to spleen.Poxvirus-encoded gamma interferon binding protein dampens the host immune response to infectionInduction of natural killer cell responses by ectromelia virus controls infection.Ly49h-deficient C57BL/6 mice: a new mouse cytomegalovirus-susceptible model remains resistant to unrelated pathogens controlled by the NK gene complex.Gamma interferon-induced, nitric oxide-mediated inhibition of vaccinia virus replicationEctromelia virus RING finger protein is localized in virus factories and is required for virus replication in macrophagesGamma interferon expression during acute and latent nervous system infection by herpes simplex virus type 1.A recombinant vaccinia virus encoding inducible nitric oxide synthase is attenuated in vivo.Different roles for CD4+ and CD8+ T lymphocytes and macrophage subsets in the control of a generalized virus infection.Distinct organ-dependent mechanisms for the control of murine cytomegalovirus infection by natural killer cells.Increased protection from vaccinia virus infection in mice genetically prone to lymphoproliferative disorders.Interaction between unrelated viruses during in vivo co-infection to limit pathology and immunityPerforin-dependent CD4+ T-cell cytotoxicity contributes to control a murine poxvirus infection.Lethal monkeypox virus infection of CAST/EiJ mice is associated with a deficient gamma interferon responseEnhanced resistance in STAT6-deficient mice to infection with ectromelia virus
P2860
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P2860
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Importance of interferons in recovery from mousepox
@ast
Importance of interferons in recovery from mousepox
@en
type
label
Importance of interferons in recovery from mousepox
@ast
Importance of interferons in recovery from mousepox
@en
prefLabel
Importance of interferons in recovery from mousepox
@ast
Importance of interferons in recovery from mousepox
@en
P2093
P2860
P1433
P1476
Importance of interferons in recovery from mousepox
@en
P2093
Fredrickson TN
Karupiah G
Khairallah LH
P2860
P304
P407
P577
1993-07-01T00:00:00Z