Biomolecular interaction analysis in drug discovery using surface plasmon resonance technology.
about
Fragment screening and HIV therapeuticsTrends in protein-based biosensor assemblies for drug screening and pharmaceutical kinetic studiesUpdate of KDBI: Kinetic Data of Bio-molecular Interaction database.Mechanistic and kinetic characterization of hepatitis C virus NS3 protein interactions with NS4A and protease inhibitors.Integrating surface plasmon resonance biosensor-based interaction kinetic analyses into the lead discovery and optimization process.Targeting protein-protein interactions for therapeutic intervention: a challenge for the future.Emerging role of surface plasmon resonance in fragment-based drug discovery.Cellular membrane phospholipids act as a depository for quaternary amine containing drugs thus competing with the acetylcholine/nicotinic receptor.A fluorescence-based high throughput assay for the determination of small molecule-human serum albumin protein binding.Repositioning the substrate activity screening (SAS) approach as a fragment-based method for identification of weak binders.Targeting protein-protein interactions in hematologic malignancies: still a challenge or a great opportunity for future therapies?Native serotonin membrane receptors recognize 5-hydroxytryptophan-functionalized substrates: enabling small-molecule recognition.Surface plasmon resonance as a high throughput method to evaluate specific and non-specific binding of nanotherapeutics.SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligandsSystems biology and cancer stem cells.Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding.Binding of small molecules at interface of protein-protein complex - A newer approach to rational drug design.Protein-protein interactions: switch from classical methods to proteomics and bioinformatics-based approaches.Inhibition of P-fimbriated Escherichia coli adhesion by multivalent galabiose derivatives studied by a live-bacteria application of surface plasmon resonance.Synthesis of a new class of ribose functionalized dinucleotide cap analogues for biophysical studies on interaction of cap-binding proteins with the 5' end of mRNA.Biophysics: for HTS hit validation, chemical lead optimization, and beyond.Tracking of STAT3 signaling for anticancer drug-discovery based on localized surface plasmon resonance.Use of surface plasmon resonance in the binding study of vitamin D, metabolites and analogues with vitamin D binding protein.Exploitation of SPR to Investigate the Importance of Glycan Chains in the Interaction between Lactoferrin and Bacteria.Label-enhanced surface plasmon resonance: a new concept for improved performance in optical biosensor analysis.Modern surface plasmon resonance for bioanalytics and biophysics.Rapid ultrasensitive measurement of salivary cortisol using nano-linker chemistry coupled with surface plasmon resonance detection.Elucidation of direct competition and allosteric modulation of small-molecular-weight protein ligands using surface plasmon resonance methods.Confirming therapeutic target of protopine using immobilized β2 -adrenoceptor coupled with site-directed molecular docking and the target-drug interaction by frontal analysis and injection amount-dependent method.Quantitative monitoring of two simultaneously binding species using Label-Enhanced surface plasmon resonance.
P2860
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P2860
Biomolecular interaction analysis in drug discovery using surface plasmon resonance technology.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Biomolecular interaction analy ...... plasmon resonance technology.
@ast
Biomolecular interaction analy ...... plasmon resonance technology.
@en
type
label
Biomolecular interaction analy ...... plasmon resonance technology.
@ast
Biomolecular interaction analy ...... plasmon resonance technology.
@en
prefLabel
Biomolecular interaction analy ...... plasmon resonance technology.
@ast
Biomolecular interaction analy ...... plasmon resonance technology.
@en
P1476
Biomolecular interaction analy ...... plasmon resonance technology.
@en
P2093
Francis Mueller
Walter Huber
P304
P356
10.2174/138161206778743600
P577
2006-01-01T00:00:00Z