Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal - Wikidata - awgldk - TriplyDB

Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

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U2 small nuclear ribonucleoprotein particle (snRNP) auxiliary factor of 65 kDa, U2AF65, can promote U1 snRNP recruitment to 5' splice sites SRp30c is a repressor of 3' splice site utilization.The conserved RNA recognition motif 3 of U2 snRNA auxiliary factor (U2AF 65) is essential in vivo but dispensable for activity in vitro RNA binding protein sex-lethal (Sxl) and control of Drosophila sex determination and dosage compensation Absence of interdomain contacts in the crystal structure of the RNA recognition motifs of Sex-lethal HYAL1LUCA-1, a candidate tumor suppressor gene on chromosome 3p21.3, is inactivated in head and neck squamous cell carcinomas by aberrant splicing of pre-mRNA Biochemical and functional analysis of Drosophila-sciara chimeric sex-lethal proteins Polypyrimidine tract binding protein antagonizes exon definition An N-terminal truncation uncouples the sex-transforming and dosage compensation functions of sex-lethal.Switch in 3' splice site recognition between exon definition and splicing catalysis is important for sex-lethal autoregulation.The translation initiation factor eIF4E regulates the sex-specific expression of the master switch gene Sxl in Drosophila melanogaster.The Drosophila splicing regulator sex-lethal directly inhibits translation of male-specific-lethal 2 mRNA Differential recognition of the polypyrimidine-tract by the general splicing factor U2AF65 and the splicing repressor sex-lethal Modulation of msl-2 5' splice site recognition by Sex-lethal Sex lethal and U2 small nuclear ribonucleoprotein auxiliary factor (U2AF65) recognize polypyrimidine tracts using multiple modes of binding.RNA-protein interactions that regulate pre-mRNA splicing.The gene Sex-lethal of the Sciaridae family (order Diptera, suborder Nematocera) and its phylogeny in dipteran insects.Evidence for 3' untranslated region-dependent autoregulation of the Drosophila gene encoding the neuronal nuclear RNA-binding protein ELAV Polypyrimidine track-binding protein binding downstream of caspase-2 alternative exon 9 represses its inclusion.A conditional role of U2AF in splicing of introns with unconventional polypyrimidine tracts

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Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

http://www.wikidata.org/entity/Q36655529

description

1997 nî lūn-bûn

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1997年の論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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1997年论文

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1997年论文

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name

Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

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Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

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type

label

Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

@ast

Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

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prefLabel

Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

@ast

Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

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PNAS.94.14.7343

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Proceedings of the National Academy of Sciences of the United States of America

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Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

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Granadino B

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Green MR

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Penalva LO

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Sánchez L

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Valcárcel J

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P2860

Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit

Cloning and domain structure of the mammalian splicing factor U2AF

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer

Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins

Alternatively spliced transcripts of the sex-determining gene tra-2 of Drosophila encode functional proteins of different size

Functional changes associated with structural alterations induced by mobilization of a P element inserted in the Sex-lethal gene of Drosophila.

Regulation of the gene Sex-lethal: a comparative analysis of Drosophila melanogaster and Drosophila subobscura.

Two closely linked mutations in Drosophila melanogaster that are lethal to opposite sexes and interact with daughterless

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10.1073/PNAS.94.14.7343

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9207093

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