Distinct roles for E2F proteins in cell growth control and apoptosis.
about
E2F7, a novel target, is up-regulated by p53 and mediates DNA damage-dependent transcriptional repressionPARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phasePhosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damageThe regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cellsDNA-damage response control of E2F7 and E2F8Highlight: BRCA1 and BRCA2 proteins in breast cancerHuman TFDP3, a novel DP protein, inhibits DNA binding and transactivation by E2FE2F1 induces p19INK4d, a protein involved in the DNA damage response, following UV irradiationThe novel ETS factor TEL2 cooperates with Myc in B lymphomagenesisInteraction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F functionInactivating a cellular intrinsic immune defense mediated by Daxx is the mechanism through which the human cytomegalovirus pp71 protein stimulates viral immediate-early gene expressionIdentification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteinsRb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signalsCDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phaseTwist is a potential oncogene that inhibits apoptosisAnalysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repressionE2f3 is critical for normal cellular proliferationThe E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complexTopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survivalTransforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding elementE2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpointsIdentification of E-box factor TFE3 as a functional partner for the E2F3 transcription factorE2f1, E2f2, and E2f3 control E2F target expression and cellular proliferation via a p53-dependent negative feedback loopDeregulated E2F transcriptional activity in autonomously growing melanoma cellsRegulation of E2F1 by BRCT domain-containing protein TopBP1Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cellsThe functional genomic response of developing embryonic submandibular glands to NF-kappa B inhibitionA neuronal-specific differentiation protein that directly modulates retinoid receptor transcriptional activationCell Proliferation in NeuroblastomaTargeting CDK6 in cancer: State of the art and new insightsRedox regulation of FoxO transcription factorsTo live or let die - complexity within the E2F1 pathwayCell growth-regulated expression of mammalian MCM5 and MCM6 genes mediated by the transcription factor E2FCa2+ and BMP-6 signaling regulate E2F during epidermal keratinocyte differentiationRegulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1EVI1 promotes cell proliferation by interacting with BRG1 and blocking the repression of BRG1 on E2F1 activityExpression of MCM10 and TopBP1 is regulated by cell proliferation and UV irradiation via the E2F transcription factorAberrant regulation of survivin by the RB/E2F family of proteinsDifferential activities of E2F family members: unique functions in regulating transcription
P2860
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P2860
Distinct roles for E2F proteins in cell growth control and apoptosis.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Distinct roles for E2F proteins in cell growth control and apoptosis.
@ast
Distinct roles for E2F proteins in cell growth control and apoptosis.
@en
type
label
Distinct roles for E2F proteins in cell growth control and apoptosis.
@ast
Distinct roles for E2F proteins in cell growth control and apoptosis.
@en
prefLabel
Distinct roles for E2F proteins in cell growth control and apoptosis.
@ast
Distinct roles for E2F proteins in cell growth control and apoptosis.
@en
P2093
P2860
P356
P1476
Distinct roles for E2F proteins in cell growth control and apoptosis.
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.14.7245
P407
P577
1997-07-01T00:00:00Z