Structure, function and amyloidogenic propensity of apolipoprotein A-I.
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The extreme N-terminal region of human apolipoprotein A-I has a strong propensity to form amyloid fibrilsAmyloidogenic mutations in human apolipoprotein A-I are not necessarily destabilizing - a common mechanism of apolipoprotein A-I misfolding in familial amyloidosis and atherosclerosisHuman apolipoprotein A-I-derived amyloid: its association with atherosclerosisHuman apolipoprotein A-I natural variants: molecular mechanisms underlying amyloidogenic propensityAmyloidogenic propensity of a natural variant of human apolipoprotein A-I: stability and interaction with ligandsStructural and Functional Analysis of the ApolipoproteinA-I A164S VariantThe crystal structure of the C-terminal truncated apolipoprotein A-I sheds new light on amyloid formation by the N-terminal fragment.Proteomics in protein misfolding diseases.Amyloid triangles, squares, and loops of apolipoprotein C-III.Methionine oxidation induces amyloid fibril formation by full-length apolipoprotein A-I.NBD-labeled phospholipid accelerates apolipoprotein C-II amyloid fibril formation but is not incorporated into mature fibrils.Novel N-terminal mutation of human apolipoprotein A-I reduces self-association and impairs LCAT activationMass spectrometry analysis reveals non-mutated apolipoprotein A1 lumbosacral radiculoplexus amyloidoma.Conformational and aggregation properties of the 1-93 fragment of apolipoprotein A-I.Effect of the amyloidogenic L75P apolipoprotein A-I variant on HDL subpopulations.Amyloid nephropathyMyeloperoxidase-mediated Methionine Oxidation Promotes an Amyloidogenic Outcome for Apolipoprotein A-I.Amyloidogenic Mutation Promotes Fibril Formation of the N-terminal Apolipoprotein A-I on Lipid Membranes.Cellular interaction and cytotoxicity of the iowa mutation of apolipoprotein A-I (ApoA-IIowa) amyloid mediated by sulfate moieties of heparan sulfate.Effects of disulfide bond formation and protein helicity on the aggregation of activating transcription factor 5Structural Stability and Local Dynamics in Disease-Causing Mutants of Human Apolipoprotein A-I: What Makes the Protein Amyloidogenic?Dual role of an N-terminal amyloidogenic mutation in apolipoprotein A-I: destabilization of helix bundle and enhancement of fibril formation.Hereditary apolipoprotein AI-associated amyloidosis in surgical pathology specimens: identification of three novel mutations in the APOA1 geneAmyloidogenic variant of apolipoprotein A-I elicits cellular stress by attenuating the protective activity of angiogenin.Hot spots in apolipoprotein A-II misfolding and amyloidosis in mice and men.Apolipoproteins and amyloid fibril formation in atherosclerosis.Redox proteomics gives insights into the role of oxidative stress in alkaptonuria.HDL and cholesterol handling in the brain.Amyloid-Forming Properties of Human Apolipoproteins: Sequence Analyses and Structural InsightsCross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis.Apolipoprotein A-I: the dual face of a protein.Vascular alterations in apolipoprotein A-I amyloidosis (Leu75Pro). A case-control study.The fibrillogenic L178H variant of apolipoprotein A-I forms helical fibrils.Membrane effects of N-terminal fragment of apolipoprotein A-I: a fluorescent probe study.Iowa Mutant Apolipoprotein A-I (ApoA-IIowa) Fibrils Target Lysosomes.Insights into the fate of the N-terminal amyloidogenic polypeptide of ApoA-I in cultured target cellsAmyPro: a database of proteins with validated amyloidogenic regions.Renal ApoA-1 amyloidosis with Glu34Lys mutation and intra-amyloid lipid accumulation.Clinical characteristics of laryngeal versus nonlaryngeal amyloidosis.The polyphenol (-)-epigallocatechin-3-gallate prevents apoA-IIowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity.
P2860
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P2860
Structure, function and amyloidogenic propensity of apolipoprotein A-I.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Structure, function and amyloidogenic propensity of apolipoprotein A-I.
@ast
Structure, function and amyloidogenic propensity of apolipoprotein A-I.
@en
type
label
Structure, function and amyloidogenic propensity of apolipoprotein A-I.
@ast
Structure, function and amyloidogenic propensity of apolipoprotein A-I.
@en
prefLabel
Structure, function and amyloidogenic propensity of apolipoprotein A-I.
@ast
Structure, function and amyloidogenic propensity of apolipoprotein A-I.
@en
P2093
P2860
P1433
P1476
Structure, function and amyloidogenic propensity of apolipoprotein A-I.
@en
P2093
Giampaolo Merlini
Guido Franceschini
Laura Obici
Monica Stoppini
Sofia Giorgetti
Vittorio Bellotti
P2860
P304
P356
10.1080/13506120600960288
P577
2006-12-01T00:00:00Z