Blood clots are rapidly assembled hemodynamic sensors: flow arrest triggers intraluminal thrombus contraction
about
Microfluidics and coagulation biologyIn microfluidico: Recreating in vivo hemodynamics using miniaturized devicesA human platelet calcium calculator trained by pairwise agonist scanningMultiscale simulation of thrombus growth and vessel occlusion triggered by collagen/tissue factor using a data-driven model of combinatorial platelet signalling.Development and validation of a high throughput whole blood thrombolysis plate assay.Activated Monocytes Enhance Platelet-Driven Contraction of Blood Clots via Tissue Factor ExpressionA systems approach to hemostasis: 1. The interdependence of thrombus architecture and agonist movements in the gaps between platelets.A systems approach to hemostasis: 2. Computational analysis of molecular transport in the thrombus microenvironment.Shaping the platelet response to vascular injury.Microfluidic assessment of functional culture-derived platelets in human thrombi under flow.Kinetics and mechanics of clot contraction are governed by the molecular and cellular composition of the bloodA systems approach to hemostasis: 4. How hemostatic thrombi limit the loss of plasma-borne molecules from the microvasculature.Viscoelastic measurements of platelet function, not fibrinogen function, predicts sensitivity to tissue-type plasminogen activator in trauma patients.Systems Analysis of Thrombus Formation.Side view thrombosis microfluidic device with controllable wall shear rate and transthrombus pressure gradient.Detection of platelet sensitivity to inhibitors of COX-1, P2Y₁, and P2Y₁₂ using a whole blood microfluidic flow assay.Clot contraction: compression of erythrocytes into tightly packed polyhedra and redistribution of platelets and fibrin.Transport physics and biorheology in the setting of hemostasis and thrombosis.What Is the Biological and Clinical Relevance of Fibrin?Platelets as autonomous drones for hemostatic and immune surveillance.Computational Study of Thrombus Formation and Clotting Factor Effects under Venous Flow Conditions.Whole blood clot optical clearing for nondestructive 3D imaging and quantitative analysis.Minimum wound size for clotting: flowing blood coagulates on a single collagen fiber presenting tissue factor and von Willebrand factor.Fibrin, γ'-fibrinogen, and transclot pressure gradient control hemostatic clot growth during human blood flow over a collagen/tissue factor wound.Model predictions of deformation, embolization and permeability of partially obstructive blood clots under variable shear flow.A microengineered vascularized bleeding model that integrates the principal components of hemostasis.Contraction of Blood Clots Is Impaired in Acute Ischemic Stroke.Interplay of Platelet Contractility and Elasticity of Fibrin/Erythrocytes in Blood Clot Retraction.Hierarchical organization of the hemostatic response to penetrating injuries in the mouse macrovasculature.Erythrocyte compression index is impaired in patients with residual vein obstruction.Thrombosis in Cerebral Aneurysms and the Computational Modeling Thereof: A Review.
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P2860
Blood clots are rapidly assembled hemodynamic sensors: flow arrest triggers intraluminal thrombus contraction
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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2012年论文
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name
Blood clots are rapidly assemb ...... raluminal thrombus contraction
@ast
Blood clots are rapidly assemb ...... raluminal thrombus contraction
@en
type
label
Blood clots are rapidly assemb ...... raluminal thrombus contraction
@ast
Blood clots are rapidly assemb ...... raluminal thrombus contraction
@en
prefLabel
Blood clots are rapidly assemb ...... raluminal thrombus contraction
@ast
Blood clots are rapidly assemb ...... raluminal thrombus contraction
@en
P2860
P1476
Blood clots are rapidly assemb ...... raluminal thrombus contraction
@en
P2093
Ryan W Muthard
Scott L Diamond
P2860
P304
P356
10.1161/ATVBAHA.112.300312
P407
P577
2012-10-18T00:00:00Z