Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac
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Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Nef-associated kinase and simian AIDS in rhesus macaquesImmunogenicity of viral vector, prime-boost SIV vaccine regimens in infant rhesus macaques: attenuated vesicular stomatitis virus (VSV) and modified vaccinia Ankara (MVA) recombinant SIV vaccines compared to live-attenuated SIV.Impact of viral factors on very early in vivo replication profiles in simian immunodeficiency virus SIVagm-infected African green monkeys.In vivo replication capacity rather than in vitro macrophage tropism predicts efficiency of vaginal transmission of simian immunodeficiency virus or simian/human immunodeficiency virus in rhesus macaques.Occult systemic infection and persistent simian immunodeficiency virus (SIV)-specific CD4(+)-T-cell proliferative responses in rhesus macaques that were transiently viremic after intravaginal inoculation of SIVPathogenic conversion of live attenuated simian immunodeficiency virus vaccines is associated with expression of truncated NefEnhanced antiretroviral therapy in rhesus macaques improves RT-SHIV viral decay kineticsThe intracytoplasmic domain of the Env transmembrane protein is a locus for attenuation of simian immunodeficiency virus SIVmac in rhesus macaques.Simian-human immunodeficiency virus containing a human immunodeficiency virus type 1 subtype-E envelope gene: persistent infection, CD4(+) T-cell depletion, and mucosal membrane transmission in macaquesIn vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail.Characteristics of a pathogenic molecular clone of an end-stage serum-derived variant of simian immunodeficiency virus (SIV(F359)).Route of simian immunodeficiency virus inoculation determines the complexity but not the identity of viral variant populations that infect rhesus macaques.Suboptimal nucleotides in the infectious, pathogenic simian immunodeficiency virus clone SIVmac239.Protection against simian immunodeficiency virus vaginal challenge by using Sabin poliovirus vectorsPersistent infection of rhesus macaques with T-cell-line-tropic and macrophage-tropic clones of simian/human immunodeficiency viruses (SHIV).Development and characterization of an in vivo pathogenic molecular clone of equine infectious anemia virus.Rev-independent simian immunodeficiency virus strains are nonpathogenic in neonatal macaques.Virulence and reduced fitness of simian immunodeficiency virus with the M184V mutation in reverse transcriptase.Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the Env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251.Role of CD8+ cells in controlling replication of nonpathogenic Simian Immunodeficiency Virus SIVmac1A11.Persistence of extraordinarily low levels of genetically homogeneous human immunodeficiency virus type 1 in exposed seronegative individuals.Evidence for persistent, occult infection in neonatal macaques following perinatal transmission of simian-human immunodeficiency virus SF162P3Early events in tissues during infection with pathogenic (SIVmac239) and nonpathogenic (SIVmac1A11) molecular clones of simian immunodeficiency virus.Viral factors determine progression to AIDS in simian immunodeficiency virus-infected newborn rhesus macaques.vpr deletion mutant of simian immunodeficiency virus induces AIDS in rhesus monkeys.Vaginal transmission of chimeric simian/human immunodeficiency viruses in rhesus macaques.Genomic quasispecies associated with the initiation of infection and disease in ponies experimentally infected with equine infectious anemia virus.Simian immunodeficiency virus DNA vaccine trial in macaques.Early cytokine and chemokine gene expression in lymph nodes of macaques infected with simian immunodeficiency virus is predictive of disease outcome and vaccine efficacy.Rhesus macaques previously infected with simian/human immunodeficiency virus are protected from vaginal challenge with pathogenic SIVmac239.Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entryThe nef gene products of both simian and human immunodeficiency viruses enhance virus infectivity and are functionally interchangeable.The cytopathicity of a simian immunodeficiency virus Mne variant is determined by mutations in Gag and Env.Characterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope.Does viral tropism play a role in heterosexual transmission of HIV? Findings in the SIV-rhesus macaque modelT cell-tropic simian immunodeficiency virus (SIV) and simian-human immunodeficiency viruses are readily transmitted by vaginal inoculation of rhesus macaques, and Langerhans' cells of the female genital tract are infected with SIV.Titration of an SIVmac251 stock by vaginal inoculation of Indian and Chinese origin rhesus macaques: transmission efficiency, viral loads, and antibody responses.Targeted lymph-node immunization with whole inactivated simian immunodeficiency virus (SIV) or envelope and core subunit antigen vaccines does not reliably protect rhesus macaques from vaginal challenge with SIVmac251.Intravaginal inoculation of rhesus macaques with cell-free simian immunodeficiency virus results in persistent or transient viremia.A partially attenuated simian immunodeficiency virus induces host immunity that correlates with resistance to pathogenic virus challenge.
P2860
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P2860
Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Viral determinants of simian i ...... nic molecular clones of SIVmac
@ast
Viral determinants of simian i ...... nic molecular clones of SIVmac
@en
type
label
Viral determinants of simian i ...... nic molecular clones of SIVmac
@ast
Viral determinants of simian i ...... nic molecular clones of SIVmac
@en
prefLabel
Viral determinants of simian i ...... nic molecular clones of SIVmac
@ast
Viral determinants of simian i ...... nic molecular clones of SIVmac
@en
P2093
P2860
P1433
P1476
Viral determinants of simian i ...... nic molecular clones of SIVmac
@en
P2093
B Banapour
B L Lohman
C J Miller
K K Van Rompay
M L Marthas
N C Pedersen
P2860
P304
P407
P577
1993-10-01T00:00:00Z