hSSB1 regulates both the stability and the transcriptional activity of p53 - Wikidata - awgldk - TriplyDB

hSSB1 regulates both the stability and the transcriptional activity of p53

hSSB1 regulates both the stability and the transcriptional activity of p53

http://www.wikidata.org/entity/Q36655029

about

Human single-stranded DNA binding proteins are essential for maintaining genomic stability CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair.Targeting the anaphase-promoting complex/cyclosome (APC/C)- bromodomain containing 7 (BRD7) pathway for human osteosarcoma.FBXL5-mediated degradation of single-stranded DNA-binding protein hSSB1 controls DNA damage response.Paradoxical role of CBX8 in proliferation and metastasis of colorectal cancer.Human single-stranded DNA binding proteins: guardians of genome stability.Acetylation-dependent function of human single-stranded DNA binding protein 1.hSSB1 associates with and promotes stability of the BLM helicase TEL2 suppresses metastasis by down-regulating SERPINE1 in nasopharyngeal carcinoma.A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution.UPregulated single-stranded DNA-binding protein 1 induces cell chemoresistance to cisplatin in lung cancer cell lines.Peptides derived from the dependence receptor ALK are proapoptotic for ALK-positive tumors.Oncogenic roles of carbonic anhydrase IX in human nasopharyngeal carcinoma.Chromobox homolog 4 is correlated with prognosis and tumor cell growth in hepatocellular carcinoma.Mouse models uncap novel roles of SSBs.CDP138 silencing inhibits TGF-β/Smad signaling to impair radioresistance and metastasis via GDF15 in lung cancer hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway.Identification of two novel BRCA1-partner genes in the DNA double-strand break repair pathway.CREBBP and p300 lysine acetyl transferases in the DNA damage response.CDK16 Phosphorylates and Degrades p53 to Promote Radioresistance and Predicts Prognosis in Lung Cancer.A functional polymorphism of SSBP1 gene predicts prognosis and response to chemotherapy in resected gastric cancer patients.An integrated approach identifies new oncotargets in melanoma.S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer.

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P2860

hSSB1 regulates both the stability and the transcriptional activity of p53

http://www.wikidata.org/entity/Q36655029

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

@zh-hk

2012年論文

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2012年論文

@zh-tw

2012年论文

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2012年论文

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2012年论文

@zh-cn

name

hSSB1 regulates both the stability and the transcriptional activity of p53

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hSSB1 regulates both the stability and the transcriptional activity of p53

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type

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hSSB1 regulates both the stability and the transcriptional activity of p53

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hSSB1 regulates both the stability and the transcriptional activity of p53

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hSSB1 regulates both the stability and the transcriptional activity of p53

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hSSB1 regulates both the stability and the transcriptional activity of p53

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hSSB1 regulates both the stability and the transcriptional activity of p53

@en

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Fenju Lai

http://www.w3.org/2001/XMLSchema#string

Jianjun Tang

http://www.w3.org/2001/XMLSchema#string

Jingying Cao

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Kaishun Hu

http://www.w3.org/2001/XMLSchema#string

Li Wang

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Qiong Chen

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Ruhua Zhang

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Sheng-Ping Li

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Shuangbing Xu

http://www.w3.org/2001/XMLSchema#string

Tiebang Kang

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P2860

Nucleophosmin regulates the stability and transcriptional activity of p53

BRD7 is a candidate tumour suppressor gene required for p53 function

Binding and modulation of p53 by p300/CBP coactivators

HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response

Mdm2 promotes the rapid degradation of p53

SOSS complexes participate in the maintenance of genomic stability

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

hSSB1 binds and protects p21 from ubiquitin-mediated degradation and positively correlates with p21 in human hepatocellular carcinomas

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

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423-435

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scholarly article

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10.1038/CR.2012.162

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3

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23

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