The human cut homeodomain protein represses transcription from the c-myc promoter.
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Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genesThe mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phaseS phase-specific proteolytic cleavage is required to activate stable DNA binding by the CDP/Cut homeodomain proteinHomeoproteins CDP and SATB1 interact: potential for tissue-specific regulationCCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcriptionRegulation of the homeodomain CCAAT displacement/cut protein function by histone acetyltransferases p300/CREB-binding protein (CBP)-associated factor and CBPPhosphorylation of the CCAAT displacement protein (CDP)/Cux transcription factor by cyclin A-Cdk1 modulates its DNA binding activity in G(2)Genetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertilityCux/CDP homeoprotein is a component of NF-muNR and represses the immunoglobulin heavy chain intronic enhancer by antagonizing the bright transcription activatorDorsal-mediated repression requires the formation of a multiprotein repression complex at the ventral silencer.CDP is a repressor of mouse mammary tumor virus expression in the mammary gland.The homeodomain protein CDP regulates mammary-specific gene transcription and tumorigenesis.CDP binding to multiple sites in the mouse mammary tumor virus long terminal repeat suppresses basal and glucocorticoid-induced transcriptionDifferentiation-induced cleavage of Cutl1/CDP generates a novel dominant-negative isoform that regulates mammary gene expression.Transcriptional regulation of the human KiSS1 geneHepatomegaly in transgenic mice expressing the homeobox gene Cux-1Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in downregulation of p27(kip1) expression during nephrogenesis, glomerular abnormalities, and multiorgan hyperplasia.Transcription of the human EAP1 gene is regulated by upstream components of a puberty-controlling Tumor Suppressor Gene network.CCAAT displacement protein, a regulator of differentiation-specific gene expression, binds a negative regulatory element within the 5' end of the human papillomavirus type 6 long control region.C/EBP epsilon mediates myeloid differentiation and is regulated by the CCAAT displacement protein (CDP/cut).A Myc-associated zinc finger protein binding site is one of four important functional regions in the CD4 promoter.Interaction of the CCAAT displacement protein with shared regulatory elements required for transcription of paired histone genes.The human cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy.The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-myc P2 minimal promoter.DNA-binding specificity of the cut repeats from the human cut-like proteinThe matrix attachment region-binding protein SATB1 participates in negative regulation of tissue-specific gene expression.Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease.CCAAT displacement protein regulates nuclear factor-kappa beta-mediated chemokine transcription in melanoma cellsThe homeodomain protein Cux1 interacts with Grg4 to repress p27 kip1 expression during kidney development.Antisense oligonucleotides to Cux-1, a Cut-related homeobox gene, cause increased apoptosis in mouse embryonic kidney culturesThe chromatin structure of the dual c-myc promoter P1/P2 is regulated by separate elements.YY1 binds five cis-elements and trans-activates the myeloid cell-restricted gp91(phox) promoter.CCAAT displacement protein (CDP/cut) binds a negative regulatory element in the human tryptophan hydroxylase gene.CCAAT displacement protein binds to and negatively regulates human papillomavirus type 6 E6, E7, and E1 promoters.The Promyelocytic Leukemia Zinc Finger (PLZF ) gene is a novel transcriptional target of the CCAAT-Displacement-protein (CUX1) repressor.A novel colonic repressor element regulates intestinal gene expression by interacting with Cux/CDPCDP/Cux stimulates transcription from the DNA polymerase alpha gene promoter.Analysis of the interaction of the adenovirus L1 52/55-kilodalton and IVa2 proteins with the packaging sequence in vivo and in vitro.Coexpression of Cux-1 and Notch signaling pathway components during kidney development.Immortalization of human WI38 cells is associated with differential activation of the c-myc origins.
P2860
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P2860
The human cut homeodomain protein represses transcription from the c-myc promoter.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
The human cut homeodomain protein represses transcription from the c-myc promoter.
@ast
The human cut homeodomain protein represses transcription from the c-myc promoter.
@en
type
label
The human cut homeodomain protein represses transcription from the c-myc promoter.
@ast
The human cut homeodomain protein represses transcription from the c-myc promoter.
@en
prefLabel
The human cut homeodomain protein represses transcription from the c-myc promoter.
@ast
The human cut homeodomain protein represses transcription from the c-myc promoter.
@en
P2860
P356
P1476
The human cut homeodomain protein represses transcription from the c-myc promoter.
@en
P2093
P2860
P304
P356
10.1128/MCB.14.6.4251
P407
P577
1994-06-01T00:00:00Z